Conserved Protein Domain Family
tfb2

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TIGR00625: tfb2 
Transcription factor tfb2
All proteins in this family are part of the TFIIH complex which is involved in the initiation of transcription and nucleotide excision repair.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Statistics
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PSSM-Id: 273180
Aligned: 3 rows
Threshold Bit Score: 739.028
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
AAB68240   9 SVTQYLEEIPQQVQnrLYTSPATCLAIYRILPPLAKFFIMAMVFNENEVPLLDLDKWVNSNGKLQFQNAIKSMKSLHLLI 88  baker's yeast
CAA18666   8 SINDFLEQLPNHAR--LYQKPAACLAVFRLLPILARQYVMSMLFNPMPVALSDFDLWIKLSSKVYQSESFNKLVRMHIFQ 85  fission yeast
Q92759    18 NLQEFLGGLSPGVLdrLYGHPATCLAVFRELPSLAKNWVMRMLFLEQPLPQAAVALWVKKEFSKAQEESTGLLSGLRIWH 97  human
AAB68240  89 PNKss-gtLMINLNPTFKISLRNALTGGEVQNSFGVVVEEN---VVSLDLLDEYSANKWETILHFMVGTPLAKIPSEKVL 164 baker's yeast
CAA18666  86 FDG-----QYITLNSEFRKQFITALTGGGNHNSFGVPCTDEdkhLVTVDFLDAYAKETWETILHFMVGTPEAKFPGEGVL 160 fission yeast
Q92759    98 TQLlpgglQGLILNPIFRQNLRIALLGGGKAWSDDTSQLGPdkhARDVPSLDKYAEERWEVVLHFMVGSPSAAVS-QDLA 176 human
AAB68240 165 NLLKHSKLMEEVnsTGEFKITNEGFQFLLQEINSQLWTLLLQYLKMIETSKMDLVDVLHFIFMLGALEVGKAYKIDALSE 244 baker's yeast
CAA18666 161 SLLKRGGLMSGP--KNQLRITRAGFQFLLQDINAQIWTLLLDYLKLSEDTHMDPVQVLHFLFMLGSLDLGRAYSVDFLTD 238 fission yeast
Q92759   177 QLLSQAGLMKSTepGEPPCITSAGFQFLLLDTPAQLWYFMLQYLQTAQSRGMDLVEILSFLFQLSFSTLGKDYSVEGMSD 256 human
AAB68240 245 TQRIMLQDMRDYGLVFQKHSNDSIFYPTKLALMLTSDTKTIRSASNAMDsvlrqnreepsvnedgangksttdittsDDL 324 baker's yeast
CAA18666 239 TQQIMLEDLREYGLVYQRKITSKRFYPTRLATGLTTDYRSLHGKQSEND----------------------------DDK 290 fission yeast
Q92759   257 SLLNFLQHLREFGLVFQRKRKSRRYYPTRLAINLSSG---VSGAGGTVH----------------------------QP- 304 human
AAB68240 325 nkaglknqdipdGSLIVETNFKIYSYSNSPLQIAVLSLFVHLKARFVNMVLGQITRESIRRALTNGITADQIIAYLETHA 404 baker's yeast
CAA18666 291 ------------GFIIVETNYRLYAYTSSPLQIAIIGLFANLRARFSNLVVGVITRDSIRRALMNGIAAEQIITYLTTHA 358 fission yeast
Q92759   305 ------------GFIVVETNYRLYAYTESELQIALIALFSEMLYRFPNMVVAQVTRESVQQAIASGITAQQIIHFLRTRA 372 human
AAB68240 405 HPQMRrlaeeklekkleldpnckEPLQVLPPTVVDQIRLWQLELDRVITYEGSLYSDFETSQEYNLLSKYAQDIGVLLWK 484 baker's yeast
CAA18666 359 HPQMR------------------SNVPLLPPTLVDQIYLWELEKNRLRATPGILFRDFLTDSGFDQAVEYAKELGVLVWD 420 fission yeast
Q92759   373 HPVMLk------------------QTPVLPPTITDQIRLWELERDRLRFTEGVLYNQFLSQVDFELLLAHARELGVLVFE 434 human
AAB68240 485 DDKKKKFFISKEGNSQVLDFAKRKLK 510 baker's yeast
CAA18666 421 SSLKRMFFITTTGAQPMIAYLKRRAV 446 fission yeast
Q92759   435 NSAKRLMVVTPAGHSDVKRFWKRQKH 460 human
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