2N83,4UZ0,6XKJ,5GPQ,6XKK,6N1H,6MKS,2L9M,5FNA,1DGN,4I16,6BZE,5WVE,4M9Z,1Z6T


Conserved Protein Domain Family
CARD

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pfam00619: CARD 
Caspase recruitment domain
Motif contained in proteins involved in apoptotic signaling. Predicted to possess a DEATH (pfam00531) domain-like fold.
Statistics
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PSSM-Id: 459874
Aligned: 47 rows
Threshold Bit Score: 48.7098
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2N83_B   4 QQWIQSKREDIVNQMTeaCLNQSLDALLSRDLIMKEDYELVST--KPTRTSKVRQ--LLDTTDIQGEEFAKVIVQKLKDn 79   human
Q99KF0  20 WDMLESHRCRIVQSIC---PSRLTPYLRQAKVLGQLDEEEILHs-SRFTNSAMRVghLLDLLKARGKNGAIAFLESLKF- 94   house mouse
Q66677  26 RLCLEELRVLLVSHLK---SHKHLDHLRAKKILSREDAEEVSS--RATSRSRAGL--LVDMCQ-DHPRGFQCLKESCKNe 97   Equid herpesvirus ty...
6BZE_F   9 KDALENLRVYLCEKII---AERHFDHLRAKKILSREDTEEISC--RTSSRKRAGK--LLDYLQ-ENPKGLDTLVESIRRe 80   human
Q8C3Q9   6 RQLLRRCRVRLVSELQ---VAELWDALLSRELFTRDMIEDIQQagSGSRRDQARQ--LVTDLETRGRQALPLFISCLEDt 80   house mouse
5WVE_T   6 RRLLRRCRLRLVEELQ---VDQLWDVLLSRELFRPHMIEDIQRagSGSRRDQARQ--LIIDLETRGSQALPLFISCLEDt 80   human
O88843   6 KQVLRSLRLELGAEVLveGL--VLQYLYQEGILTENHIQEIKA--QTTGLRKTML--LLDILPSRGPKAFDTFLDSLQE- 78   house mouse
P55215  37 QETLKKNRVVLAKQLL---LSELLEHLLEKDIITLEMRELIQA--KGGSFSQNVE--LLNLLPKRGPQAFDAFCEALREt 109  Norway rat
4M9Z_C   7 CRALSTAHTRLIHDFE---PRDALTYLEGKNIFTEDHSELISK--XSTRLERIAN--FLRIYRRQASELGPLIDFFNYN- 78   Caenorhabditis elegans
P42573   7 RSLLERNIMMFSSHLK---VDEILEVLIAKQVLNSDNGDMINS--CGTVREKRRE--IVKAVQRRGDVAFDAFYDALRSt 79   Caenorhabditis elegans
2N83_B  80 -KQMGLQPYPEI 90   human
Q99KF0  95 -HNPDVYTLVTG 105  house mouse
Q66677  98 vGQEHLVDLLER 109  Equid herpesvirus type 2 strain 86/87
6BZE_F  81 kTQNFLIQKITD 92   human
Q8C3Q9  81 -GQGTLASLLQS 91   house mouse
5WVE_T  81 -GQDMLASFLRT 91   human
O88843  79 --FPWVREKLEK 88   house mouse
P55215 110 -RQGHLEDLLLT 120  Norway rat
4M9Z_C  79 -NQSHLADFLED 89   Caenorhabditis elegans
P42573  80 -GHEGLAEVLEP 90   Caenorhabditis elegans
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