1VA6


Conserved Protein Domain Family
GshA

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COG2918: GshA 
Gamma-glutamylcysteine synthetase [Coenzyme transport and metabolism]
Statistics
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PSSM-Id: 442162
Aligned: 142 rows
Threshold Bit Score: 710.355
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1VA6_A         1 MiPDVSQALAWLEK--HPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTDFAEALLEFITPVDGDIEH 78 
WP_083831109  40 LsEPLATAIQRMQGlaRQGLFGRLRRGIEKEGLRVDGAGRIAQTPHPHALGSKLAHPYITTDYSEALLEYITPVYCRPTD 119
WP_013331444   1 MsESLSTLIERLSGpaSQGRFGRLRRGIEKEGLRVDADGRIAQTPHPAELGSKLTHPHVTTDYSEALLEYITPVYSRPED 80 
WP_015488720   1 M-ATYNDLLAQLSLptNLPLLTQLNRGIEKEGLRASNQGIISQTPHPKGLGSALTHPSITTDYSESLLEFITPVMASAHE 79 
WP_044620432   1 Ml---ENRLKWLSS--LTPEAIRFIRGIEKEGLRVTPDSRLAQTNHPAGLGSALTHPSITTDYSEALLEFITPTFSSTEE 75 
WP_064123754   1 MsEQFARIVAGLEApvRQGRTGRIRRGIEKEGLRVDPLGRISQLPHPRQLGSKLTHPYITTDYSEALLEFVTPVYSRPSD 80 
WP_084208016   1 MsEQLASAIARLKApaRQGLFGRLRRGIEKEGLRVDADGRISQTPHPRALGSKLTHPYITTDYSESLLEYITPVFSRPKD 80 
WP_086901121   1 MsEQFTRRIDGLSApaQQGLFGRIRRGIEKEGLRVDSQGRIVATPHPHALGSKLTHPYITTDYSESLLEYITPVFSRPSD 80 
WP_106418350   6 VsDQLATNVDRLMTpaRKGLLGRLRRGIEKEGLRVDGEGRIVPTPHPYALGSKLTHPHITTDYSEALLEYITPVYCRPAD 85 
WP_038277961   1 Ml---TRLLDGLKGp-LGDGLRPIRRGIEREVLRVDAEGCIAQTPHPNALGHKLTHPWITTDYAESLMELVTPVCDSAPE 76 
1VA6_A        79 MLTFMRDLHRYTARNM-GDERMWPLSMPSYIA-EGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLP 156
WP_083831109 120 ALAFLGDLLRYSYRKL-DDELIWPASMPSRLD-GNDSVTIADYGTSNVGTMKHVYRKGLDVRYGRIMQSIAGVHYNVSLP 197
WP_013331444  81 ALAFLADLHRFSYRRL-DNEFIWPASMPARLD-GNESIPIADYGRSNVGRMKHVYRKGLDVRYGRIMQAIAGVHYNVSLP 158
WP_015488720  80 AHAYLDVAHRFAYSQM-DAEVIWPSSMPCILQ-GEMSIPIAYYGSSNLGQLKHVYRHGLWHRYGRTMQCIAGIHYNFSLP 157
WP_044620432  76 NLDYLANLHRYAYLKMpADELIWPGSMPAIID-HEEDVRIAEYGSSNIGRLKHVYRHGLWHRYGRIMQAIAGLHFNFSMT 154
WP_064123754  81 ALDFLADLHRFSYRQL-GDELIWPASMPAWLD-GNASVPIADFGNSNTGRMKQVYRRGLDVRYGRIMQSIAGIHYNFSLP 158
WP_084208016  81 SLEFLADLHRFSYRNL-GDELIWPASMPPRLN-GNDSVPIADYGTSNTGTMKHVYRKGLDVRYGRIMQSIAGIHYNFSLP 158
WP_086901121  81 ALAFLGDLHRYSYRYL-GQELIWPSSMPAELD-GNDSVPIADYGSSNVGTMKRVYRNGLDMRYGRIMQSIAGIHYNFSLP 158
WP_106418350  86 ALAFLGDLLRFSYRHL-GEEWIWPASMPSRLS-GNESVPIADYGTSNVGTMKHVYRKGLDLRYGRIMQSIAGIHYNVSLP 163
WP_038277961  77 VLAFLADLHHHVLRHLpEGEWLWPASMPARLPnGGDSVQIADYGSSHSGELKRVYRKGLRHRYGSIMQSIAGIHYNFSLT 156
1VA6_A       157 MAFWQAKSGDI--SGADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAISSSFLQ-----GKP-TslPFEKT--EsGMY 226
WP_083831109 198 EDLWPRLRELEgrTGESLEGYRSSRYFDLIRNFRRHSWLLLYLFGASPALDRSFLT-----GEApS--HLEAL--GkHTL 268
WP_013331444 159 DDFWSLLKSLDgdEQASMQDFRSSRYFDLIRNFRRHSWLLLYLFGASPAVDRSFLPd----GRVpE--GLQPH--GeQTL 230
WP_015488720 158 EELWQLIAKAEg--KEANQTYISAGYLRLIRNFRRYSWLLIYLFGASPAVCSSFLA-----GRK-H--TLDTL--HqHTL 225
WP_044620432 155 DEFWQHFQQHQq-NNQPIEDFKSERYFSLIRHFRRNSWLLMILFGASPAIDESFLK-----SPS-K--RLSHL--HrRTL 223
WP_064123754 159 DAMWRELAALEgkSGIALCEYRSQGYFRLIRNFRRTSWLLMYLFGASPAFDRSFLD-----GRKvE--GFEAL--GrRTL 229
WP_084208016 159 DDFWTLLQKMEnaEGEDARDFRSRRYFELIRNFRRHSWILLYLFGASPGIDESFLD-----GGNdD--RLKRQ--AdRSL 229
WP_086901121 159 DELWTHLQEIDgqQDVSAQAFRSRAYFDLIRNFRRNSWVLMYLFGASPAVDRSFLE-----GRD-A--GLLPH--GqQTL 228
WP_106418350 164 EDIWPLLQSLEgrEAESPKGYRSARYFDLIRNFRRNSWLLLYLFGASPALDRSFLGaagldGRC-D--KLKPWqgDgETL 240
WP_038277961 157 PEFWRILQTLEgaDDQSLDDYRTARYFHLIRQFRRNSWLLLYLFGSSVAVDDTFFT-----DMT-VpdGLVPH--GrHTL 228
1VA6_A       227 YLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIE-KDG--KRLQINSNVLQIENELYAPI 303
WP_083831109 269 AGRYATSLRMSDLGYQNKVQEQLKICFNSLSNYVGTLRHAISTPWPDYQRFGVN-VDG--DWRQLNANILQIENEYYSDI 345
WP_013331444 231 VSPYATSLRMSDLGYQNKVQEQLKICFNSLSNYVNTLRHAISTPWPDYGALGVK-GDGedDWRQLNANILQIENEYYSDI 309
WP_015488720 226 YAPYATSLRMSDLGYQNNAQSELTVCHNSLARYIETLGEAISVPVAAYEAIGMQdETG--QYKQLNTNLLQIENEFYSDV 303
WP_044620432 224 VSPTATSLRMSDIGYTNSAQANLHVCFNGLPSYIQTLRSAIHTEYPAYASMGIK-KGD--DYLQMNTNILQIENEYYSDI 300
WP_064123754 230 VSEHASTLRMSDLGYHNKVQDQLKVCFDSLDEYVDTLRHAVSTPWPDYQRTGVE-VDG--QWQQLNANILQIENEYYSDI 306
WP_084208016 230 VSAYATSLRMSDLGYQNKVQAQLKICFNSLDNFVGTLRHAIVTPWKDYEKLGVKqADG--SWSQLSSNILQIENEYYSDI 307
WP_086901121 229 LSDTASTLRMSDLGYQNKVQSQLRICFNSLENYIGTLRHAIVTPWPAYEREGVE-VDG--QWRQLNANMLQIENEYYSDI 305
WP_106418350 241 YAPYATSLRMSDLGYQNKVQSQLKICFNSLSNYVGTLRHAISTEWPDYQRMGVE-EGG--EWHQLSASILQIENEYYSDI 317
WP_038277961 229 LSEQATSLRMSDMGYQNRVQSQLKVCFNRLDNYIRTLKQGIETPWPPYEKIGVK-VNG--EWEQISDHILQIENEYYCDV 305
1VA6_A       304 RPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSSELACTRVNWNRVILE 383
WP_083831109 346 RPKRVARHDETPTQALEARGVEYIEVRCLDLDPFTPLGIDETQMRFLDTFLLWCLLSESPWIPDEECDRLDDNRRLVVER 425
WP_013331444 310 RPKRVARHDETPSQALEARGVEYIEVRCLDLDPFDPLGFDATRSRFVDTFLMWCLLSESPWITDEECEHLDDNRRLVVSR 389
WP_015488720 304 RPKRIGPSGEKPLESLSRAGIQYIEVRCTDVNPFMPVGIDIPHMQFMDVFLTWCALHDSPNISDADCAQLKDNLQSTVME 383
WP_044620432 301 RPKRTVQSGEKPVCALQRRGVEYIEVRCMDLDPFNPVGISTQSISFLELFLTWCMLSDSGFISDEECELLKQNLAGIVMN 380
WP_064123754 307 RPKRVARHNQTPTQALEADGVEYIEVRCLDINPLLPLGIDETQIRFLDAFLIRCLLADDAPIGAVECARLDANRARVVTQ 386
WP_084208016 308 RPKRVTRHNETPSQALEGRGVEYIEVRCLDLNPFLPVGIDETQIRFLDTFLIWCLLTESPWIDDEECANLDDSKRRVVEA 387
WP_086901121 306 RPKRVARHDETPTQAMESRGVEYIEVRCLDLNPFTPLGIDEQQIHFIDTFLVWCLLSPSPWINDEECDRLDDNRAHVVRS 385
WP_106418350 318 RPKRVARHDETPTQALEARGVEYIEVRCLDLNPFLPLGIDEPQMRFIDTFLLWCLLSESPWIPDEECDRLDDNRRLVVER 397
WP_038277961 306 RPKRVAHRGQTQLQALHDNGVEYIEVRCLDINPNLPLGIDETQVRFLDTFLTWCLLSPGDWIGEEECLRLDDNRARVATG 385
1VA6_A       384 GRKPGLTLGIGCEtaQFPLPQVGKDLFRDLKRVAQTLDSIN-GGEAYQKVCDELVACFDNPDLTFSARILRSMIDT--GI 460
WP_083831109 426 GRDPDLMLSVGGR--QRYLRGWSHEIFDELDAVAELLDSQE-DATPHRDALAALKPRLDDPELTPSGQLYAQLVNEnmEY 502
WP_013331444 390 GRDPELRLDHHGR--KRSIADWGHEIFAELREVATLLDRLE-EGAPHAEALAELTPWLDDPSLTPSGRLLHRLETQgeEF 466
WP_015488720 384 GRRPGLMLKRDNT--EISLQAWGIELIDDMMALAEKFDQAH-SYNFHLDSLYQQRLKLVDSSRTPSAQVLAALIDTgkEF 460
WP_044620432 381 GSQLDQDYPTMTG--SFKLRRQATAILDELQQLAEVMDQIN-GDSKYRTVIAEAQEKIDHPELLPSSKIRTLL-EDgqEY 456
WP_064123754 387 GRDPGLMLEFEDG--ALSLAEAGGRLFDELRAAAGLLDLAE-RNTPHGDAVEALAPRIGDPALTPAGEIFAALSREgeDF 463
WP_084208016 388 GRDPELTLNVKGE--ERRLRELAANVMDELGEVASLLDENHkSGSEHRDALAALAPRFDDAQTTPSGRLLTSMLDNgsNF 465
WP_086901121 386 GRDASLKLSFAQG--DRPLAECLEEIFDAMAPIAELMDSAD-DDGAHQQALAGLRELIHHPEKTPAGRMHQQMRDSgsDF 462
WP_106418350 398 GRDPALHLQVGER--QIPLAERGHEIIAGMRQVASLLDTIE-GSELHLAAVESLATRLDDPESTPSARMLRELEAHggEW 474
WP_038277961 386 GRIQDGVLSIEGR--MVTLAEQATLLFDQLADVAACLDENE-EGELHQQALRSLRAGLNDPAYTASGQAAEALTATgdDL 462
1VA6_A       461 GGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMEAADTEPFAVWLEKH 517
WP_083831109 503 LDQMLGLAERQAAELRDAPMDRAREALFEQLVETSHQQQADIERADHEDFATFLVHY 559
WP_013331444 467 VDAIMAMAREQAERLRNEPIGPARSALFDQLVDTSHQQQGDIEAAESESFADFLADY 523
WP_015488720 461 SELTLDQALQHRKTLS-EPLGVTVRQQWTAMAQESLSNQRALEENDNLPFEQYLKEY 516
WP_044620432 457 HELMYNLARQHRETLMQTPLSEQQIQSMEAITAESLKRQQEIESGDDISFEQFIAEY 513
WP_064123754 464 IDWTLERAREQAAEFLGTPMDRAREALLDQLVETSLIQQRDIEADDELSFGEYLAGY 520
WP_084208016 466 VDEVLALAKGQAEQFKTEPMERARGYLLDQLVETSLQQQGDIEAGDHQDFDTFMAEY 522
WP_086901121 463 VTWSLERAREHAQWFAETPMDPARDTLLDQLVETSHQQQRETEESDDIDFSTFLQRY 519
WP_106418350 475 ADFMTDLARRQAEAWRTTPMDAARASLFDELVATSHQQQHDIEAEDQVSFAQFIADY 531
WP_038277961 463 TTVAMRLARQHASTLRGQPLSDEMVQRLEEKRAQSIADERALVEHDQGSFDDYVERY 519
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