Conserved Protein Domain Family
2A0308

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TIGR00911: 2A0308 
L-type amino acid transporter
[Transport and binding proteins, Amino acids, peptides and amines]
Statistics
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Structure
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TIGR00911 is classified as a model that may span more than one domain.
TIGR00911 is the only member of the superfamily cl30119
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P50276     1 MSEGRTFLSQLNVFnkeNYQFSSSTTKKEVSNSTVDAdngasdfeAgqqfatelDQGEKQLGILSCIGLICNRMLGTGVF 80  Saccharomyces cerev...
AAF03694   1 MAGSGPKRRAAAATlpaNEKEERQARERMLAARGADGae-----gE--------VTLQRNITLLNGVAIIVGTIIGSGIF 67  cattle
CAA73254   1 MAADSVKRRQSGASk--TEEEDRQAAEKMLHQNGNAEpksg-dggA--------VELQRTITLVNGVAIIVGTIIGSGIF 69  African clawed frog
CAB69072   1 MEKGARQRNNTAKN---HP-----GSDTSPEAEASSGg------gG--------VALKKEIGLVSACGIIVGNIIGSGIF 58  house mouse
BAA77220   1 MVRKPVVATISKGG---YLQGNMSGRLPSMGDQEPPGq------eK--------VVLKKKITLLRGVSIIIGTVIGSGIF 63  house mouse
AAB39265   1 MGKSKKENKDSNAT---------------------ES-----------------VALKKEVSVLQGVSIVVGVIIGSGIF 42  Schistosoma mansoni
P50276    81 AVSSTIYTLCGSVGLALIMWAVGAIIAISGLYVYMEFGTAIPKNGGEKNYLEAIFRKPKFFITCMYAAYIFFLGWAAGNS 160 Saccharomyces cerev...
AAF03694  68 VTPTGVLKEAGSPGLALVVWAVCGVFSIVGALCYAELGTTITKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVA 147 cattle
CAA73254  70 VTPTGVLREAGSPGLSLLVWAVCGLFSIVGALCYAELGTTISKSGGDYAYVLEVYGALPAFLKLWVELLIIRPSSQYIVA 149 African clawed frog
CAB69072  59 VSPKGVLENAGSVGLALIVWIVTGIITAVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIA 138 house mouse
BAA77220  64 ISPKGILQNTGSVGMSLVFWSACGVLSLFGALSYAELGTSIKKSGGHYTYILEVFGPLLAFVRVWVELLVIRPGATAVIS 143 house mouse
AAB39265  43 VSPVGVLKHTKSVGLSFIMWAVTGLFSTLGAIVYAELGVTIPRSGGEYVYILQTFGPLLAFLAFWITFVVIGSASCAANA 122 Schistosoma mansoni
P50276   161 INTAIMFLT--AADTEVTKWNQRGIGVAVVFFAFLINSLNVKIGLYLQNILGIFKIGIVLFISITGWVALGGglkDGYQS 238 Saccharomyces cerev...
AAF03694 148 LVFATYLLKpiFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFIQIGK---GDVAN 224 cattle
CAA73254 150 LVFATYLLKpvFPTCPVPDDAAKIVACLCILLLTAINCYSVKAATRVQDAFAAAKLLALFLIIILGFVQLGK---GGVED 226 African clawed frog
CAB69072 139 LTFSNYVLQplFPTCFPPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICK---GEFFW 215 house mouse
BAA77220 144 LAFGRYILEpfFIQCEIPELAIKLVTAVGITVVMVLNSTSVSWSARIQIFLTFCKLTAILIIIVPGVIQLIK---GQTHH 220 house mouse
AAB39265 123 LIFAQYILRpvYMDCVTPTIVIRTVAVLGLLLLCFVHCFSVKLATKVAVVFTACKVTALLIIIGFGLYYLGK---GNVES 199 Schistosoma mansoni
P50276   239 HNFRNAFEGTEtATAYGIVNALYSVIWSFVGYSNVNYALGEVKNPVRTLKIAGPTSMVFLAIIYIFVNIAYFAVVPKDKL 318 Saccharomyces cerev...
AAF03694 225 LDPKSSFEGTK-LDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLTPEQM 303 cattle
CAA73254 227 LKPERSFEGTS-TNVGQWVLALYSGLFAYGGWNYLNFVVEEMIEPYKNLPRAIIISMPIVTLVYVLTNLAYFTTLTPEQM 305 African clawed frog
CAB69072 216 LEPKNAFENFQePDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANIAYVTAMSPQEL 295 house mouse
BAA77220 221 F--KDAFSGRD-TSLMGLPLAFYYGMYAYAGWFYLNFITEEVDNPEKTIPLAICISMAIITVGYVLTNVAYFTTISAEEL 297 house mouse
AAB39265 200 F--KNAFEDSE-KSPGELALGFYQGFWAFSGWNYLNFLTGEVKNPGRTLPIVIILSLTTVTFIYILTNVAYLAVLSPLEV 276 Schistosoma mansoni
P50276   319 ISSk--LILAADFFDIVFGgQAKRAAAALVGLSALGNVLSVIFSQGRIIQQLGREGVLPFSNFFASSKPFNSpmvgLFQH 396 Saccharomyces cerev...
AAF03694 304 LTS---EAVAVDFGNYHLG-VMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGAREGHLPSILSMIHPRLLTP----VPSL 375 cattle
CAA73254 306 LNS---EAVAVDFGNYHLG-VMAWIIPVFVGLSCFGSVNGSLFTSSRLFFVGAREGHLPSLLAMIHPRLLTP----MPSL 377 African clawed frog
CAB69072 296 LAS---NAVAVTFGEKLLG-VMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTP----IPAL 367 house mouse
BAA77220 298 LQS---SAVAVTFSERLLG-KFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSMIHVHKHTP----LPAV 369 house mouse
AAB39265 277 LASegsTAIAVSFASRTMG-VVGLVMPALVGASVFGSINGEVFSISRLAFTAGEEGHMPALLSMVNIDRLTP----IPSI 351 Schistosoma mansoni
P50276   397 FIVCTVTILAPPPGDAYLLVQnLISYPMNIINFAISAGLLWIYWQRRqgkiEWNPP-IKAGVFVTGFFTLSNLYLIIAPY 475 Saccharomyces cerev...
AAF03694 376 VFTCIMTLLYAFSKDIFSVIN-FFSFFNWLCVALAIAGMLWLRYQKP----ELERP-IKVHLALPVFFILACLFLIAVSF 449 cattle
CAA73254 378 IFTCAMTLLYAFSNDIFSVIN-FFSFFNWLCVALAIIGMMWLRYKKP----ELERP-IKVNILLPIFFILACIFLIVVSF 451 African clawed frog
CAB69072 368 LFTCLSTLLMLVTSDMYTLIN-YVGFINYLFYGVTVAGQIVLRWKKP----DIPRP-IKVSLLFPIIYLLFWAFLLIFSL 441 house mouse
BAA77220 370 IVLHPLTMVMLFSGDLYSLLN-FLSFARWLFMGLAVAGLIYLRYKRP----DMHRP-FKVPLFIPALFSFTCLFMVVLSL 443 house mouse
AAB39265 352 LIVVTLSVIFQMFDDILYLIE-LTGFAFSVMSAMAVCSLLYIRRTNP----EMNTSgFKLPIFFPVLYLIVDIAIGILAI 426 Schistosoma mansoni
P50276   476 VPPSNGESVYssmpyWIHCVIAWGIFFFGgvyyvVWAQLLPRWGHYKLVSKDVLGEDGFWRVkIAK 541 Saccharomyces cerevisiae S288c
AAF03694 450 WKTPVECGIG-----FTIILSGLPVYFLG-----VWWRDKPKWLLQSIFSTTVLCQKLMHVV-PQE 504 cattle
CAA73254 452 YMTPVECGIG-----FIIILTGVPVYFFG-----VWWQNKPDWILHGIHSSTALLQKVMEAV-PQE 506 African clawed frog
CAB69072 442 WSEPVVCGIG-----LAIMLTGVPVYFLG-----VYWQHKPKCFNDFIKSLTLVSQKMCVVVyPQE 497 house mouse
BAA77220 444 YSDPFSTGVG-----FLITLTGVPAYYLF-----IVWDKKPKWFRRLSDRITRTLQIILEVV-PED 498 house mouse
AAB39265 427 YQKPTDCAVS-----LGVMLLGVPVYLFG-----VVWKNKPRSMRSLIYGVTITLQKVLKVVeQEK 482 Schistosoma mansoni
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