6L1W


Conserved Protein Domain Family
HTH_53
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pfam18606: HTH_53 
Zap helix turn helix N-terminal domain
Zinc-finger antiviral protein (ZAP) is a host factor that specifically inhibits the replication of certain viruses, such as HIV-1, by targeting viral mRNA for degradation. This domain is a helix turn helix domain found at the N-terminal region constituting the top cockpit layer of the protein.
Links
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Statistics
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PSSM-Id: 465819
Aligned: 12 rows
Threshold Bit Score: 98.2413
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6L1W_A          6 EVFCFITKILCAHGGRMTLEELLGEISLPEAQLYELLKAAGPDRFVLLETGDQAG--ITRSVVA 67   house mouse
ELW68824        5 EVCSFITKILCAHKGRMTLEALLGEIVLSEAQLCEVLEVAGPDRFVLLEEGRTTG--VTRSVVA 66  
EHB04413        5 TVCSFLTKVLCAHGGRMLLQDLRGHVELSPARLGDLLQRAGPERFLLQDVEVEAGgaRACRVVA 68  
XP_025837933    5 EVCCFITKILCAHGGRMALDALLQEIALSEAQLREVLEAAGPDRFVLLETGDRAG--VTRAVVA 66  
KFO30136        5 TVCCFITKILCAHGGRLSLDALLEKIELSEAQLLDVLKEAGPDRFVVLETGGRAG--VTRSVVA 66  
XP_007504510    5 TVCDFLTRILCAHGGRMELRELLGHIELSETQVVEVLSEAGPERFMLLDQG--PG--TCPVVLA 64  
XP_003420315    5 TLCSFLTKVLCAHGGRMFLRDLRAHVELSEAQLRAVLRAAGPERFLLQDVAGPEG--LLLQDVA 66  
XP_010714371    5 VVCSYLTETLCAKGGRLGLAELQQYVGLSAQQLQETLQAAGPERFLLLTGSGEAP-----EVLA 63  
XP_003221473    5 AVCSFLTKVLCARGGVAELGELCGEVGLPEAQLKQVLEEAGPERYLRVSRDGAAC--VLALSAA 66  
XP_003582176    5 GVCCFITKILCAHGGRMALEELLHEMQLSEEQLCEVLKEAGPDRFVVLEMGGKEG--VTRSVVA 66  
XP_008247514    5 GVCCFITKILCAHGGRLALDALLQEIGLPKAQLCHELEAAGLERFVVLETGGKDG--VSCSVVA 66  
XP_020733930    5 GVCSFITKILCAHGGRMALEALLREMQLSEAQLCEVLEEAGPDRFVVLEMGGKEG--VTrsvva 66   Odocoileus virginianus texanus
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