Conserved Protein Domain Family
zf-CCHC_3

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pfam13917: zf-CCHC_3 
Zinc knuckle
The zinc knuckle is a zinc binding motif composed of the the following CX2CX4HX4C where X can be any amino acid. The motifs are mostly from retroviral gag proteins (nucleocapsid). Prototype structure is from HIV. Also contains members involved in eukaryotic gene regulation, such as C. elegans GLH-1. Structure is an 18-residue zinc finger.
Statistics
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PSSM-Id: 404753
Aligned: 19 rows
Threshold Bit Score: 42.7764
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q7QJY9        11 ENVRAACKKCGFPGHLTYQCRnyltvdpqsqA--------Vvp---vqKRPGSESPEQNY 59  Anopheles gambiae str. PEST
XP_001696858  27 NRQQARCQRCLQIGHYTYECK----------Nea----ayA-------ARPSRTQQLKQG 65 
1_pfamImport   1 NKQHVRCQKCLEFGHWTYECT----------Gkr----kyL-------HRPSRTAELKKA 39 
XP_001844226 102 FPKGVRCQKCLEFGHWSYECK----------Gkr----kyV-------HRSSRTQLLKKN 140
A0E2U0        31 DAAAVRCQRCLKYGHLTYECK----------Nen----vyL-------YRPSRTMQFKEK 69  Paramecium tetraurelia
2_pfamImport   1 AIYNIACQRCGGKGHMAHECYn--------tGgn----kyEmleeerpARPEHTAVIQPK 48 
XP_002676901  17 EGGGGFCQKCFTEGHWTYQCK----------GekapsttyT-------KRLSHTEKLEMM 59 
XP_002997002  44 SSVAAMCQKCLRRGHWTYECK----------Nga----vyV-------QRPSRSQQLRNP 82 
XP_024395561  94 FGGSQQCQKCFQMGHWTYECK----------Ndr----vyI-------SRPTRTQQLANP 132
XP_002519204  90 AGGTAQCQKCFQTGHWTFECK----------Ner----vyM-------ARPSRTQQLKNP 128
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