4YAH,1XS5,4GOT,4K3F


Conserved Protein Domain Family
Lipoprotein_9

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pfam03180: Lipoprotein_9 
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NlpA lipoprotein
This entry represents bacterial lipoproteins that belong to the NlpA family. It contains several antigenic members, that may be involved in bacterial virulence. This entry includes the D-methionine binding lipoprotein MetQ, which is the substrate-binding component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system. Other members of this family, such as NlpA, have been identified as putative substrate-binding components of ABC transporters. NlpA, is an inner-membrane-anchored lipoprotein that has been shown to have a minor role in methionine import.
Statistics
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PSSM-Id: 427184
Aligned: 29 rows
Threshold Bit Score: 183.619
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4YAH_X  33 IKVGVIVGAEQQVAE--VAQKVAKDKYgLDVELVTFNDYVLPNEALSKGDIDANAFQHKPYLDQQLKDrGYK-LVAVGNT 109 Escherichia coli K-12
Q9I1C9  26 LKIGTT-AAFAPPLE--VAVSEAGKQG-LKVELVEFSDWNAPNITLAQGDIDANYFQHVPFLENANRE-GGFqLKPFAPG 100 Pseudomonas aeruginosa
Q9CIN7  40 VKIGIMTGTKEDDSIwqTVSKTAKDKYgITLKFTHFTDYTQPNTALKNGDIDLNAFQHYAFLKAWNKA-NNGnLVAIGDT 118 Lactococcus lactis su...
Q9CIN8  40 VNIGIMTGTKEDDAIwsTVSKTAKDKYgITLKFTHFTDYTQPNTALKNGDIDLNAFQHYAFLNAWNKA-NDGdLKAIGNT 118 Lactococcus lactis su...
Q9CIN5  41 VKIGLMPGGKQEDAIwkQVQKIAKDQFgITLKFVNFTDGDQPNKALANHEVDLNAFQHYAYLKSWNKA-NNGnIVSIGDT 119 Lactococcus lactis su...
Q9CIN6  40 VKVGIMSGDKQDQEVwkSVAKTAKEKYdLKLKFVYFSDYNQPNEALLSGDIDVNAFQSYNYVKTWNKA-HKSdIVAVGNT 118 Lactococcus lactis su...
Q2G0V0  26 VTIGVASNDTKAW-E--KVKELAKKDD-IDVEIKHFSDYNLPNKALNDGDIDMNAFQHFAFLDQYKKAhKGTkISALSTT 101 Staphylococcus aureus...
P54594  29 IKIGIAESDGAIWNY---IAQKAEEAG-LDIQLIPFSDYAESDIALANKEIDANAFQTISYFQSFTEK-YKLnLAPLGTT 103 Bacillus subtilis sub...
Q8DRG1  36 IKIATVNRSGSEEKRwdKIQELVKKDG-ITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE-NGKdLVAIGDT 113 Streptococcus pneumon...
Q7DD63  45 IVFGTTVGDFGDMVKe-QIQAELEKKG-YTVKLVEFTDYVRPNLALAEGELDINVFQHKPYLDDFKKE-HNLdITEVFQV 121 Neisseria meningitidi...
4YAH_X 110 FVYPIAGYS------KKIKSLDELQDGSQVAVPNDPTNLGRSLLLLQKVGLIKLKd-gVGLLPTVLDVVENPKNLKIVEL 182 Escherichia coli K-12
Q9I1C9 101 IINNVGLYS------KRYASLAELPEGASVAIANDPINGGRGLQLLQKAGLLKLRd-gVGYKATLDDIVDNPKDIRITEL 173 Pseudomonas aeruginosa
Q9CIN7 119 VISPISVYS------KQLKNISDIKEGGTIAVPNDASNESRALYVLKSAGLIKLDvs-gQTLATVKDITSNPKNLVIKEL 191 Lactococcus lactis su...
Q9CIN8 119 TISPIRLYS------KKITSLSQIKSGDTIAVPNDASNESRALYVLKNAGLIGLSvs-gDTLATVKDINSNPKNLVIKEL 191 Lactococcus lactis su...
Q9CIN5 120 IITPIHLYS------TKYKNVTEIPDKSTIAIPNDVTNESRALYVLKNAGLIKLDt-sRGALATVKDIRDNPKGLIIKEI 192 Lactococcus lactis su...
Q9CIN6 119 YITPMHIYS------KEVSKLSDLKEGSTVAIPNDASNESRALFVLQSAGLIKLTtsdSSKLVGLPDITENPHQLKFKEV 192 Lactococcus lactis su...
Q2G0V0 102 VLAPLGIYS------DKIKDVKKVKDGAKVVIPNDVSNQARALKLLEAAGLIKLKk-dFGLAGTVKDITSNPKHLKITAV 174 Staphylococcus aureus...
P54594 104 YITPMGIYS------KRYERIRDISRGAVVSVPDKAFDFGRALTVLQEAGLLTLKn-gFNGTGSVDMIKDNPRHLKLK-- 174 Bacillus subtilis sub...
Q8DRG1 114 YISPIRLYSglngsaNKYTKVEDIPANGEIAVPNDATNESRALYLLQSAGLIKLDv-sGTALATVANIKENPKNLKITEL 192 Streptococcus pneumon...
Q7DD63 122 PTAPLGLYP------GKLKSLEEVKDGSTVSAPNDPSNFARVLVMLDELGWIKLKdgiNPLTASKADIAENLKNIKIVEL 195 Neisseria meningitidi...
4YAH_X 183 EAPQLPRSLDdaqIALAVINTTYA-SQIGLTPAKDGIFVE-DK-E---SPYVNLIVTRE---DNKDAENVKKFVQAYQ-S 252 Escherichia coli K-12
Q9I1C9 174 EAVQLARALDd--FDLAQGYPHYLrLAGTIDPTRALLFDGiDN-----REYVIQFVTRGd--YQDRDGRLARFVDIYQhS 244 Pseudomonas aeruginosa
Q9CIN7 192 DASQTARALDs--VDAAVINNNYA-VTAGLKKSDAIFTEPvNKdS---QQWINIIVANK---KDENNTVYKDVVKAYE-T 261 Lactococcus lactis su...
Q9CIN8 192 DAAQTPRALDs--ITAAVINDDFA-TTAKLTVEESIYTEPvNKdS---EQWINIIVANK---KDANNKIYKEVVKAYQ-T 261 Lactococcus lactis su...
Q9CIN5 193 DASQTPRALDs--VAAAVINYNFA-ISAKISEKESIYQEPlNEdS---AQWINFIAANQ---SDKNNKVYKEVVKAYE-Q 262 Lactococcus lactis su...
Q9CIN6 193 DASQTPRALDs--VALSVVNYNYA-TAASLPNSESVYMEPlNKtS---AQYINFIAATS---KEKNNKVYKEVAKAYA-S 262 Lactococcus lactis su...
Q2G0V0 175 DAQQTARALSd--VDIAVINNGVA-TKAGKDPKNDPIFLEkSN-SdavKPYINIVAVND---KDLDNKTYAKIVELYH-S 246 Staphylococcus aureus...
P54594 175 -AVRQQDAVSg--ADVFVMKPSEA-KKAGLNPKKHTLKSGgLM-S---EEEMNLIVVRA---EDQDREALQTILELYQ-A 242 Bacillus subtilis sub...
Q8DRG1 193 DASQTARSLSs--VDAAVVNNTFV-TEAKLDYKKALFKEQaDEnS---KQWYNIIVAKKdweTSPKADAIKKVIAAYH-T 265 Streptococcus pneumon...
Q7DD63 196 EAAQLPRSRAd--VDFAVVNGNYA-ISSGMKLTEALFQEP----S---FAYVNWSAVKT---ADKDSQWLKDVTEAYN-S 261 Neisseria meningitidi...
4YAH_X 253 DEVYEAANKVF-NGGAVKGW 271 Escherichia coli K-12
Q9I1C9 245 PVVRAALDKAh-GTLYQPGW 263 Pseudomonas aeruginosa
Q9CIN7 262 EATKKTIAKAypDKSTIPAW 281 Lactococcus lactis subsp. lactis
Q9CIN8 262 EATKKAIEKAypDKRKIAAW 281 Lactococcus lactis subsp. lactis
Q9CIN5 263 KNIADSIKKEYpDGGELPAW 282 Lactococcus lactis subsp. lactis
Q9CIN6 263 KATEKAIKEQYpDGGELPAW 282 Lactococcus lactis subsp. lactis
Q2G0V0 247 KEAQKALQEDV-KDGEKPVn 265 Staphylococcus aureus subsp. aureus NCTC 8325
P54594 243 DDTAAFIEKEY-QGDLVPAF 261 Bacillus subtilis subsp. subtilis str. 168
Q8DRG1 266 DDVKKVIEESS-DGLDQPVW 284 Streptococcus pneumoniae R6
Q7DD63 262 DAFKAYAHKRF-EGYKSPAa 280 Neisseria meningitidis serogroup B
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