Conserved Protein Domain Family
MIT_spastin
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cd02679: MIT_spastin 
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This MIT domain sub-family is found in the AAA protein spastin, a probable ATPase involved in the assembly or function of nuclear protein complexes; spastins might also be involved in microtubule dynamics. The molecular function of the MIT domain is unclear.
Links
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Statistics
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PSSM-Id: 239142
Aligned: 17 rows
Threshold Bit Score: 89.6443
Created: 23-May-2005
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q9UBP0    116 VRVFHKQAFEYISIALRIDEDekaGQKEQAVEWYKKGIEELEKGIAVIv-----------------TGQGEQCERARRLQ 178 human
XP_417098  18 INEEYTKAFIFINKGLQADEL---GQKEEARNYYKQGLDHLLQGLSIPsq--------------dpACVGPQWESARQMQ 80  chicken
CAG09018    6 IKDGYDRAFECINKALTADEA---GEKTQALDLYKRGQQHLLRAIVVPsq--------------geECVGSSWESARQMQ 68  Tetraodon nigrovir...
AAL25088   87 LKGYFDLAKEEIDKAVRAEEW---GLADDAISHYQNAQKILAEGISTPvp---------------sYITSSEQEKVKSYR 148 common tobacco
Q8N0X7     16 IREAYKKAFLFVNKGLNTDEL---GQKEEAKNYYKQGIGHLLRGISISsk--------------esEHTGPGWESARQMQ 78  human
AAC06152   52 LKGYFDLAKEEIAKGVRAEEW---GLHDDALLHYRNAQRIMNEATSTPsp---------------sYISSSEKEKVRSYR 113 thale cress
BAD44799   46 LRGYFELAKEEIDKAVRAEEW---GLPDDAAAHYRNALRVMLEAKAARvp---------------dAVSSSERGQVRVYQ 107 Japanese rice
CAG00427    8 LRDQYGQARRSLSGALAAEDA---GDKAKALACYRKAQQHLVQGAEVPtn--------------gdRQKGPAWDTARELR 70  Tetraodon nigrovir...
EAL28520   15 IQAAYKAAMTQVELALDREEQ---EDTQQTIGAYERALEMIEETFAIPvglp-----------deiDAVQTQWNDACSLI 80  Drosophila pseudoo...
NP_910388  22 LRGYFELAKEEIDKAVRAEEW---GLPDDAAAHYRNALRVMLEAKAARvpdavssrsvprggrlgsTRRRSQSGRLRWRN 98  Japanese rice

Q9UBP0    179 AKMMTNLVMAKDRLQLL 195 human
XP_417098  81 QKMKETLQNVRTRLDIL 97  chicken
CAG09018   69 EKMRETLNNITTRLAVL 85  Tetraodon nigroviridis
AAL25088  149 QKLTKWKSQVSERLQTL 165 common tobacco
Q8N0X7     79 QKMKETLQNVRTRLEIL 95  human
AAC06152  114 EKISNWQNQVSERLQAL 130 thale cress
BAD44799  108 EKIAKWQTQVEERLRVL 124 Japanese rice
CAG00427   71 RRMEATLGAVNTHLSDL 87  Tetraodon nigroviridis
EAL28520   81 QKLKSAKTEVSYRVKVL 97  Drosophila pseudoobscura
NP_910388  99 DSGCSARGVVVTNNPVN 115 Japanese rice
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