Conserved Protein Domain Family
Spiro_T2SS_lipo
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TIGR04410: Spiro_T2SS_lipo 
type II secretion system-associated lipoprotein
Members of this family occur only in spirochetes (Leptospira, Leptonema, Turneriella), as part of a type II secretion system (T2SS) cassette. Properly extended gene models always include an N-terminal signal sequence ending with a Cys residue, suggesting this small protein (about 100 amino acids) is a lipoprotein.
Links
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Statistics
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PSSM-Id: 275203
Aligned: 7 rows
Threshold Bit Score: 152.968
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
ZP_10529958    2 VRIPAF----LLALLFL---NCGSRLIKQDKLSDINAYYLDKVYALKKDTKVSPTE-------TFKKGMLVRIYIESTPS 67  Leptospira inad...
ZP_09259753    5 VRFFAF----LLALFTI---QCGARLIKKEKLFEINEHYQDKIYSLKKDTKVSMTE-------TFKKGMLVRIYVESTPS 70  Leptospira lice...
ZP_11206185    6 IRVVPF----VLLLVFS---HCSQRLIKKERLREINEYYDGKTYALQEEIKFSQTE-------VWKKGTLVKIYIESTPS 71  Leptospira meye...
ZP_09658105    1 MRFVM-----ILVVLSAflpGCRSAFVPKKQLEAFNQEYQGKKFRSREDLFFQQNDridknrlIHKKGTVVVLKVEASDD 75  Leptonema illin...
WP_000488362   2 FRIAVF----LLPSVFIflaGCGNRLIRKDAVAQINEHYSEKIYYLTKDKKVSNTE-------TFKKGMLVRIYVESTPS 70  Leptospira inte...
WP_012388657   6 IRVIPL----VLVLVFS---QCSQRLIKKERLREINEYYDGKTYALREEIKFSQTE-------VWKKGTLVKIYIESTPS 71  Leptospira biflexa
WP_014803879   2 LRWPVYnmfiLLALAFVa--ACGSKLVRKEEVQRISKDYEG-IYVVKDRIDVGNFD-------SLNKGARVKIFFKTAGD 71  Turneriella parva

ZP_10529958   68 LVKIKCFPADQKREHAIGRLLAYQVNDDFEKKSIK--IEDLDKLIDNELTEY 117 Leptospira inadai serovar Lyme str. 10
ZP_09259753   71 LIKVKCFPADQKREHAIGRLIAYQVNEDLEKKTIS--IEDLDKIVANELTEY 120 Leptospira licerasiae serovar Varillal str....
ZP_11206185   72 LLKLKVYPVAESRESSLGKLAAYIINDDIKKKQYD--LEDVEEWVSKKFTLV 121 Leptospira meyeri serovar Hardjo str. Went 5
ZP_09658105   76 WIRVRARDVTRNEEQYPGEVFLFLVEDPENEQTGEqiLAALRRILGANLAPV 127 Leptonema illini DSM 21528
WP_000488362  71 MVKIKCYPADHKREYAIGRMILYQLNDEYSGKKIT--VEDLDKLIANELVEY 120 Leptospira interrogans
WP_012388657  72 LLKLKVYPIQDTRESSVGKLADYIINDDVKKREYE--LADVEEWVNQKFSQV 121 Leptospira biflexa
WP_014803879  72 YVSVYAYPYSQPREEANGKNILQMFEGDFPDKKFS--EELLRKRIADLVEEH 121 Turneriella parva
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