Conserved Protein Domain Family
TypA_BipA

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TIGR01394: TypA_BipA 
GTP-binding protein TypA/BipA
This bacterial (and Arabidopsis) protein, termed TypA or BipA, a GTP-binding protein, is phosphorylated on a tyrosine residue under some cellular conditions. Mutants show altered regulation of some pathways, but the precise function is unknown. [Regulatory functions, Other, Cellular processes, Adaptations to atypical conditions, Protein synthesis, Translation factors]
Statistics
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PSSM-Id: 273597
Aligned: 14 rows
Threshold Bit Score: 993.346
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CAC44318         7 IRNVAIVAHVDHGKTTIVDGMLKQAGafAAHQ-LEGVDDRMMDSNDLEREKGITILAKNTAVKYHPkdggdvITINIIDT 85  Streptomyces ...
P72749           5 IRNVAIIAHVDHGKTTLVDALLKQSG--IFRE-GEDVPVCVMDSNDLERERGITILSKNTAVRYQD------TLINIVDT 75  Synechocystis...
CAB72532         4 IRNIAVIAHVDHGKTTMVDELLKQSG--TFSE-REQISERVMDSNDIEKERGITILSKNTAINYKG------TKINIIDT 74  Campylobacter...
TIGR:At2g31060  59 LRNVAVIAHVDHGKTTLMDRLLRQCG-------ADIPHERAMDSINLERERGITISSKVTSIFWKD------NELNMVDT 125 thale cress
WP_002229479     4 IRNIAIIAHVDHGKTTLVDQLLRQSG--TFRA-NQQVDERVMDSNDLEKERGITILAKNTAIDYEG------YHINIVDT 74  Neisseria men...
WP_000815077    14 LRNIAIIAHVDHGKTTLVDKLLQQSG--TLES-RGDVEERVMDSNDIEKERGITILAKNTAINWND------YRINIVDT 84  Vibrio cholerae
WP_010887841     3 YRNIAIIAHVDHGKTTLVDGLLKQTL--ELKH-GEEIAERAMDSNDLERERGITILAKNTAVEYNG------VKINIVDT 73  Deinococcus r...
WP_010964991     9 IRNIAIIAHVDHGKTTLVDALLRQSH--VFRA-NEKVEERVMDSNDLEKERGITILSKNTSLMHDG------IKINIVDT 79  Clostridium a...
WP_000164110     8 IRNIAIIAHVDHGKTTLVDELLKQSE--TLDA-RTELAERAMDSNDIEKERGITILAKNTAVAYNG------TRINIMDT 78  Streptococcus...
WP_005874524    34 IRNIAIIAHVDHGKTTLVDKMLLAGK--LFRDdKAAEVDTFLDSNDLERERGITILSKNVSIRYKG------CKINIIDT 105 Porphyromonas...
CAC44318        86 PGHADFGGEVERGLSMVDGVVLLVDASEGPLPQTRFVLRKALSQRLPIILCINKTDRPDARIDEVVNETYDLFLDLDADE 165 Streptomyces ...
P72749          76 PGHADFGGEVERVLGMVDGCVLIVDANEGPMPQTRFVLKKALEKGLRPLVVVNKIDRPRADPNTAVDKVFDLFVELGADD 155 Synechocystis...
CAB72532        75 PGHADFGGEVERVLKMIDGVLLLVDAQEGVMPQTKFVVKKALSLGLKPIVVINKIDKPAADPERVINEIFDLFVALDAND 154 Campylobacter...
TIGR:At2g31060 126 PGHADFGGEVERVVGMVEGAILVVDAGEGPLAQTKFVLAKALKYGLRPILLLNKVDRPSERCDEVESLVFDLFANCGATE 205 thale cress
WP_002229479    75 PGHADFGGEVERVLGMVDCVVLLVDAQEGPMPQTRFVTKKALALGLKPIVVINKIDKPSARPSWVIDQTFELFDNLGATD 154 Neisseria men...
WP_000815077    85 PGHADFGGEVERIMSMVDSVLLIVDAVDGPMPQTRFVTQKAFAHGLKPIVVINKIDRPGARPDWVMDQVFDLFDNLGATD 164 Vibrio cholerae
WP_010887841    74 PGHADFGGEVERVLGMVDGALVLVDAAEGPMPQTRFVLKKAIELGLKPIVVVNKIDRNDARPEEVVNLTFDLMAELGAND 153 Deinococcus r...
WP_010964991    80 PGHADFGGEVERVLKMVDSVLLLVDAFEGPMPQTKFVLKKALELKLKPIVVINKIDKPNARPMEVVDEVLDLFIDLGADE 159 Clostridium a...
WP_000164110    79 PGHADFGGEVERIMKMVDGVVLVVDAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADD 158 Streptococcus...
WP_005874524   106 PGHADFGGEVERVLNMADGCLLLVDAFEGPMPQTRFVLQKAIEMGLKPIVVINKVDKLNCRPSEVQDMVFDLMYSLDASE 185 Porphyromonas...
CAC44318       166 EQIEFPIVYACGRDGVASL--TkpedgTVPsDSTSLEPFFSTILDHIPAPTYDEDAPLQAHVTNLDADNFLGRIALLRVH 243 Streptomyces ...
P72749         156 DQCDFTTLFASGLGGFAKE--S-----LDD-DSEDMKPLFEAILHHVPPPAGDPNKPLQLQVTTLDYSDYLGRIIIGRIH 227 Synechocystis...
CAB72532       155 EQLDFAIVYAAAKNGYAKL--D-----LND-ESDNMEPLFKTILERVPAPSGSDENPLQLQVFTLGYDNFVGKIGIARIF 226 Campylobacter...
TIGR:At2g31060 206 EQLDFPVLYASAKEGWASS--Tyt-kdPPV-DAKNMADLLDAVVRHVQPPKANLDEPFLMLVSMMEKDFYLGRILTGRVT 281 thale cress
WP_002229479   155 EQLDFPIVYASGLSGFAKL--E-----ETD-ESNDMRPLFDTILKYTPAPSGSADETLQLQISQLDYDNYTGRLGIGRIL 226 Neisseria men...
WP_000815077   165 EQLDFQVVYASALNGWATL--V-----EGE-TGENMEPLFQAIVDNVAAPQVDLDGPLQMQISQLDYSSYVGVIGVGRIK 236 Vibrio cholerae
WP_010887841   154 DQLDFPVLYAIAREGKAFK--D-----LEQ-PRDDFKELFDMVLEHIPAPKVDLDSPFQMLVTNLDYSEYLGRIVLGRVA 225 Deinococcus r...
WP_010964991   160 DQLDFPIVYASAKAGIAKL--D-----VDD-ESETMEPLFETIVKYVKGPEGYLDEPLQMLVSTIDSNEYVGRIAIGRVE 231 Clostridium a...
WP_000164110   159 DQLDFPVVYASAINGTSSLsdD-----PAD-QEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLDYNDFVGRIGIGRVF 232 Streptococcus...
WP_005874524   186 DQLDFPTIYGSAKQGWMST--D-----YKH-PTQDIAPLLDAIIRHIPAPEQ-PEGATQMLITSLDYTSYVGRIAVGRVH 256 Porphyromonas...
CAC44318       244 QGELKKGQTVAWMKR----DGSVQNVRISELMMTEALTRKPAEKAGPGDICAVAGIPDIMIGETLADVENPVPLPLITVD 319 Streptomyces ...
P72749         228 NGTVKAGQQAALVKEd----GSIAKGKVSKLLGFEGLNRIELPEASAGYIVAIAGFADANIGETLTCPDEPQALPLIKVD 303 Synechocystis...
CAB72532       227 NGVVKKNQSVMLAKAd----GTKVNGRISKLIGFMGLEKMDIEEAGSGDIVAIAGFEALDVGDSVVDPNNPMPLDPLHIE 302 Campylobacter...
TIGR:At2g31060 282 SGVVRVGDRVNGLRKtdsgSEKIEEAKVVKLMKKKGTTIVSIDAAGAGDIICMAGLTAPSIGHTVASAEVTTALPTVELD 361 thale cress
WP_002229479   227 NGRIKPGQVVAVMNH----DQQIAQGRINQLLGFKGLERVPLEEAEAGDIVIISGIEDIGIGVTITDKDNPKGLPMLSVD 302 Neisseria men...
WP_000815077   237 RGKVKPNQQVTVIGA----DGKKRNGKIGTVLGYLGLQRSETDQATAGDIVAVTGLGELKISDTICDVNALEALPPLSVD 312 Vibrio cholerae
WP_010887841   226 RGTVKKGEFVQLMHK----DGTMTKSRVVQPFTHLGLKRIEVDEVGAGDIVALAGIEDAQIGETIADLAEPEALPIITVD 301 Deinococcus r...
WP_010964991   232 RGSIKKNQQAVLIRR----DGAKENVKISSLFTYEGLKRVEADEVKFGDIAVVSGIPDVNIGETIADASRPEALPFVDID 307 Clostridium a...
WP_000164110   233 RGTVKVGDQVTLSKL----DGTTKNFRVTKLFGFFGLERREIQEAKAGDLIAVSGMEDIFVGETITPTDAVEALPILHID 308 Streptococcus...
WP_005874524   257 RGTLREGQDIMLCKR----DGTMQKQRIKELNTFEGLGRAKADHVDAGDICAIIGLESFEIGETIADANAPEALQAIAID 332 Porphyromonas...
CAC44318       320 EPAISMTIGTNTSPLVGRgatgkgadnkavvkDRKVTARQVKDRLDRELIGNVSLRVLDTERPDAWEVQGRGELALAILV 399 Streptomyces ...
P72749         304 EPTLQMTFSVNDSPFAGQe-------------GKFVTSRQIRDRLNRELETNVALRVEDGESAEQFLVSGRGELHLGILI 370 Synechocystis...
CAB72532       303 EPTLSIVFSVNDGPLAGTe-------------GKHVTSNKIAERLEAEMKTNIAMKYESTGE-GKFKVSGRGELQITILA 368 Campylobacter...
TIGR:At2g31060 362 PPTISMTFGVNDSPLAGQd-------------GTHLTGGRIGDRLMAEAETNLAINVIPGLS-ESYEVQGRGELQLGILI 427 thale cress
WP_002229479   303 EPTLTMDFMVNTSPLAGTe-------------GKFVTSRQIRDRLQKELLTNVALRVEDTADADVFRVSGRGELHLTILL 369 Neisseria men...
WP_000815077   313 EPTVTMTFQVNTSPFAGKe-------------GKFVTSRNILERLEKELVHNVALRVEQTEDPDKFRVSGRGELHLSILI 379 Vibrio cholerae
WP_010887841   302 EPTVSMTFQPNTSPFAGKe-------------GKYVTSRHLNDRLKREVMTNVSLKVEEV-RPDEFVVSGRGELHLSILL 367 Deinococcus r...
WP_010964991   308 EPTLSMFFMVNDSPFAGRe-------------GDFVTSRHLRDRLEKELETNVSLKVEETDSADKFKVSGRGELHLSILI 374 Clostridium a...
WP_000164110   309 EPTLQMTFLVNNSPFAGKe-------------GKWVTSRKVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILI 375 Streptococcus...
WP_005874524   333 EPTMSMLFTINNSPFYGKe-------------GKYVTSRHIHDRLMRELDKNLALRVETTDNADSWLVFGRGVLHLSVLI 399 Porphyromonas...
CAC44318       400 EQMRREGFELTIGKPQVVTKEVEGKTYEPVERMTIDVPEEHMGAVTQLMGVRKGRMDNMSNHGS--GWVRMEFVVPSRGL 477 Streptomyces ...
P72749         371 ETMRREGYEFQVAQPQVIYREVNGQPCEPVEYLVLDVPEAAVGACIERLGQRRGEMQDMQTSVN--GRTQLEFVIPARGL 448 Synechocystis...
CAB72532       369 ENMRREGFEFCMGRPEVIVKVEDGVKTEPFEHLVIDVPEEFSGAVIEKLGKRKAEMKTMAPTGD--GQTRLEFEIPARGL 446 Campylobacter...
TIGR:At2g31060 428 ENMRREGFELSVSPPKVMYKTEKGQKLEPIEEVTIEINDEHVGLVMEALSHRRAEVIDMGPVPGneGRTRLSLTCPSRGL 507 thale cress
WP_002229479   370 ENMRREGYELAVGKPRVVYRDIDGQKCEPYENLTVDVPDDNQGAVMEELGRRRGELTNMESDGN--GRTRLEYHIPARGL 447 Neisseria men...
WP_000815077   380 ENMRREGFELAVSRPEVILKHEDGQLMEPFETVTIDVQEEHQGGIMEKIGMRKGELKDMSPDGK--GRIRMDFVMPSRGL 457 Vibrio cholerae
WP_010887841   368 ETMRREGYEVQVGSPRVIIREIDGEKHEPIEHLVIDVPEQHASTVIGVLGARKGQMVNMEPQGS---RVRVEFKIPARAL 444 Deinococcus r...
WP_010964991   375 ETMRREGFEFQVSKPTVIYKEENGKKLEPIEELTIDVPEEFMGVVMEKLGPRKAELVNMTSAVN--GYTRLEFKIPSRGL 452 Clostridium a...
WP_000164110   376 ETMRREGYELQVSRPEVIVKEIDGIKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGN--GQTRLVFLVPARGL 453 Streptococcus...
WP_005874524   400 ETMRREGYELQVGQPQVIIKEIDGERCEPIELLSINLPEESSSRIIDIVTRRKGEMVMMENKND---RVFMEFHIPSRGI 476 Porphyromonas...
CAC44318       478 IGFRTEFLTQTRGTGIAHSIHEGHEPWF-GTLTTRNNGSLVADRSGAVTAFAMTNLQERGVLFTDPGTEVYEGMIVGENS 556 Streptomyces ...
P72749         449 LGFRGDFIRITRGEGIMNHSFLEYRPMS-GDLETRYNGVMVAFEEGVATFYAMKNAEDRGVFFITPGTKVYKGMIIGEHN 527 Synechocystis...
CAB72532       447 IGFRSQFLTDTKGEGVMNHSFLEFRPFS-GAVEKRNNGALISMENGVALGYSLFNLQERGVLFIEPQTKVYTGMIIGEHS 525 Campylobacter...
TIGR:At2g31060 508 VGYRCVFSSDTRGTGFMHRAFLTYEKYR-GPLGNVRKGVLVSMARGTITAHSLMSLEARGILFVSPGLDSYDGMIIGEHS 586 thale cress
WP_002229479   448 IGFQGEFMTLTRGVGLMSHVFDDYAPVK-PDMPGRHNGVLVSQEQGEAVAYALWNLEDRGRMFVSPNDKIYEGMIIGIHS 526 Neisseria men...
WP_000815077   458 IGFQTEFMTLTSGSGLLYHSFDHYGPHKgGVIGQRVNGVLVSNGTGKALTNALFNLQERGRMFIGHGVEVYEGMVIGIHS 537 Vibrio cholerae
WP_010887841   445 FGFRTQFLSMTQGEGIMSHIFDGYAPWA-GELKTRQNGSLVSMEDGTSFAYSIWKLQDRGNFFIDAGQEVYVGMIVGENA 523 Deinococcus r...
WP_010964991   453 IGFRNEFMTDTKGNGIMNSTLIDYEPFR-GDIPERSRGSIVVFETGVSVVYGLYSAQERGRLFVGAGVDVYEGMVVGECS 531 Clostridium a...
WP_000164110   454 IGYSTEFLSMTRGYGIMNHTFDQYLPLIpGEIGGRHRGALVSIDAGKATTYSIMSIEERGTIFVNPGTEVYEGMIIGENS 533 Streptococcus...
WP_005874524   477 IGLNNAVLTASAGEAVIAHRFLEFQPWK-GEIERRSNGSIIALESGTAYAYALNNLQSRGRFFISPQEEVYAGQVVGEHT 555 Porphyromonas...
CAC44318       557 RADDMDVNITKEKKLTNMRSSSADSFEAIVPPRKLSLEQSLEFCRDDECVEVTPEAVRIRKVNLDARERAR 627 Streptomyces coelicolo...
P72749         528 RPQDIELNVCKTKQLTNHRSATGDELVQLQAPEDMNLERALEYIGPDELVEITPESIRLRKVARKKLVKR- 597 Synechocystis sp. PCC ...
CAB72532       526 RPNDLDVNPIKGKNLTNVRASGSDDAIKLVPPRKLSLERALEWIEEDELVEVTPVNVRVRKRYLDPTQRKR 596 Campylobacter jejuni s...
TIGR:At2g31060 587 RETDLDLNPVKAKELTNIRSAGKDENVKLSPPRLMTLEEAIGYVASDELIEVTPKTIRLRKRCLDVNKRKS 657 thale cress
WP_002229479   527 RDNDLVVNPLKGKKLTNIRASGTDEAVRLTTPIKLTLEGAVEFIDDDELVEITPQSIRLRKRYLSELERRR 597 Neisseria meningitidis
WP_000815077   538 RDNDLTVNPLKGKQLTNVRASGTDDAQVLTPPIIMSLEQALEFIDDDELVEVTPVSIRIRKRFLTENDRKR 608 Vibrio cholerae
WP_010887841   524 REQDMNVNVCKNKKLTNVRSSGADEALTLIPPKRLSLEDALEYIADDELVELTPQSIRLRKKVLNPSFRK- 593 Deinococcus radiodurans
WP_010964991   532 RAEDIEVNVCKKKHLSNTRSSGADDALKLVPIPDMSLEKCLEFIASDELVEITPKSIRMRKKVLDTNLRKK 602 Clostridium acetobutyl...
WP_000164110   534 RENDLTVNITKAKQMTNVRSATKDQTAVIKTPRILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREK 604 Streptococcus pneumoniae
WP_005874524   556 KEGDLCVNVCKSKKLTNMRASGSDDKVSLAPPVVFSLEDALEYIKYDEYVEVTPKSMRMRKIILDETERKR 626 Porphyromonas gingivalis
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