Conserved Protein Domain Family
TIM21

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pfam08294: TIM21 
TIM21
TIM21 interacts with the outer mitochondrial TOM complex and promotes the insertion of proteins into the inner mitochondrial membrane.
Statistics
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PSSM-Id: 311963
Aligned: 13 rows
Threshold Bit Score: 176.713
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P53220        67 QVKSASTFTFSGILVIGAVGISAIVIYLILSELFSPSGDTQLFNRAVSMVEKNKDIRSLLqcddgitgKERLKAYGELIT 146 Saccharomyces c...
Q6FMZ2        43 KLKALTSFTASSLLVVGGVGVSGVVLYLILSELFSPSGDTMLFNRAVTLVEDNEEVRKLLqcndssfkKERLKAYGELVT 122 Nakaseomyces gl...
Q6BVK1       100 RIGRAFTFSLSSVIVLGATCISVLVVYLILSELFLPSGDTRTFNKAVRMLESNELAHEALgf----kkGQRVKAHGEQHA 175 Debaryomyces ha...
Q6CAQ9        99 KIGVFFQLSWYLGIILAALGLFGLVWYYLIMELVMPSGDVRIFNRAFKEIEKNEDVMRVL--------GGQLSSMGEGGG 170 Yarrowia lipoly...
O94618        62 KAYRTSANIGNFSIVIFGGGVFGLIIYALVTSIW--KGEAHYGDEAFELLKANEECRYVF--------GDHMKALGEATH 131 Schizosaccharom...
Q7S8S5        82 KAGRAVQQTFNFGLVILGVVLTGGIAYLLFTDVFSPESKTAYFNRAVDRIRADPRCVALLsp----gdPKKIAAHGEETH 157 Neurospora cras...
XP_002647128  79 KVAEKASNTFMYTAVVAGVGLIGAFIYVLAGEFFAQDSPQTIFNKALALVREDGRCQDIF--------GASIAGFGEETS 150
Q28HE3        87 KVKEAGRDFTYFIVVLIGIGVTGGLFYVVFEELFSSSSPSKIYGEALEKCRSHPEVIGAF--------GEPIKGYGETTR 158 tropical clawed...
Q5U2X7        99 KVKEAGRDVTYLIVVLFGVSITGSLLYTIFKELFSSSSPNIIYGKALGKCRTHPEVISVF--------GEPVKGYGEMSR 170 Norway rat
Q9VMR0        68 KIKENTKTASYTAIIIAGLGVTCVMFFAIFRELFSSESPNNIYADALRRVVEDPRVQDAI--------GAPIKGFGETSR 139 fruit fly
Q7PPN0        66 RVKENTKTASYMGVILLGVGVTGMLFYVIFWELFSSDSPNNIYSEALERVKEEPRVKDAL--------GAPIKGYGEETR 137 Anopheles gambi...
Q75CX4        63 KVRAAATFSASGMLVLGAAGVAGIVLYLILSELFSPSGDTQIFNRAVSTVEGDAVARSLLqcedgvhrSERLKAYGDSVG 142 Eremothecium go...
Q6CW96        63 RIRAFTTFTFSGILVIGATGLAGVVIYLIGAELFSPSGDTQIFNRAVSKVENDEVARRLLkcndtetsTERLKAYGEILT 142 Kluyveromyces l...
P53220       147 NDKWTRNRPIVSTKKLDKEGRTHHYMRFHVES--KKKIALVHLEAKESKQN--YQPDFINMY--VDVPGEKRYYLIKPK 219 Saccharomyces ce...
Q6FMZ2       123 NDRWTRNRPIVSTQKIDKYGKCHHFMRFHLES--KKKLGLVHVEAVDSEQN--YKPNFVSMY--IDIPGEKRFYIIRPK 195 Nakaseomyces gla...
Q6BVK1       176 -DKWARNRPAQSVRTRGADGKDYLFMKFQVESp-SGKYGTVTLEQVDRTF---WSSEFLYIA--LDMPGNKRIYIKEPK 247 Debaryomyces han...
Q6CAQ9       171 -GRWGRNQPPVSKRGIDKYGREHIWMNFYVSG--DINEGRAKLELVQNTDSklSSERFVYRYfvVDIPGHKRIYIAGNA 246 Yarrowia lipolyt...
O94618       132 PLR--RTHGILTSRVWDHHGVEHLVLQFHLIG--NERKGHVFGRLVNVQ----GDYKWEYLF--VDVANYGKIIIFDHT 200 Schizosaccharomy...
Q7S8S5       158 -NKWRRARPIAATVEKDNRGVEHLKMHFHVEG--PRGSGVVGLHLTKQPGH--WEHEYQTFY--VDVRGHQRIYLENKE 229 Neurospora crass...
XP_002647128 151 RGR----RRHVAHHKYEKDGMQRIRVLFHVKG--DRDEGIAQAEMEQRD----GDWEWRFLYveNKRRPKTTHVLIDNR 219
Q28HE3       159 RGR----RQHVSHMEYVKDGIKCMRLKFYIEGlePRKQGTVHTEVKENPES--GKYEFQYIFveIDTYPRRTIVIEDNR 231 tropical clawed ...
Q5U2X7       171 RGR----RQHVSFTEYANNGLKRIRVKFYIEGsePGKQGTVHAEVEENPRS--GQFDFRYIFv--DVAPKRSIVVEDNR 241 Norway rat
Q9VMR0       140 RGR----RQHVAHSSYERNGKPHMRMQFYVQG--LRNKATVQLESRRSDS---GKLEYRYLFvqLDHYPRTTIILEDNR 209 fruit fly
Q7PPN0       138 RGR----RTRVAHTQYVKDGVEHIRMQFHVQG--FRNRGTVHLEKRKTDA---GGYEYRYLFvqLDYNPHSPIILEDNR 207 Anopheles gambia...
Q75CX4       143 DDRWTRNRPISSTRRLDASGREHYYMRFHVET--GRRRGVVSLEAQQSDDS--YQPEFVRMY--LDVPGEKRHYLIRPE 215 Eremothecium gos...
Q6CW96       143 DDRWTRNRPISSTRRIDKEGKEHYLMRFHVES--KQKMGIVHVEAKESDVN--YQPDFVSMY--LDIPGEKRHYLIKPK 215 Kluyveromyces la...
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