Conserved Protein Domain Family
F_box_assoc_1

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TIGR01640: F_box_assoc_1 
F-box protein interaction domain
This model describes a large family of plant domains, with several hundred members in Arabidopsis thaliana. Most examples are found C-terminal to an F-box (pfam00646), a 60 amino acid motif involved in ubiquitination of target proteins to mark them for degradation. Two-hybid experiments support the idea that most members are interchangeable F-box subunits of SCF E3 complexes. Some members have two copies of this domain.
Statistics
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PSSM-Id: 273726
Aligned: 23 rows
Threshold Bit Score: 152.899
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
BAB03054  94 MVPCDGLLlCIFET-GSMAVWNPCLNQVRWIFLLNP--SFRGcs---cyGIGYDGl---SRDSYKILRFVNgvftkneya 164 thale cress
BAB11501 143 MVTLRGLIlYIVC--GKACLYNPTTRQSVTLPAIKFniFVQGnehsllyFLGHDP----VLDQYKVVCTFVssss--qdl 214 thale cress
CAC33010 113 MGPCNGLI-CLAYG-DCVLLSNPALREIKRL--PPTpfANPEghc--tdIIGYGFgn-tCNDCYKVVLIes--------v 177 Antirrhinum hispanicum
BAB02248 106 VIHCNGVFlCVRE--KMLVVLNPYWGQTKRIMPRPP---FGcfd---ryALGYDK----SSGSHKILRLFGv-------- 165 thale cress
BAB02038 104 IYPCDGLIlCSTKrnTRLVVWNPCTGQTRWIKRRNR----RMcd---tfAFGYDNskssCLNNYKILRVCEk-------- 168 thale cress
CAB62106 101 IFHCDGLFvCTILkdTRIVVWNPCTGQKKWIQTGEN--LDENgq---dfVLGYYQdnksSDKSYKILSYKGy-------- 167 thale cress
BAB01456 110 VFHCDGLLlCSTKD-NRLVVWNPCSGETRWIQPRSS---YKVsd---iyALGYDN----TSSCHKILRM-Drs------e 171 thale cress
AAG12575  95 FLPCNDLLfCASWwsNKAVVWNPSLRQTRLI---KS----GEehf-rfgGIGYDSg--rPGKGYHIFGHSHsrls--vng 162 thale cress
AAD30640  97 YVDCDGLLfCTSYkfKGVLIWNPWLKQTRLF---ASnhHYPTk-----yVIGYDN-----KKRYKVLDYEFe-------- 155 thale cress
BAB02749  99 LVDCDKLLlCDME--KGVVLWNPWLRHSTWI--DQG--SNHTrme--syGIGYNN-----KGSYKIFAFCDrk------e 159 thale cress
BAB03054 165 nTgsYKPEVDIYELK--SN-SWKTFK-------VSLDWHVVLRckGLSLKGNMYWIAKWNR--KPdi-fIQSFNFSTETF 231 thale cress
BAB11501 215 eT--IISEHWVFVLE--VGgSWKRIE-------FDQPHTPTRS--GLCIGGVIYYLAFTSMfq----diVVTFDVRSEEF 277 thale cress
CAC33010 178 gPedHHINIYVYYSD--TN-SWKHIEdds--tpIKYICHFPCN--ELFFKGAFHWNANSTDifYAd--fILTFDIITEVF 248 Antirrhinum hispanicum
BAB02248 166 ----NQNNLNIYDLS--SS-SWMIPD-------GTLERDMEYMkqGVSLNGDTYWYAKDKE--SIdw-yLLCFDFTRERF 228 thale cress
BAB02038 169 -IkgQQFEYEIFEFS--SN-SWRVLD-------VNPNCIIEGR--SVSVKGNSYWFATITK--THy--fIRRFDFSSETF 231 thale cress
CAB62106 168 nY--GDQEFKIYDIK--SN-TWRNLDv-----tPIPGNYFTCSdyRVSLKGNTYWFAYDLK--DEql-gLISFDYTTERF 234 thale cress
BAB01456 172 dRipIQTEYQVYDFT--SK-SWLVDGva---ggLFIPSIGTRRr-GLSVKGNTYWLALTEDg-PPfdmfLLCFDFSTDGF 243 thale cress
AAG12575 163 nTskFIKRFYITKFE--SN-AWKCIDdvs-lgeNSIGGDSLDNn-NVSLNGNLYWTTNSYDt-DEy--lIQSFDFSKEIF 234 thale cress
AAD30640 156 ----PSSKLTIYEIGlySKk-vKDLE-------SDSSWSVVQSn-SVSLNGTLYWAGVDVN--NGi--fIRSFSFSTERL 218 thale cress
BAB02749 160 nH--TQRLLTIHDSA--SD-AWKDREpidnsqgKQIVHNIYTKisGVSLNGNLYLVTYFETt-DLvy-hLIEINSSSESV 232 thale cress
BAB03054 232 EP-LCSLPVRY----DVHnVVALSAF-KgDNLSLLHQSKETSk---IDVWVTNKVKNGVsi------lWT--KLFSVTRP 294 thale cress
BAB11501 278 N--IIQAPLVLs---AYVdSLDFIEY-G-GKPAIFYHTSLKEng-lVDLWVLENAGN-----------WSr-TVLSLQ-P 336 thale cress
CAC33010 249 KE-MAYPHCLAq---FSNsFLSLMSL-N-ECLAMVRYKEWMEdpelFDIWVMNQYGVREs--------WT--KQYVI--- 309 Antirrhinum hispanicum
BAB02248 229 GT-PLPLPFSNegytLHKgYKSLSAL-KeEKLAVLLW--DT-----MVIWVTN-KIEPDav------sWS--IFLKLDME 290 thale cress
BAB02038 232 QK--LPLPFHIf---DYNdSRALSAF-ReEQLSVLHQSFDTEk---MDIWVTN-KIDETtd-----wsWS--KFFTVRLI 294 thale cress
CAB62106 235 ERlWLPFQCDIs---DH--DYSLSVV-GeEKLSVVLQLKDAPr---REIWITN-KMDDEtke----msWR--KLFEVEVG 298 thale cress
BAB01456 244 R--RLSLPTDTp---CTYyDVSLSVTrEeQQLCMFKSHGS-------ELWIAT---KMEstg---aisWSksHRFHFR-- 303 thale cress
AAG12575 235 KI-FCVLPRKK----DSSdIPVLSVF-RgDRLSVLHKFKGTNn---MEIWVTKNKIN-Esvk---avvWM--MFMTVSIP 299 thale cress
AAD30640 219 TT-FCRLPLKY----NEDnILALAVF-RkDRFSLLKLCNKTSk---IKIWLTKNSINNReiglvedvvWI--KLMTVLIP 287 thale cress
BAB02749 233 VK-FCDLPCGTs--nFLKdAFVLRVF-EgDRFSLLKQ--CHAtk-kIEIWVSKYKINNNldr---dveWI--KFMEVSSP 300 thale cress
BAB03054 295 DLPVLLAfen-lsYPVHFIDKn--NRIVVCCEevLADkrn-vaVNIYVIGED 342 thale cress
BAB11501 337 CQLHLVDnd---iPLT-LVDTtqnGEVVLVPSdlCSPf----yILYYDIQKN 380 thale cress
CAC33010 310 -GPQVVV-------CSHVCWK---NDECLIVEd-GNGq-----LVSCAFRTN 344 Antirrhinum hispanicum
BAB02248 291 PSIYCRY-------GNFFIDEe--KKVAVVFEk-DSSs----wSWMYNPNYN 328 thale cress
BAB02038 295 NRLDYPIsmmmksPLSFFIDEk--KNIILCYDk---HrentykSLVLIVGKD 341 thale cress
CAB62106 299 TRYYMWS------GRPFLVDEe--KKIVVCCEk-CQKkcq-pvITVSMVEAD 340 thale cress
BAB01456 304 -IDEMTV-------LA---DQe--KPVFVYRFk---Pk----sNMLHIVGEH 335 thale cress
AAG12575 300 IYKDS--------KPSYFINDiyeKRLVMCCSd-ENGk-----ACVYIVKDQ 337 thale cress
AAD30640 288 DFPKLPFrwynrpDLTYFLDNddaKRLVICCYd-ETQq-----VYIYIVRRN 333 thale cress
BAB02749 301 NLPDLVDgf--dsQPSYFIED---KRLVVCSCn-ETGr-----AWIYVFGEN 341 thale cress
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