4ACJ


Conserved Protein Domain Family
TLD

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pfam07534: TLD 
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TLD
This domain is predicted to be an enzyme and is often found associated with pfam01476. It's structure consists of a beta-sandwich surrounded by two helices and two one-turn helices.
Statistics
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PSSM-Id: 429519
Aligned: 98 rows
Threshold Bit Score: 65.3225
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4ACJ_A  31 LA-FSTSKHGMSIKTLYRAMQ------DQdSPMLLVIKdSDGQIFGALASEPFKVS-EGFYGTGETFLFTFYPEFEAYKW 102
Q0V5D5 399 RL-LPAKASSTRERALENLLPp-----KRyPSSIPETAtNQSLVYGGFVPSQWKNTgKACFGDANTKLFQLSPTHDVFSP 472 Parastagonospora nodo...
A5DMB8 368 ET-FDSE-----YPRFFRS--------SE-SPLKPWQQpNDKITYAVLVHEPWKVSnKKNFGDTNTTIIALEPRLDVFKG 432 Meyerozyma guilliermo...
A5DSQ8 413 R----TIDTNRRYQEFDETYPkffqanED-LLKSWQYTnDR-ITYCVLINQPWQNSnKKNFGDEKSLILSLEPRADYYTS 486 Lodderomyces elongisp...
Q6BHX4 415 VK-NKTMKHNNRYIQFNEMYPsyf-rsSE-SPKKDWQDdNDKMTYAVIINSPWKNSnKNNFGDEDTVILNLSPRFDFYKS 491 Debaryomyces hansenii...
Q756J6 343 EI-VCTK--NKRYKAFLQDYPal--kdAE-QQLALCDRkKRNLIYAIFVRDPWKITnKDLFGDMDTTIIQLAPRQKIFKA 416 Eremothecium gossypii...
Q6CMD3 356 DA-YAV--KNPRYRNFLQEYGklk-seDQ-HLDTLSKKkRK-LLFAVCIRDPWKVSnKDLFGDSSTKIIQLHPRQEIFDA 429 Kluyveromyces lactis ...
Q6FKH1 343 ES-YADS-KNPRYRSFLYSFPklr-enDQ-NLDAIHLTkKK-VTYAVYIDEPWKVSnKEKFGATNMTIMELTPQQKTYQS 417 [Candida] glabrata CB...
A7TNS4 346 IE-YSEN-KNPRYKRFLEEYPklk-deDQ-EMDDCHNLkKK-VTFAVYIDEPWRVTnKNYFGEKRTSIIELSPRQDKFNS 420 Vanderwaltozyma polys...
Q12108 350 NSeEYAAEKNPRYRHFLEEFPklk-esDQ-MMDASHLNkRK-TTFAVYIDDPWKVTnKDYFGDLNTRIIEISPRQDIYKV 426 Saccharomyces cerevis...
4ACJ_A 103 -----TGDNLFFIKGDMdS-----LAFGGGSg----------------EFGLWLDGDLYHXRNHSC--------KTFGNP 148
Q0V5D5 473 -----SQYADNYVYFNKsPthppgLGFGTKIplqssahshsqetfkpgVVSLHLDDALEFGIFTHIsg----ggGTFHSS 543 Parastagonospora nodo...
A5DMB8 433 -----IASESIYFNTLGmG-----LGFGNSQpinkntl----kryapgSVSLTIEANLEFAVFRHIssqagsgiTSFATG 498 Meyerozyma guilliermo...
A5DSQ8 487 lhseilkgqLIYFNNSGm-----gLGFGNAQplnksnn----kkyypgDVSLTIESNLEFAVFRHLgslstnatTYFNRS 557 Lodderomyces elongisp...
Q6BHX4 492 vhnpvLNGKSIYFNNLGmG-----LGFGNSQpinkntv----kkflpgDISLTIEANLEFAIFRHIsspn-sngASFFQK 561 Debaryomyces hansenii...
Q756J6 417 -----QEAPNIYFNAVGgG-----IGFGSSQpsvkpag----kryfpgNVSFTVDPSMEFAVFRNVgd-----gGMFSHG 477 Eremothecium gossypii...
Q6CMD3 430 dpf---ktgNVYFNTVGg-----gIGIGSSQpiikang----kkyfpgNVSLTIDSSLEFGIFRHlg-----agGSFKPG 492 Kluyveromyces lactis ...
Q6FKH1 418 cm-----erTMYFNTIGg-----gIGVGSEQpivkqnd----ikfipgNISLTMDSSLEFGVFRHvg-----agGGFKTS 478 [Candida] glabrata CB...
A7TNS4 421 lk-----vgSVYFNTIGg-----gIGIGNNQpvtklns----vryapgNVSLTLDNTLEFGVFRHtg-----ygGTIGPS 481 Vanderwaltozyma polys...
Q12108 427 -----NQKGTIYFNTIGgG-----IGIGDKQplikpas----kryipgNVSLTFDSTLEFAVFRNTgy-----gGSLDPG 487 Saccharomyces cerevis...
4ACJ_A 149 MLSm---------KEDFFVQDIEIWSFE 167
Q0V5D5 544 GLPcrkg---kdwQDRFEIEEIEVWGCG 568 Parastagonospora nodorum SN15
A5DMB8 499 VQPdisg---qdyEDRFLITDLEVWGVG 523 Meyerozyma guilliermondii ATCC 6260
A5DSQ8 558 RLPstva--hedfEDRFLITDLEVWGIG 583 Lodderomyces elongisporus NRRL YB-4239
Q6BHX4 562 SKQneis--vqdfEDRFMISDLEVWGIG 587 Debaryomyces hansenii CBS767
Q756J6 478 SAVpapaeqplsyEHRLMIKDLEVWGYG 505 Eremothecium gossypii ATCC 10895
Q6CMD3 493 RLIsgrgeernsfEYRFIIQDVEVWGCG 520 Kluyveromyces lactis NRRL Y-1140
Q6FKH1 479 LLDndds---ksfEIRFIIQNVEVWGCG 503 [Candida] glabrata CBS 138
A7TNS4 482 ELLkknneenkafEIRFLIRDVEVWGCG 509 Vanderwaltozyma polyspora DSM 70294
Q12108 488 LLSmerkeenspyELHFLIQDVEVWGCG 515 Saccharomyces cerevisiae S288C
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