Conserved Protein Domain Family
BTB_POZ_NPR_plant

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cd18310: BTB_POZ_NPR_plant 
BTB (Broad-Complex, Tramtrack and Bric a brac) /POZ (poxvirus and zinc finger) domain found in plant regulatory proteins, NPR1-4, and similar proteins
NPR1 and NPR2 are essential for pathogenicity and the utilization of many nitrogen sources. NPR1 is also called nitrogen pathogenicity regulation protein NPR1, non-inducible immunity protein 1 (Nim1), nonexpresser of PR genes 1, or salicylic acid insensitive 1 (Sai1). It acts as a transcription coactivator that plays dual roles in regulating plant immunity. NPR3 and NPR4 are involved in negative regulation of defense responses against pathogens in plant. NPR proteins contain a BTB domain, DUF3420, ankyrin (ANK) repeats, and a conserved C-terminal domain. The BTB/POZ domain is a common protein-protein interaction motif of about 100 amino acids.
Statistics
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PSSM-Id: 349619
Aligned: 12 rows
Threshold Bit Score: 159.394
Created: 11-Sep-2017
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q5ICL9        36 EELSSNLEQLLTNPd--cDYTDAEIIIEe------eANPVSVHRCVLAARSKFFLDLFkkdkdsse-------------- 93  thale cress
Q8L746        42 TKLSSNLEQLLSNSd--cDYSDAEIIVD--------GVPVGVHRCILAARSKFFQDLFkkekkisk-------------- 97  thale cress
XP_002992598  48 NKLGQDLEGLVTSAedchFYSDAEIIVAe-------GVTVPVHRCILAARSPFLRRIFaekqre---------------- 104 Selaginella moe...
XP_001778211   2 QKLGSDLETLIRIPd--qEYSDLTIILD--------GKQVPIHRCILAARCPGIRKVFsemgvtgg-------------- 57  Physcomitrella ...
XP_001757508  10 RTLSLDFLSLLGEGq---VFSDVAFEVE--------GRHVYAHRCVLAARSPFFRTIFwsdvqmms-------------- 64  Physcomitrella ...
XP_002986952   8 KQLSSDLLNLLANGq---AFSDVTFTVE--------GRPVYAHKCVLAARSQFFRMIFcsseas---------------- 60  Selaginella moe...
Q0JJ01        79 NRLSANLERLLLDSd--lDCSDADVDVAd------gGPPVPVHRCILAARSTFFYNLFaargrggdgaagggggg----- 145 Japanese rice
Q75HA6        32 GRLSRNLENLLDPAf--lNCADAEIVLAsgggdpggGAVVGVHRCILAARSRFFYDHFssapapapat------------ 97  Japanese rice
A2CIR7         6 KSLSMDYLNLLINGq---AFSDVTFSVE--------GRLVHAHRCILAARSLFFRKFFcgaaadqaaappgallldhlsp 74  Japanese rice
Q5D0W8        35 RRLSDNLAAAFRSPedfaFLADARIAVPggg---ggGGDLRVHRCVLSARSPFLRGVFarraaaaaggg----------- 100 long-grained rice
20138944      47 QLLSNSFESVFDSPd--dFYSDAKLVLSd-------GREVSFHRCVLSARSSFFKSALaaakkekdsn------------ 105 thale cress
Q9SZI3        49 KLLSNCLESVFDSPe--tFYSDAKLVLAg-------GREVSFHRCILSARIPVFKSALatvkeqks-------------- 105 thale cress
Q5ICL9        94 --------------------kkpkyqmKDLLPYGn----VGREAFLHFLSYIYTGRLkpfpi---evstCVDSVCAHDSC 146 thale cress
Q8L746        98 -------------------tekpkyqlREMLPYGa----VAHEAFLYFLSYIYTGRLkpfpl---evstCVDPVCSHDCC 151 thale cress
XP_002992598 105 ---------------------qqrvdlAELAGGTg---kIGRQALMIVLGYFYGGKFqrieee-csgvtCMDSQCPHVAC 159 Selaginella moe...
XP_001778211  58 -------------------nrklelefSTIVEDGk----IGYDAFMAVMSYVYSGKMelwl----tgiaCYDSTCVHITC 110 Physcomitrella ...
XP_001757508  65 -------------------ntqpkpsiPQVISVGi----VGYDVFMTLLQFLYSGSFqfsaq--ssgrlCQDKSCWHTHC 119 Physcomitrella ...
XP_002986952  61 ----------------------qdipgRPPIPVGi----VGYDVFMLMLQFLYSGQLslvpp---hptgCKEGACWHVYC 111 Selaginella moe...
Q0JJ01       146 -----------gggggertggrprykmEELVPGGr----VGRDAFLSLLGYLYTGKLrpapd---dvvsCADPMCPHDSC 207 Japanese rice
Q75HA6        98 ------------------agdkpqldlDGLVPGGr---hIGRDALVAVLSYLYTGRLrsapp---eaaaCLDDGCSHDAC 153 Japanese rice
A2CIR7        75 rspsggasassprgaggsaaaaaaatpGAVIPVSs----VSYEVFLLLLQFLYSGQVslvpqkgeprpgCGERGCWHTHC 150 Japanese rice
Q5D0W8       101 -----------------gedgserlelRELLGGGgeeveVGYEALRLVLDYLYSGRVgdlpk---aaclCVDEDCAHVGC 160 long-grained rice
20138944     106 ------------------ntaavklelKEIAKDYe----VGFDSVVTVLAYVYSSRVrpppk---gvseCADENCCHVAC 160 thale cress
Q9SZI3       106 -------------------sttvklqlKEIARDYe----VGFDSVVAVLAYVYSGRVrsppk---gasaCVDDDCCHVAC 159 thale cress
Q5ICL9       147 KPAIDFAVELMYASFVFqIPDLVSSFQRKLRNYV 180 thale cress
Q8L746       152 RPAIDFVVQLMYASSVLqVPELVSSFQRRLCNFV 185 thale cress
XP_002992598 160 WPVIEFLLELLFVGSLFqVSDLKSMAQDRLLRLL 193 Selaginella moellendorffii
XP_001778211 111 RPIIDHVLEVLQLSLLLnLPEVTTVAEQHLIDHL 144 Physcomitrella patens
XP_001757508 120 SAAVKFGLDILNAAVFFgVEQLSAITQNHLASMA 153 Physcomitrella patens
XP_002986952 112 RSAVDFALEALHAAQVFsIEQLSILVQRELAGIA 145 Selaginella moellendorffii
Q0JJ01       208 PPAIRFNVEQMYAAWAFkITELISLFQRRLLNFV 241 Japanese rice
Q75HA6       154 RPAIDFVVESTYAASGFqISELVSLFQRRLSDFV 187 Japanese rice
A2CIR7       151 AAAVDLALDTLAAARSFgVEELALLTQKQLAGMV 184 Japanese rice
Q5D0W8       161 HPAVAFMAQVLFAASTFqVAELTNLFQRRLLDVL 194 long-grained rice
20138944     161 RPAVDFMLEVLYLAFIFkIPELITLYQRHLLDVV 194 thale cress
Q9SZI3       160 RSKVDFMVEVLYLSFVFqIQELVTLYERQFLEIV 193 thale cress
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