3CAI


Conserved Protein Domain Family
am_tr_V_VC1184

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TIGR01976: am_tr_V_VC1184 
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cysteine desulfurase family protein, VC1184 subfamily
This model describes a subfamily of probable pyridoxal phosphate-dependent enzymes in the aminotransferase class V family (pfam00266). The most closely related characterized proteins are active as cysteine desulfurases, selenocysteine lyases, or both; some are involved in FeS cofactor biosynthesis and are designated NifS. An active site Cys residue present in those sequences, in motifs resembling GHHC or GSAC, is not found in this family. The function of members of this family is unknown, but seems unlike to be as an aminotransferase. [Unknown function, Enzymes of unknown specificity]
Statistics
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PSSM-Id: 273906
Aligned: 7 rows
Threshold Bit Score: 534.717
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3CAI_A        11 YDVARVRGLHPSLGD-G-----WVHFDAPAGMLIPDSVATTVSTAFRRSGASTVGAHPSA-RRSAAVLDAAREAVADLVN 83  Mycobacterium t...
WP_001212916   3 FTPESVRQQFPALAQ-IvndkpVVFFDGPGGSQVPQSVLDAMVAYLGRYNANLGGHYFSS-KKTVELVQSAREHVQALLN 80  Vibrio cholerae
WP_010913214  14 FPVDTIRTMFPALQRaGd----FIFMDNAAGAQIPQSVLDAVTNHLVSHNVQRGGRYGRS-VTVDQSVADARTSVALLIN 88  Mesorhizobium loti
WP_003977776   3 LDVAAIRAHVPALKS-Gt-----ARFDAPGGTQTPQPVIDAIAAALTAPLANRGRNTEGE-RNADRIVDEARSALADLLG 75  Streptomyces
WP_023641536   3 YDVARVRGLHPSLGD-G-----WVHFDAPAGMLIPDSVATTVSTAFRRSGASTVGAHPSA-RRSAAVLDAAREAVADLVN 75  Mycobacterium t...
WP_010886797   7 ITREALRTQFPSLA--Gg----RAYLDNAAGGLLPTRSIQAVTEHLTRFGATNAMPGHAPgQQIGQLKARAREGTALFLN 80  Deinococcus rad...
WP_010909127   7 FPIEAVRGQFPALSL-TdkgrrRIYLDNPAGTQVPQAVADAVSRCLLTTNANLGGYFETT-IAAQSVVDDAHRAMADFLG 84  Mesorhizobium loti
3CAI_A        84 ADPG-G-VVLGADRAVLLSLLAEASSSRAGLGYEVIVSRLDDEANIAPWLRAAHRYGAKVKWAEVDIETGELPTWQWESL 161 Mycobacterium t...
WP_001212916  81 ASTP-EsIVFGANMTSLTFQFSRAISRDWRVGDEVIVTALDHYSNVSSWQQAAQDKGAIVHQARVNTADCTLDQAHLLSL 159 Vibrio cholerae
WP_010913214  89 AYSPaE-ICFGMNATSFIRLVSLGIGQMLSERDEIVITDMDHDANIATWLALET-AGAKFKWWRMRE-DGNLHVDDLRPL 165 Mesorhizobium loti
WP_003977776  76 TTPG-T-VVFGRSATQLAYDLSRTLAKGWGPGDEVVVTRLDHDSNIRPWVQAAEAAGADVRWADFDPATGELRPEHLAAV 153 Streptomyces
WP_023641536  76 ADPG-G-VVLGADRAVLLSLLAEASSSRAGLGYEVIVSRLDDEANIAPWLRAAHRYGAKVKWAEVDIETGELPTWQWESL 153 Mycobacterium t...
WP_010886797  81 AEAP-D-VALGPSATALAFRLAAAFARLWGPGDEVIVSGLEHEANASPW-RELERVGVTVKVWHARAPEMRLHPDDLAAL 157 Deinococcus rad...
WP_010909127  85 AASP-EeIIIGANMTTLTYHMSRTLGRTLKPGDEIILTRMDHEGNVSPWLQLAEDLSLVVRWLPFDEKSWQVEEAALTGL 163 Mesorhizobium loti
3CAI_A       162 ISKSTRLVAVNSASGTLGGVTDLRAMTKLVHDVGALVVVDHSAAAPYRLLDIRETDADVVTVNAHAWGGPPIGAMVFRDP 241 Mycobacterium t...
WP_001212916 160 INPRTRLVAVTFASNTTGSLVELEAIIEAAHQVGAMVYVDAVHYLPHHLPDVQALGCDFLACSAYKFFGPHVGIVYVAPQ 239 Vibrio cholerae
WP_010913214 166 VSDRTRLVACTVTAHSIGSIVDVASVAEIAHAAGAEVFLDCVHYGPHGLIDVQAWDCDYLVCSGYKNFSPHMGFLWGRFD 245 Mesorhizobium loti
WP_003977776 154 LGPRTRLVAVTAASNLIGTMPDLPALASLVHANGAHFHVDAVHYASHAVVDLAATGADTLVCSPYKFLGPHLGVLTGRAE 233 Streptomyces
WP_023641536 154 ISKSTRLVAVNSASGTLGGVTDLRAMTKLVHDVGALVVVDHSAAAPYRLLDIRETDADVVTVNAHAWGGPPIGAMVFRDP 233 Mycobacterium t...
WP_010886797 158 LSPRTRLVAVTAASNVLGVAPDIAAITAQVRAAGGWTVVDAVHAAPHLLPDVQAWGADFVTFSPYKVFGPHLGGLWIRPE 237 Deinococcus rad...
WP_010909127 164 LSDKTRLVALNYASNLTGSINRVKALTAIAKRAGALVYVDAVQFAPHGLIDVQDLGCDLLICSAYKFFGPHMGILWGRRE 243 Mesorhizobium loti
3CAI_A       242 SVMNSFGSVSTNPYATGPARLEIGVHQFGLLAGVVASIEYLAALDe----SARGSRRERLAVSMQSADAYLNRVFDYLMV 317 Mycobacterium t...
WP_001212916 240 WQNTILPYKVEPATNQGPGRFETGTLSFEGLAGVIAVVQYLAQWG-----DPNSRLRERLVESYQQYQQHEQRLSEYFLQ 314 Vibrio cholerae
WP_010913214 246 TLKRLPTFREDFIPDEPPYKVEAGTFIYENVSGMDAAVQYLELIGrnlapSNNRSRRENIVAGMGAIRDYELLLAREMLA 325 Mesorhizobium loti
WP_003977776 234 LLESLRPDKLLPSADTVPERFELGTLPYELLAGTSAAVDFLAGLEa----EAEGSRRDRLVASFAALEAHEEALRERLER 309 Streptomyces
WP_023641536 234 SVMNSFGSVSTNPYATGPARLEIGVHQFGLLAGVVASIEYLAALDe----SARGSRRERLAVSMQSADAYLNRVFDYLMV 309 Mycobacterium t...
WP_010886797 238 LRPQLPWPRLSFVEDGDITGIEHGTPQYELLAGWLGTLDYLRELGg----GDT-LTRAALVAAFEQIAALERPVTEALLT 312 Deinococcus rad...
WP_010909127 244 IIDGLKPYKCRCSSNGLPERFELGTPQIELMAGLMAAVDYFAGLGva--aGEGGSRRQKIARAFEVSIAYENPLAQRLID 321 Mesorhizobium loti
3CAI_A       318 SLRSLPLVMLIG-----RPEAQIPVVSFAVHKVPADRVVQRLADNGILAIAN--TGSRVLDVLGVNDVGGAVTVGLAHYS 390 Mycobacterium t...
WP_001212916 315 KLSDMPALKLHGlq-laDAAKRTPTFALTCTDCTPQSMAKMLGEQNVCVWNGhfYALGLVRQLGLESSGGVLRIGLMHYN 393 Vibrio cholerae
WP_010913214 326 VLKGCG-ATIYGvadeaRLNERVPTFCFNIGRLSPQRIVEEMADMQIGIRDGhmYAPRLMKRLNLSMDSGAIRASLVHYN 404 Mesorhizobium loti
WP_003977776 310 GLAELGGITVYSr-----AARRTPTLLFTVAGLRPADVYRQLAERAVDAPAGsfYAVEAARRLGLGDEGG-VRVGLAPYS 383 Streptomyces
WP_023641536 310 SLRSLPLVMLIGr-----PEAQIPVVSFAVHKVPADRVVQRLADNGILAIAN--TGSRVLDVLGVNDVGGAVTVGLAHYS 382 Mycobacterium t...
WP_010886797 313 GLLARPYVTVYGp---qTLEGRVGTVAFQVQGEAPLDTALRLSAQGVDVAAGhfYAVQPLRDLGLY-PDGVARASLAHYT 388 Deinococcus rad...
WP_010909127 322 GLSDIPGLTIHGitdrkRLADRVPTVSFTVDGIVPETIVRQMNAENIFLWSGhnYAWEIVHQLGIPAEQGVVRIGIAHYN 401 Mesorhizobium loti
3CAI_A       391 TMAEVDQLVRAL 402 Mycobacterium tuberculosis H37Rv
WP_001212916 394 TTEEIDHLFALL 405 Vibrio cholerae
WP_010913214 405 TVEEVHKFGEAL 416 Mesorhizobium loti
WP_003977776 384 SAEDVDRLLTAL 395 Streptomyces
WP_023641536 383 TMAEVDQLVRAL 394 Mycobacterium tuberculosis
WP_010886797 389 SEEDVARLLAAL 400 Deinococcus radiodurans
WP_010909127 402 TAAEIDETLESV 413 Mesorhizobium loti
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