4JDE,4JDE


Conserved Protein Domain Family
PUD1_2

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pfam18457: PUD1_2 
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Up-Regulated in long-lived daf-2
This entry includes C. elegans PUD-1 and PUD-2, two proteins up-regulated in daf-2(loss-of-function) (PUD), are homologous 17-kD proteins with similar beta-sandwich folds that further associate with each other into a V-shaped heterodimer.
Statistics
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PSSM-Id: 408250
Aligned: 25 rows
Threshold Bit Score: 157.213
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4JDE_B           4 TEQWAKVDIENKSDHVFK-FQVLHQYTGNALEASKWVKLEPNQSAQILEKVHYNTGPFTTGTDNWKVHGI---------- 72  Caenorhabditi...
PFH54930        20 VHRKANVTIMNNTDKPLVsVSVIHKYSSVYKETHEWGLISPGEVSSDHMVVQYNTGLGTIGQDWWLLSWYdeg------- 92 
PFH56069        28 THRTSPVTIINKSGTSLSsISLVHKYSNIYKERHEWAYLAPGEKAADYMTVSYHTGPLTTGRDWWLLTFYtdq------- 100
KDN70970         2 TKRTAFASVRNNTGSPIVaVSLVHKYSDDYKHQQQWGILDNGELGEEQLEVEYNTGAFTTGRDWWTVTWYspd------- 74 
OAL43060        23 TKRTALVKIQNNTPDTISgASISHKYSDVYKNQFDFVSIPAYSTSTEVMEVQYNTGAFTTGRDWWFVTYHravasaekpg 102
EJP63494         4 TKRKAFVAVVNETTSPLFaVSVIHRHGNTCKHRQEWASVPAGERAEPNMTVDFHPDCAAAAKDWWFISWY---------- 73 
KYK58405        31 TRRGAMVSVQNNSPQLLRnVTILHKYSNVYKNDQTWPEVGQDELASPLMNVEYNTGLFTTGRDWWVLVFAsed------- 103
CEJ93599        22 THRQAQVTVQNNTPNNILsISLVHKYSDNYKNEMQWPILHPGDGSWPLLTADYNTGITTTGRDWWLLTWYsed------- 94 
jgi:Alvin_2691   3 THQKASIEIVNNWGGTLLsVSVAHKYSDEYKNDHSWENIMNGESTSSTM-VDFNTGWLTTGRDWWVVTWIdd-------- 73 
EHK19500         4 TKRTASVSIRNNTSKPMVsVSLVHKYSDVYKHRKEWAAIPAGDSSDESLQVEYNTGFFTTGRDWWFISWYsqd------- 76 
4JDE_B          73 --KQIETNLDDKNGVVD--GK---VRILGE---------------------------------AWRSGHPDGADWKKHTL 112 Caenorhabditi...
PFH54930        93 ltHFHVTNPNNFRGVFDflEDqapAAMITAgitvaaaiatpagfaa-tlgasmaavvlakttsEAIFNSESTVGFKKHYL 171
PFH56069       101 grILYTTSPYNFRAAIDalESvasTLALAAagagaglagfsglgg---flaplaavalaklttDQMYNSESTAGMKQHIL 177
KDN70970        75 mrTRYYSDPENFRDIIDamESvapSLLKKAattlaglssltgpgl---iaarivakevaaatsDALFNSESTDGFKQHIL 151
OAL43060       103 slKMWYTDPSNFRSIIDflESvapSLIKAAikaaqgsnpallp-------aaraaqiaskvmcKALFNNESTAGFKQHIL 175
EJP63494        74 ---------------NNelDTlcsAIIQGLsptvagliatksefdi--pdesftlrdlarvttDVLFESSSTVEFKEHTL 136
KYK58405       104 lqTLYVTDPHNGRAIFDwlDRvypTLVGVGagaavslatletgpvs--vlagaataaavklvtDQLFNTETTDGYKQHIL 181
CEJ93599        95 lkTQYYTDPNNFRGVFDalDKvapDAIQAVigsaaalitsetgpva--aaaaaaavalakettKYMFNSEGTDGFKQHIL 172
jgi:Alvin_2691  74 kgDTYITDPMNFRGIVDflERigsDIAEPVaaisawvatgspept---skaiaaavavtsavtKRFLNSEGTNGYKQHIL 150
EHK19500        77 mkTLYYSNPQNFRGAFDavEKsvsPEALIKagtllapialftggpvlaipvtmatvavarsttDTLYASEETSGFKQHIL 156
4JDE_B         113 RVEDHAQTTVIKVL-EKEVQFVSKSGTSTTDF 143 Caenorhabditis elegans
PFH54930       172 EDVDEDEPVILIVNpDNEVRINSKSDESRTVY 203
PFH56069       178 RAEDEMGIMHVVVNpDFTVHFLSRSGLSTTGT 209
KDN70970       152 RSEDEDALTDIVINnDNTITFKSNSGNSETVV 183
OAL43060       176 RSEDEGKVTLVVIEaDNDVVFKSKSGNSETVT 207
EJP63494       137 REEDSGSLFQIVINcDNSVTFMSTSEVSKTPV 168
KYK58405       182 REEDELKLTEIVINsDYSVTFKSESGTSDTGT 213
CEJ93599       173 RSEDANAITNIIINgDGTVTFQSRSGTSSTVY 204
jgi:Alvin_2691 151 REEDKNGPTKIIIK-KGEIEFQSNSGTSTTGF 181
EHK19500       157 REEDAGKVTEIIINeDETITFKSQSGDSETVY 188
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