Conserved Protein Domain Family
App1

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COG4850: App1 
Phosphatidate phosphatase APP1 [Lipid transport and metabolism]
Statistics
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PSSM-Id: 443878
Aligned: 137 rows
Threshold Bit Score: 291.017
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_012865081   1 MAlstggaprpledsesmsettssrpHWASRWENRFDAAlASVLRR---RGWEPRIEPYTGYGlaaTdPgdagylgdGWV 77 
WP_041685337   1 MPf---------------------------------------------aPRSSVRVQPYFGHR---S-R--------ERL 23 
NP_866146     14 MSepkpesfq--------adlrswltRAASSADDVADVA-IRRIRKrwgRAGVPQIQTYTGFA---T-A--------DTI 72 
WP_013750259   1 MFfs--------------------------------------------sKSDPIQIDGYQSYG---S-S--------NHL 24 
WP_014436613   1 MPlpr------------------flhAWLHELEASLDRW-WNVFRRalgGGKPRSVIPFTGWD---N-ThhaaaggeARA 57 
WP_025310877   1 MRli---------------------hTLIYKLDSAFGrh---------rARTPGAIDPHIGYA---T-E--------TGI 38 
WP_029140323   1 MGi---------------------------------------------fTRRPVRVQPFFGYR---N-R--------ERL 23 
WP_066847259   1 MPl----------------------------------------------FRTPPVIFPFFGYR---S-T--------TRL 22 
WP_077023510   1 MNlssrstwr--------eelkqaltEVVSCADDFVDIR-WRSLRHrfgWDGIPKIQPYIGYA---D-S--------TTV 59 
WP_112379454   1 M---------------------------------------FRYISRlidDPDPVIIMPYGGYA---T-N--------DKI 29 
WP_012865081  78 RVLGRVVLAPRQagaakhgslgdptalpessaptprrlGRPRAEGPEPLRAVRGWRSFLTAQLPGAHVIVTV----DG-H 152
WP_041685337  24 RISARALASGKA----------------------------GFDASGRWQAMRTMLAQFASREVEGLSVELELkhpgGDrL 75 
NP_866146     73 HLRGRILNNPPL--------------------------DPDFHNDRWWQNLAHTWRRFASDEVPGVTIEGSF----AG-V 121
WP_013750259  25 YLIGRALEHEGV----------------------------DLKKTSFLSTLKNAYKQFDSDELRHTKLKVTL----PDnR 72 
WP_014436613  58 VFGCRVLATPLG--------------------------GGPREKDRWWDNLRNTYRRWDTQEVPHAEVTATL----GT-Q 106
WP_025310877  39 VLRGRVLAREPK--------------------------RVRTGKSGRLGNLRAMVGLFRTKEVSAVTVAC------GG-- 84 
WP_029140323  24 VLVGRTQRSRPP----------------------------EFEQAGRWRTFRVMMSQFFASEVRNVGVTLCLtrsdGEdF 75 
WP_066847259  23 RIAARALRSRPP----------------------------RWDHDSSFAKMRALVSHFASREVDGMPVQLEIrspsGVlS 74 
WP_077023510  60 RLHGRVLTNPPA--------------------------ELPGENDRWWQNLANTYQRFESDEVPDCEVEIRL----GE-I 108
WP_112379454  30 HAQARVLEDEGL---------------------------DEHSSDSISGNLFRSFKRFETDEKENVKVYVTW----EG-G 77 
WP_012865081 153 EHRTVADRGGYVDVVVS------SGL-----GEGWHEVSVRPa-----EDGP----------TVSAPVRVVGRQVRTGLV 206
WP_041685337  76 RHSATSDGEGYLDFNIRlpgewaLPA-----ETSWEVVGLHW------VNEEge-------qCEEGFVLVPGTSAKLGVI 137
NP_866146    122 TGRTVSDSEGYFELDIPrt--adNSE-----FAFWMPAQLAI------VDDDrisp---lesFAVCDVMHVSSDAKYAVV 185
WP_013750259  73 SFYTITDTEGYFKIDEKv-----dGLgvianDEGWLQMVISF------DDVQkgitv-lgenRFPIEMLIPAETASYGVI 140
WP_014436613 107 AQSVTADEEGYAWFRISp----pPEA-----DAGLARLlVADsaadrgVDPAreaavrgaavESELPVIRPGLRAPFGVV 177
WP_025310877  85 -RTTVTDEEGYFSLTVP------RDH-----AAGWHTASVAL------PDGT----------ETPCPFFVPDPDAPAILI 136
WP_029140323  76 SYTTSSDDDGYFRFEIDlegdwpYPA-----QTAWEVVRLGW------DNRDgh-------qSVTGHVLVPGADAQIGVI 137
WP_066847259  75 RHAGFTDDEGFVHFDLPldd-wpLAD-----HTEWETVCFAW------NDGKga-------rMAEAYVLAPGASADLAVI 135
WP_077023510 109 THRTVTDAEGYFFVEEPhe--ftDTS-----RGLWSKATIQI------VNHPrvss---dasLVTCRVMTPPRNAKFGVI 172
WP_112379454  78 QETLVSDNEGYIYLNKAh----gMSLnh--eRTLWIPITYKL------NKNGme------lfSITHPVMKPSQTCEFGVI 139
WP_012865081 207 SDVDDTVMVTSLPRPL----TAIWNLLVLHEDARRPVRGMADLYAEIDSLED---------------QLPVVYLSTNTWN 267
WP_041685337 138 SDIDDTIIETGITGGFrsfmRNWRRVLAQMPNERVAVPGADAFYNAIGGGVTtpkgairpgmqidaaNRPFFYVSSSPWN 217
NP_866146    186 SDVDDTILRTGATDIG----TMAKLTFFGNARTRAPLEGVASLYEWMQHNGQrfg----------spVNPIFYVSSSPWN 251
WP_013750259 141 SDIDDTILHTGVASLLk--wRVIINTFFKNVGKRTSLEGAPELYRKLHRGKSgq------------dANPMFYVSNSPWN 206
WP_014436613 178 SDLDDTVIHTGITNLL----TAARLTFLHNARTRKPLPGVAALYAALEAAge--------------ePAPFFYVSSSAWN 239
WP_025310877 137 SDIDDTVLETGAWSLF----RNLWTTFTGNVETRRIYRDAVDVYTKLRKAA----------------NIPVFFVSSSPWN 196
WP_029140323 138 SDIDDTIIETGITGGWhnvvRNWKRIFAQMPHERILVEGADSFYGAIGGGLTvsesepptgavipttHRPFFYISSSPWN 217
WP_066847259 136 SDIDDTIIETGITGGLhsvlRNWRRILAQMPAERAQVPGADRFYSALSGGAAspgrh------lpatRHPFFYISSSPWN 209
WP_077023510 173 SDVDDTILYTGVTRLL----TMAKLTFLGNSRTRLPLAGAASLYHALQGTEKpen---------sesLNPIFYVSSSPWN 239
WP_112379454 140 SDMDETVLHTGLDSILk--wKVLVNTLGKHSDKRLPLEGAQELYTLLHGGSTgy------------rENPFFYLSNSPWN 205
WP_012865081 268 GAAALRRFFAFHGLPAGPMLLTDWGPTNTGWFR-SGREHKFHSLERLARELPHVRWILVGDDGQHDPLVYNRFAQMYPDH 346
WP_041685337 218 LFAYLVAFKRERQIPLGPLALRDWGLNRETFGSsSHGSHKLAAIREILDLHTDMRFALIGDDSQGDVTAFGQIAEEYGRR 297
NP_866146    252 LYDLLEDFLELNAIPKGPLFLRDLGIDDDKFIK-QGHDRKLEQTRYLMNAFPHLPFVLVGDSGQEDARLYATAAEEFGQR 330
WP_013750259 207 LYSYLESFVRNQKFPKGPILLRDLRGPFEKTPK-PEKPHKQHEIRNILNAYPNLKFVLIGDSGEHDVDIYLEVAKEYPEQ 285
WP_014436613 240 LHDLLTDFLRLNRLPVGPLLLQDLGLDRSKFIKrPGHTHKLDKARDLVDAFPGLPFLLIGDSGQADPHLYERLVRERPGR 319
WP_025310877 197 IHGFLLAIFERTGLPRGPLFLRDFGVDRDKFITaGHGDHKGNAIDLILQANPGCPAVLAGDTGQEDARIYRAAIARYPGR 276
WP_029140323 218 LFSYLVAFQRSRELPLGALFLRNWGFNRATIGKkSHGAHKHQAIGEILAHFSHLRFAFIGDDTQGDLPAFAEAVAREPDR 297
WP_066847259 210 LFAYLTTFMRSRRLPLGPLQLRDWGFNRETLGSkGHGDHKIAAMAGLLEFYPAMRFALIGDDTQADLVAFARIALKFPDR 289
WP_077023510 240 LFDLLEDFLELNRIPLGPLLLRDLGFDTNKFLA-EGHDHKLDKARNILNQYPDLPFLLFGDSGEDDARLYATAAEEFGEQ 318
WP_112379454 206 LYDYLIAFLEKNNFPRGTLLLRDIGLENKKRTS-FLEGNKFIKIKHILESYPKMNFILIGDAEDLDPQIYSEIAKLFPNR 284
WP_012865081 347 VRAIAIRQLSPGEqvlahgAPTPTVQARAGMsagAGPAIPVVSAPDGARLRRSLRAAGVLPGGPA 411
WP_041685337 298 IAAVFIRNTGDAH------STEEM-AAIATM---RAGGVPLWMGEEFDSAADFLSAAGLSYQGET 352
NP_866146    331 IPAIFIRDIDPETms---nHDEKVDRYTKQS---AAAGVPMHLVKDSIEVSAIAEELGLLSKDIL 389
WP_013750259 286 IIAVYLRSVKHKK------KVLRVKSVLSQY-----ETTTAVLVEKSAFAEEHARSIGLIK---- 335
WP_014436613 320 IAAVLIRDVDAGQrs---rRDRDAEAHLAAA---RAAGTPAFLVHDSAEAAGHLVRLGLLPAGAL 378
WP_025310877 277 IKAVILRTPKPGV-------DPRTERDLDAL---RATGVPVFAGRDFTAFGTELQRS--LRDQPV 329
WP_029140323 298 IAAVFIRTTEKAL------SEKEL-DAKRVI---ESFGVPLWLGNSYAIGRDFLRAAGVAPHGET 352
WP_066847259 290 VAAIFIRKAGEAH------SAEEV-QARDDI---GRANVPLWMGSEYDVGQEFLDAVGLTHDHEA 344
WP_077023510 319 ITAIFIRDVDPDVis---dRDESVGASIKRA---EAAGVPMHLIRDSIEAAEILHSMQLLDAADV 377
WP_112379454 285 ILSIYIRNVRNRS------KTKNLTQYIKDTk-----HVEMLQVDNTEAILEHAKLKGFIID--- 335
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