Conserved Protein Domain Family
EACC1

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pfam19953: EACC1 
Effector Associated Constant Component 1
Effector Associated Constant Component 1 (EACC1) is a component of a membrane-associated two-gene conflict system, a class of NTP-dependent biological conflict systems. It is found either a standalone domain or fused to EAD1 or EAD2. It is comprised of a single conserved TM helix with short, N- and C-terminal extensions. Predicted to insert into the membrane and protrude beyond both the outer and inner layers of the bilayer.
Statistics
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PSSM-Id: 437785
Aligned: 120 rows
Threshold Bit Score: 47.2726
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
PSJ27691                  8 SSPGNgtGTGAgpgpgaVNdLRRWLQRHPELRAHLRQEPAPEPa-PG-TM-GAASELLTLLLAPGGATAA-LSAAIVAWL 83 
WP_073756778              8 HEGSN--RQEA------DA-LRVWLTQEQMLRGQVRIPVDSVPl-PG-AM-GQPLELVSVLLSNTIALGN-LLVAVAAWR 74  Stre...
EFL27052                 16 EADDG--DLAI------HD-LYRWLRQDTDVRAHADLNMIPSPs-CG------KLEIIDLVVSQGLGALN-LGLSYAAWR 78 
PWI14180                  8 PDQED--GQLL------ADeLHDWLVDDVELHRTAKIR-RVPRdaVG-AM-G-VSDVIEVVVSQGIAALN-LALAYASWR 74 
SCF75096                  8 DTHGD--DTAA------HD-LYYWLRQDRELRRHAQVELALPAstSG-RM-N-VGETINMFVSNGLAAVSlLVNVVVAWR 75 
BAL90824                  7 AAE----DEQA------TLgMYRWFRDDENLAGHAVEMRDDGRp-TG-TM-G-AIEFIDVVLTHGTALAN-LVIAYATWR 71 
SDM79341                  8 ESDED--VPAL------HD-FFRWLKDDQDGPEEVRLGTAAAEr-PG-AM-G-ALEVIQVVLGQSTAAAG-LVMQFVSWY 73 
PRJNA268366:DRB96_07500   8 SDTDE--AAEL------RD-LFRWLRADEDGPDEVWLSG--EPp-TG-SM-GGGLEVVNVVLTHTMAVAN-FALAYATWR 72 
PRY28298                  9 SAGAD--GPAL------AS-FCSWLQRTPEVARHGRIRA--MParDGvTM-N-AVATIGVVISSATGIAN-VLIAYGNWR 74 
WP_143232309              8 DDD----PLAL------AS-LHRWLSRTPEVTRHGDLREIAGAr-TD-TMdD-TIAVIALVVSGVSALTD-VLGACQAWH 72  Acti...
PSJ27691                 84 QSR---RGN--Q-T-VTITLP-DGAQVTVSTENVrdLNa-RDSGELARRLA 125
WP_073756778             75 QSR---PRQpsV-R-IEV----NGRSFILDT-----SNp-GELEALARALR 110 Streptomyces sp. CB03234
EFL27052                 79 AAR---PTA--P-A-VVISA--NGRSITVRGe----CDa-ETVRRFVEAME 115
PWI14180                 75 TTR---PAP--P-G-VTVTFA-EG-TITLTD------DspEALERVLAALR 110
SCF75096                 76 AAR---PSP--P-GpVVFGR--DGMTVTVHDTSE------GTLRRVAALLT 112
BAL90824                 72 QSR---DDD----T-TEVTFTcDGRSITVKD-----ASp-ETIDRIVAALS 108
SDM79341                 74 RSRgdgRGG--A-G-FTFVRAsDG--LSVTVRHA--TD--DDVRRILAVLA 114
PRJNA268366:DRB96_07500  73 RAR---RGR--A-A-LTFTRAsDGVSVTLENg----SD--EAVRALIAALS 110
PRY28298                 75 RTR---PKApaV-T-VTL----GSVTVTVEDp--------EALEKLTRALS 108
WP_143232309             73 GNR---TRP--PaTtVTI----GDVTVDLSD---------PEVVRKLRELF 105 Actinoplanes regularis
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