Conserved Protein Domain Family
dass

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TIGR00785: dass 
anion transporter
The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Statistics
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PSSM-Id: 273267
Aligned: 11 rows
Threshold Bit Score: 334.312
Created: 7-Oct-2014
Updated: 23-Jan-2015
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P39414    24 PVPAGLENHTWLYFAVFTGVIVGLILEPVPGAVVAMVG-ISIIAILSPWLLfspeqlaqpGFKFTAKslswaVSGFSNSV 102 Escherichia coli K-12
P75763    23 PAPAGLSELAWVLFGIYLAAIVGLVIKPFPEPVVLLIA-VAASMVVVGNLSd-------gAFKTTAV-----LSGYSSGT 89  Escherichia coli K-12
Q57048    23 PAPDGLSLIAWRLLGVYIATIVGLVLKPYGEPVILLAA-IAVSGVIIGNTEga-----keLVKVGNM-----LDGYKSGT 91  Haemophilus influen...
P77405    25 PVPDGMPPQAWHYFAVFVAMIVGMILEPIPATAISFIA-VTICVIGSNYLLfdakeladpAFNAQKQalkwgLAGFSSTT 103 Escherichia coli
AAD05710  22 GAPDGLNPNAWLYFCIFMGMIIGLILEPVPSGLIALSAlVPCIALKIGASS---------EVASANKaiswgLSGYANKT 92  Helicobacter pylori...
Q41364   121 PTPEGVSRNAWQLLAIFLSTIVGIITQPLPLGAVALMG--LGASVLTKTLT------------FSAA-----FSAFGDPI 181 spinach
Q57486    31 PFEPKANSG----LALLAFIAVLWLSEALHVTITALL--VPLLAVALGLVS------------TKQA-----LVGFADPT 87  Haemophilus influen...
AAC06409  22 PFEGNVNKG----IAILLLAAILWITEALPLPVTALL--IPVSGVLLGVFD------------VKTA-----LSYFAHPL 78  Aquifex aeolicus VF5
Q58086    21 SSLPDIYKG----IVILIVAGCLWFFELLPLPVTSLA--IPIMAVFLGIFN------------LKEA-----LTYFAHPI 77  Methanocaldococcus ...
AAD12976  22 QVLFEFPLSVAIMICIFVLAAVFWVAEPIPGYATLILViFLEIIFFANPIGipg----fvFPQNKNPsaavfLSSLADSS 97  Leptospira borgpete...
AAB85290   9 PLPGLRASG-HAALALLVFAVTMWATEAVPLAVTSLI--ILFAQPLIGVES------------FENA-----VIGFANPI 68  Methanothermobacter...
P39414   103 IWLIFAAFMFGTGYEKTGLGRRIALILVKKMGHRTLFLGYAVMFSELILAPVTPSNSARGAGIIYPIIRNLPPLYQSQPn 182 Escherichia coli K-12
P75763    90 TWLVFSAFTLSAAFVTTGLGKRIAYLLIGKIGNTTLGLGYVTVFLDLVLAPATPSNTARAGGIVLPIINSVAVALGSEP- 168 Escherichia coli K-12
Q57048    92 TWLIFTAFTLSSAFVITGLGKRIAYHMIGAMGSTTLRLGYVTMFLDLLLSPATPSNTARSGGIIFPIINSVVVALGSDP- 170 Haemophilus influen...
P77405   104 VWLVFGAFIFALGYEVSGLGRRIALFLVKFMGKRTLTLGYAIVIIDILLAPFTPSNTARTGGTVFPVIKNLPPLFKSFPn 183 Escherichia coli
AAD05710  93 VWLVFVAFILGLGYEKSLLGKRIALLLIRFLGQTPLGLGYAIGLSELCLAPFIPSNSARSGGILYPIVSSIPPLMGSTP- 171 Helicobacter pylori...
Q41364   182 PWLIALAFFFARGFIKTGLGNRIAYQFVKLFGSSSLGLGYSLVFSEALLAPAIPSVSARAGGIFLPLVKSLCIACGSNVg 261 spinach
Q57486    88 IFLFFGGFSLATALHIQKLDKLIANKIMALARG-NLFIAVIYLFLITAFLSMWMSNTA-TAAMMLPLAMGILSQLDREK- 164 Haemophilus influen...
AAC06409  79 IFLFFGGFVLAVALSKYQIDEYIAHKIVSVAQG-KFLPSVFLLMLATSLISMWISNTS-TTAMMLPLALGILAGVRETE- 155 Aquifex aeolicus VF5
Q58086    78 IFLFLGGFMLAQALKNHNLDKFIAYKLLNYGKD--FKTTCFLMFLSAYFLSMWISNTS-ATLILLPIALGL--LH-KKTg 151 Methanocaldococcus ...
AAD12976  98 IILFLGGFVLAKACVKTGLDRFFANRIIRKFGV-KSHQVLLGFMFTTGFISMWMSNTA-TTSMMIALSFPLLRVLPEKE- 174 Leptospira borgpete...
AAB85290  69 LFLMIGGFIMAEAIRKSGLAQRFTYYLLGRLGT-SPERGLFVSIFSTGLLSAWIENVV-AFAMLLPIIKEIVDIMGCSEp 146 Methanothermobacter...
P39414   183 DSSSRSIGSYIMWMGIVADCVTSAIFLTAMAPNLLLIGLMKSASHATLSWGDWFLGM-LPlSILLVLLVPWLAYVLYPPV 261 Escherichia coli K-12
P75763   169 EKSPRRVGHYLMMSIYMVTKTTSYMFFTAMAGNILALKMINDILHLQISWGGWALAAgLP-GIIMLLVTPLVIYTMYPPE 247 Escherichia coli K-12
Q57048   171 EKSPKKAGRYLMMNVYMVVKTTSYIFLTAMAPNALALSLMAPILGFETTWIKWFLAAsVP-GLLCLFLIPLICYWVSPPE 249 Haemophilus influen...
P77405   184 DPSARRIGGYLMWMMVISTSLSSSMFVTGAAPNVLGLEFVSKIAGIQISWLQWFLCF-LPvGVILLIIAPWLSYVLYKPE 262 Escherichia coli
AAD05710 172 SNNPDKIGAYLMWVALASTCITSSMFLTALAPNPLAMEIATKMGVNEISWFSWFLAF-LPcGVVLILLVPLLAYKTCKPT 250 Helicobacter pylori...
Q41364   262 DGTERKLGAWLMLTCFQTSVISSSMFLTAMAANPLSATLTFNTIGKAIGWMDWAKAAfVP-GLVSLIVVPLLLYVVYPPE 340 spinach
Q57486   165 ---DHNTYVFVLLGIAYSASIGGMGTLVGSPPNAIVASNLN------LTFSDWLWYG-LPiMIILLPLMIGILYIIFKPK 234 Haemophilus influen...
AAC06409 156 ---REKVFPFVLLGIAYSASVGGIGTLVGSPPNGIAAGILG------LSFPDWLKFG-IPvFLILFPLLFAILFLVFRPT 225 Aquifex aeolicus VF5
Q58086   152 -----KLRDFLLLGVAYSASIGGIATIIGSPPNAIASSYLD------YGFFSWFKVG-FPiSLLLFLICTLTLYIYFK-K 218 Methanocaldococcus ...
AAD12976 175 -----PFRKALILGIPFAANIGGVGTPIGSPPNIIAMGILRQQ-GIVIPFGTWMFFA-VPlVVVLILFAWILLMKLFP-- 245 Leptospira borgpete...
AAB85290 147 EKGKSNYAKAMILGASFGSLAGGFGTEIGTAPNLMAAAYTS------IPFLNWMIFG-LPlSIAMLLVTWFLLMRIFPSE 219 Methanothermobacter...
P39414   262 LKSGDQvPRWAETELQAMGPLCSREK---RMLGLMVGALVLWIFG-GDYID-----AAMVGYSVVALMLLLRIISWDDIV 332 Escherichia coli K-12
P75763   248 IKKVDN-KTIAKAGLAELGPMKIREK---MLLGVFVLALLGWIFSkSLGVD-----ESTVAIVVMATMLLLGIVTWEDVV 318 Escherichia coli K-12
Q57048   250 LKKVDN-KAIAKKGLEELGPMSFREK---ALSVLFVIALFGWIFSnSLHIN-----ATIVAIIVMVLCIVLSIVTWDDIL 320 Haemophilus influen...
P77405   263 ITHSEEvATWAGDELKTMGALTRREW---TLIGLVLLSLGLWVFG-SEVIN-----ATAVGLLAVSLMLALHVVPWKDIT 333 Escherichia coli
AAD05710 251 LKGSKEvSLWAKKELESMGRFSLKEI---LMLSLTLLALLGWIFGkSLGLH-----ASATALIVMVLMAFCKIVSYEDII 322 Helicobacter pylori...
Q41364   341 IKSSPDaPRLAKEKLDKMGPMTKNES---IMAVTLLLTVGLWVFGgKLGVD-----AVTAAILGLSVLLITGVVTWKECL 412 spinach
Q57486   235 LHLNFEqTFEN-IEMNPMRILTFIIFpviALTWIFSGKINPFISGlLGLQKniasfDSIVALLAAIVICSTGVASWKQIQ 313 Haemophilus influen...
AAC06409 226 SDLKVErVQEIKFEFTPQRVLVLLIFlftALAWIFSKKIAPi----FEVKKy---fDTVVALLAVVALFIFRLLDWRDVK 298 Aquifex aeolicus VF5
Q58086   219 WIPKEDiAIQARMELSRNAYKLLVIFvliASLWIISDYLSEi----FNVQYf----DSVIAIFAIILLFVFNLVEVNDFK 290 Methanocaldococcus ...
AAD12976 246 --QKDSlDLVVEFQEPERGMKSFSFR---VTSMIFLGTVVLWFTEnLHGVP-----AGVVALLPLILFPMFGILNEKDIN 315 Leptospira borgpete...
AAB85290 220 VRALENgDALIGERIRMMGSMSRDEK---LSAGILLFAILLWVTAgFTGIN-----SYSVSLIAAVMFIFAGVITWKDAQ 291 Methanothermobacter...
P39414   333 SNKAAWNVFFWLASLITLATGLNNTGFISWFGKLLAGSL--SGYSpTMVMVALIVVFYLLRYFFASATAYTSALAPMMIA 410 Escherichia coli K-12
P75763   319 KNKGGWNTLIWYGGIIGLSSLLSKVKFFEWLAEVFKNNLafDGHG-NVAFFVIIFLSIIVRYFFASGSAYIVAMLPVFAM 397 Escherichia coli K-12
Q57048   321 KSKGAWNTLVWYGGIIGMSGLLEKSGFFKWLANTLSTILqfEGHG-MMALIVILTLSVSVRYLFASGGAYVAAMVPVFAT 399 Haemophilus influen...
P77405   334 RYNSAWNTLVNLATLVVMANGLTRSGFIDWFAGTMSTHL--EGFSpNATVIVLVLVFYFAHYLFASLSAHTATMLPVILA 411 Escherichia coli
AAD05710 323 KNKSAFNIFLLLGSLLTMAGGLKNVGFLNFIGNAAQNFLehAHLDpLIAVLFIVALFYLSHYFFASITAHVSALFALFVG 402 Helicobacter pylori...
Q41364   413 AESVAWDTLTWFAALIAMAGYLNKYGLITWFSENVVKVVggLGLSwQMSFGVLVLLYFYSHYFFASGAAHIGAMFTAFLS 492 spinach
Q57486   314 SN-TDWGVLMLFGGGLTLSAVLKDSGASKILADSIVFMI--DGQH-FYLIGLLVAAFIIFLTEFTSNTASAALLVPIFIS 389 Haemophilus influen...
AAC06409 299 EG-VSWGTLLLFGGGIALSGIMKKTGTAKFISQELVDVL--HGLP-TFLFLLTIVLFVIFLTELMSNTATTALIAPILFS 374 Aquifex aeolicus VF5
Q58086   291 KI--DWGTLILFGGALCLGGVIVKSGANTFLSEKLIAIL---GNLtPIVLLFLVVTITIILTNFISNTGLTGIIVPILFG 365 Methanocaldococcus ...
AAD12976 316 SL--DWSVLILISGGIGIGVGFQQSGMGPWFSGILKHIA---KPEyAISVLFFLCVLTLLLSTFMSNTAATNLLVPFAFP 390 Leptospira borgpete...
AAB85290 292 KN-IDWGLVVFFGGALSLGSALLKTGAAAWIIDKLVGMLg--SDPsTVIVMLVLMAVAVIITQVMSNIALSAILVPLSVT 368 Methanothermobacter...
P39414   411 AALaMP---EIPLPVFCLMVGAAIGLGSILTPYATGPSPIYYGSGYLPTADYWRLGAIFGLIFLVLLVITGLL-W 481 Escherichia coli K-12
P75763   398 LAN-VS---GAPLMLTALALLFSNSYGGMVTHYGGAAGPVIFGVGYNDIKSWWLVGAVLTILTFLVHITLGVWwW 468 Escherichia coli K-12
Q57048   400 VGH-VT---GAPTELLALGLVFANSYGGSVTHYGGGPGPIAFGAGYNDIKSWWITGAIIAFGSLIIHLTIGMAwW 470 Haemophilus influenzae R...
P77405   412 VGKgIP---GVPMEQLCILLVLSIGIMGCLTPYATGPGVIIYGCGYVKSKDYWRLGAIFGVIYISMLLLVG---W 480 Escherichia coli
AAD05710 403 IGShIQ---GVNLQELSLFLMLSLGIMGILTPYGTGPSTIYYGSGYIQSKDFWKWGFIFGFLYLIVFLSVCAP-W 473 Helicobacter pylori J99
Q41364   493 VAS-AL---GTPPFLAAIVLSFLSNLMGGLTHYGIGSAPVFYGANYVPLPQWWGYGFLISIVNLIIWLGVGGLwW 563 spinach
Q57486   390 IAQ-SL---GMPEIGLALIIGIGASCA-FMLPVATPPNAIVFGSGQVKQSEMVKVGFLLNLVCVVVIATMGYMfW 459 Haemophilus influenzae R...
AAC06409 375 TAQ-MI---GKPPEMLVIPAAVAASCA-FMLPVATPPNAIVYGTGYIKQSQMMRVGLILNIVFSIVLAAFFTVyV 444 Aquifex aeolicus VF5
Q58086   366 VSL------GIPKEILILAVGMSASCS-FILPVGTPPNAIVYSEG-VKKEEMMKIGMILSILSAAVITLYSILyL 432 Methanocaldococcus janna...
AAD12976 391 FSAiLFpgsNVYLLEVCLGIALSASLA-MSLPVSTPPNAIAYSVGGIEIKDMICAGLPIGIFGLIVVLSSYFAfF 464 Leptospira borgpetersenii
AAB85290 369 LAS-AQh-qPIGVYAVPVAIACSLSFM---LPMADPTVAMAYGSGYVKLRDIPRAGIPIIAVGIILTVLVITTlA 438 Methanothermobacter ther...
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