Conserved Protein Domain Family
DotA_TraY

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TIGR04346: DotA_TraY 
conjugal transfer/type IV secretion protein DotA/TraY
Members of this protein family include transfer protein TraY of IncI1 plasmid R64 and DotA (defect in organelle trafficking A) of Legionella pneumophila.
Statistics
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PSSM-Id: 275142
Aligned: 20 rows
Threshold Bit Score: 452.622
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_007351463  33 FGKWIIDSLFEAGSISSQA---GS-Ag--------IVGATIMPLSLVCMMVAALIIAMKSIQHLLIVAQAKDLDQSP--V 98   Marinobacter s...
WP_011154476  69 LSRQMLHTVFGEVVNNPFS---PS-Gd-------gLLNNVFFTVNEVIAILALVYMGIISIKKLHQAGQLGSFIEGD--G 135  Erwinia amylovora
WP_007248222  37 LSRQALATIYGDVVNNPLA---SS-Etgg---vdtILASIFQVLNGALLVVGSLWACYIIFRKLTRTAHDGAVFDKQ--N 107  Pseudomonas sy...
ESA70012      19 LSRQALVTIFGDVVTNPLS---TS-Dp-------tLIGSMFWVFNNIIAVLAIVWCIFISIRHVVRSGHQGQVFS-V--G 84   Escherichia co...
WP_013397334  50 kSYEVLRMVFGQFAENPFL---EV-Gtp-----dsLLGHVFLISNLVIMGLGIVWFTYNILAGILTSAHEGRVLGQK--M 118  Achromobacter ...
WP_006035795  31 LSMTYLATIFG-VVDGVLH---GT-Gs-------qILGSMFGAFNSIILVMASTVLSYVLFVSILNTSHEGEFLGRK--W 96   Rickettsiella ...
WP_012382996  42 WAAQAINNIFPINQNGat----------------tVIGQIMGQLTRFVMAIAMAFLCYHFIMNIHRVAETSRLMTDA--M 103  Beijerinckia i...
WP_013755135  34 FSVQFFKIIFGSVANVMLGqdvGI-Eep-----dtVMGEIMYLWNSFLHLVCMLVILWNGFMWMVQA-----MMGKSssY 102  Glaciecola sp....
WP_012606239  38 LALINLRKLLGCVVDGVWT---AAsCtd-----drPLTVALGYFNVGCLIVATILACYLLYSMVADSANDGEAFGRQ--S 107  Methylobacteri...
WP_012077412  19 HSVDMLRSIFGPVIDALVT---GA-DpdtvsaasnVIATMMSFFNSGILIVGTLIVSYVAAMGTINTANDGEAMGRN--W 92   Pseudomonas ae...
WP_007351463  99 SMTWA-PLHMVIAVVLMVPLPSGYSMGQYGAIWVA-HQSNTLGNLT-----AAN--TTSFFKNTGVITAP-----AIP-- 162  Marinobacter s...
WP_011154476 136 NNAFK-IVKTTFGWLLLVPTVVGWSVAQLLFLWCGsIIGVGSANVIa----DKT--ASELASGKAVYIAP-----VMP-- 201  Erwinia amylovora
WP_007248222 108 TTVWG-PVRIVWGLVSLVPTANGWSLSQLLMLWSAsIMGIGVANLStd--aAIS--A--FEDGKGMVVQP-----AMP-- 173  Pseudomonas sy...
ESA70012      85 RDIVG-ILSFVAGFLMIVPTGNGWSLAQLIMLWGAsIMGVGSANVMvq--vAAD----NIANGYSMTVQP-----VQA-- 150  Escherichia co...
WP_013397334 119 SSAWL-PVRTTVGVAGMLPVFGGFSAAQALFMWFT-LLGIGAANMSln--aSID--AASNYAPLVQSEAM-----VNPlg 187  Achromobacter ...
WP_006035795  97 SSIWV-PLRTVGGIGLLLPKATGYSFIQVLVMWVV-VQGVGAADEVwn--vALN--YMNRNGTIVEPIQS-----LAP-- 163  Rickettsiella ...
WP_012382996 104 --TWMgVVRIGFAAIMMFPLASGFSNGQAMVVKTA-MWGIGMAKAVya--nAIQ--A--IGPDALVIAQP-----MIP-- 167  Beijerinckia i...
WP_013755135 103 DTIGI-PLRFVIAIIGSVPYGHGYSLIQLVNFVGA-SVGIQQANEYa----GVV--YDNMNAGGDITQYS-----AYL-- 167  Glaciecola sp....
WP_012606239 108 SAKYT-LLRVITGAILSLPIKSGLSLVQILVVQLA-VWGSGFGDTLwtrvaGTG--LTGMYGTLTSPTQAlgdfvLRG-- 181  Methylobacteri...
WP_012077412  93 SSLWT-PVRIVAGGAVLLPTTSGFSFIQLVVLMFA-LWGVGFANGTyk--tGMAigALSPDGVVQGVNDPg----SFY-- 162  Pseudomonas ae...
WP_007351463 163 ---S----------IKTVADGIILSEMC----RY-----Lnnea-gsyVEDNGGVPITVERRAMTIDELSAIGGASVkY- 218  Marinobacter s...
WP_011154476 202 ---E----------MASVAKGMFETNLC----AL-----G--------VNQGIAQMEASGQHYENNARMQYQTGDST-Y- 249  Erwinia amylovora
WP_007248222 174 ---S----------TLQLGHNLFEANIC----MH-----G--------INAGLAEAAVQGGLVTQGGYVQQVPTSS---- 219  Pseudomonas sy...
ESA70012     151 ---S----------TRTAARGIFEMELC----KY-----A--------VNAGLNDFNQTAKSSTSLMTESAK---TAsG- 196  Escherichia co...
WP_013397334 188 sgvL----------SADVADALFISKVCvlanRA-----Yd------dPDGYDSSNLLIDNLDSAEGARTNQIYGERl-- 244  Achromobacter ...
WP_006035795 164 ---DhnlgegdntfLINRAGNILKSEAC----ML-----SvqnaltreIAQNAGEKVYVPNFMSSLSVTGKSPGGANtGl 231  Rickettsiella ...
WP_012382996 168 ---G----------TSTTVINLIQNEFC----RA-----L--------INQASGNPNLVPIPNPVVGEPVATLTYIT-W- 215  Beijerinckia i...
WP_013755135 168 ---N----------SDELVNNLFLSHVC----MQ-----L--------INNYEEEQYIDRISESAIPSEGLSEDIIL-S- 215  Glaciecola sp....
WP_012606239 182 ---K----------LAKVLEGRLYGYVC----AQalqtyAr------nVSGRDDAAAISPKTTVDDGYFGSWSARSTsY- 237  Methylobacteri...
WP_012077412 163 ---G----------LRDFGKQYLAASYC----AR-----Aa-------nQIYPGAQVSAAPSADKTTTNG----GRTeY- 208  Pseudomonas ae...
WP_007351463 219 --------GaenglsrsgFTFARKRAGgffggy-stvddyCGAVVIQ-FAarskatfG-DDNVVPlqrqgasnlvsgaae 287  Marinobacter s...
WP_011154476 250 --------S---------ISVNNGSAV-------------CGTVSLP-QR-------P-AGWTSI--------------- 275  Erwinia amylovora
WP_007248222 220 --------G---------FVLKNKSFi-------------CGGADIN-AD-------L-EAQSSStn------------- 247  Pseudomonas sy...
ESA70012     197 --------N---------YTVTVSNGSg-----------iCGTASLS-VE-------G-NGTTDQstigk---------- 229  Escherichia co...
WP_013397334 245 ----------------------------------------CGGVNLAgFL-------G-DNARSGsglqg---------- 266  Achromobacter ...
WP_006035795 232 pidyskdiG---------GFITFPGKKglvntpyakyigiCGNASWN-FI-------G-KDDHNQvd------------- 280  Rickettsiella ...
WP_012382996 216 --------A---------YGLASGNETgt---------pvCGTVTLQ-QSsgat-------------------------- 242  Beijerinckia i...
WP_013755135 216 --------G---------YLMSFGQDSwwgty----deqeCGSYEFS-NL-------A-GDESYTn-------------- 251  Glaciecola sp....
WP_012606239 238 --------H---------FVDTNGYFRksd--------nlCGAVVYE-HQ-------K-ISATIAdtn------------ 271  Methylobacteri...
WP_012077412 209 --------L---------FQIKDRNATtnlgg----geplCGTVSIS-QY-------TaQPAKDAtg------------- 246  Pseudomonas ae...
WP_007351463 288 kcqygpLCIGGVNVAHQDAKTSAINIFSEAhngaitafeadktktaaIGIAEGILYDIPlyfESKSSS------Eaaq-- 359  Marinobacter s...
WP_011154476 276 ------FASGYADSVYSVQQQATDTLWGKM-----------------KTAAEQFNAAYM---AKMRSG------D----- 318  Erwinia amylovora
WP_007248222 248 ----wfSTTIDTSQIRKAHLDALVAMQNTI-----------------TNSALNFVNEVV---QKKNGA------G----- 292  Pseudomonas sy...
ESA70012     230 --ffnpFSKNEYSGVISAQRAAMDNMISDM-----------------DNAASEFVTTFL---EKRNSG------N----- 276  Escherichia co...
WP_013397334 267 -alsyrVDSVDYDAIAKAGRQAMVGQLRGL-----------------NALVDPIAVGWFrgyQKALAN------G----- 317  Achromobacter ...
WP_006035795 281 ----npAQLTANDSASIAARQMTL----DL-----------------GGLAKSIANKLV---PPNSTT------Pilp-- 324  Rickettsiella ...
WP_012382996 243 ---nlaGVSVDMPAIQQQILQSVLNA--DI-----------------RSTVPMVVQNFW---QTKQAS------Alapll 291  Beijerinckia i...
WP_013755135 252 -----gIAEEGLTSSLFTAATTLDNNIGDL-----------------VT---EFIPNIW---GGAKIEseeaeyE----- 298  Glaciecola sp....
WP_012606239 272 ---dasTTRTLIDLAERQSQQSLQAAIDSL-----------------DGAAAGIARTIN---SGSRDD------G----- 317  Methylobacteri...
WP_012077412 247 -------iEAALEQLRVAAQNSKIQAATKL-----------------MTDLEAWVNTWP-----DDIS------G----- 286  Pseudomonas ae...
WP_007351463 360 -eytQSLKEE--PARIDTAVKASVALIGDLQSDVYSSYTKAIN-------KFgttrtgnsgsnflDIVDQVGWPVLGLYW 429  Marinobacter s...
WP_011154476 319 ----GELPDV--ESAIQTAARDYQLQVQHAANSAAGDDEIVQK-------ME-------------SDIKEKGWLYLGVYY 372  Erwinia amylovora
WP_007248222 293 -----DISDV--EGVIQSAAQTYEITVNQSVGTKQGDIEALAN-------QMs------------TSIKEAGWWSLGAWY 346  Pseudomonas sy...
ESA70012     277 ----GTLPDI--ETRIQKAADEYERAVQKSLPTDNGEQSR----------KEal----------kSYLTTYGWVTLGAWY 330  Escherichia co...
WP_013397334 318 ----TPMPEW--PTEHLTKARKGVRLVYDIVKPLIPKQSAIRK-------EAs------------DKIKRDGWAVLGAWN 372  Achromobacter ...
WP_006035795 325 -iqlTVDPSLfsPNSLVDAGDDYFAIVKPALRSLNDDASQQYK-------Kf------------iTKAKEAGWILAGSYY 384  Rickettsiella ...
WP_012382996 292 qifqTATADY--TQQLTNTATQVTSQLRNALSDPTQARAGSIG-------LItn----------eTQLNSLGWTSAGAYY 352  Beijerinckia i...
WP_013755135 299 ----TLMEEM--NDSLETIRGTYKADVNAALLQYEDDRQTYIDdnqeavpSFts----------nFDAREVGWMALGATY 362  Glaciecola sp....
WP_012606239 318 --------AI--KRQIKQAIDAAYTSVSQSLTQSSNEQLNQAL-------Rny-----------lANATDNGWLAAALWQ 369  Methylobacteri...
WP_012077412 287 ----DWSNVD--SAKFNELVNSAETQVAAALMAALSDTTGVKS-------GFqs---------laTSLTSEGWAMSGGWY 344  Pseudomonas ae...
WP_007351463 430 FQYTNFSQQVMDSAS------VQATYTGDldkfmtsfeqvlD---DP----VLTSRIKGRI--RAYRAALANElqn-trY 493  Marinobacter s...
WP_011154476 373 HTLATANTEMKDVAN------LKPVVSGM------------SndgDI----GSIDYFKGLF--QAYHSQLKNS------N 422  Erwinia amylovora
WP_007248222 347 QTFAQANTKLTDAVA------AKAGSYGP------------SsggDP----AVVNLYQGAM--DAYAVQKSTN------T 396  Pseudomonas sy...
ESA70012     331 QTFATANQRLAELAD------RAPAVTSM------------SslgEV----GDTDLFSAVM--SAYKTQLqn------tT 380  Escherichia co...
WP_013397334 373 STIAEANAAIVDAAN------VYSVTVVA------------P---GSrvgfGLGEIGDQIR--GIGQRVLSSVgla-dvP 428  Achromobacter ...
WP_006035795 385 YNMARLEQSIKENTG------LLAIKDKLntsffpnydkgsF---ND----ISNENVKINL--KNNLPMNNGVidryvdA 449  Rickettsiella ...
WP_012382996 353 LEIARLNGQTMSLLN------ATPMVSPP------------S---FE----GLSKSLKNDL--APLVTAETQFlsnlrsY 405  Beijerinckia i...
WP_013755135 363 MLQSIQTQAGLQFV---------------------------K---GN----TLKTRSDILP--DVYEIEDIQAal--ssA 404  Glaciecola sp....
WP_012606239 370 RSMSLVQAKLLAASA------GPSGAIRV------------E---PP----ANITAYIPYFghSAYAPLAEEAqr--nlT 422  Methylobacteri...
WP_012077412 345 QRVGEVRGRIAAITSesvgsvSAPSLSAL------------P---AD----AAASRLIGSV--TTVTEAISKKseakgnY 403  Pseudomonas ae...
WP_007351463 494 D-ANPAATKGLSLE-----DKTLQTS--KDmlaiR-EAFPLMQETMLENSyrgsmnPQ------NVMDSVTQN----I-- 552  Marinobacter s...
WP_011154476 423 Y-TPPLGTESNALArnidqKSLENAA--TT----G-DGTSLITKIFDFNV------TN------WLATSNYGT----G-- 476  Erwinia amylovora
WP_007248222 397 N-ANSLGASGSQGT-----ETSKVMS--HL--------FAPMQKI-----------TT------SLVTDVNFN----G-- 437  Pseudomonas sy...
ESA70012     381 Y-TPPLGTVTSANE-----QRMANAQ--DP----K-SALSEMMSFFVYR-------TN------WIATEISGT----G-- 428  Escherichia co...
WP_013397334 429 Q-TDQVRDALAALS-----TKRETAA--PA----S-ECFFDSWQTETGNC------SMgqalalRMIDGIAAN----S-- 483  Achromobacter ...
WP_006035795 450 E-MALAGSNNNPGP-----EANPTFP--EN----K-GEIPAVGKLVNGLM------NI------IFPQVYDFE----Ktl 500  Rickettsiella ...
WP_012382996 406 V-TTTDGLDAPTGN-----AQLFSGA--TP----GgDGASAIEQVMRSIH------LSdrv-lsYFTEAMSPT----G-- 460  Beijerinckia i...
WP_013755135 405 --AQVVGVNMPSGE-----KAVSQLK--EL----Q-NNSSALIASA----------AL------WFV------------- 441  Glaciecola sp....
WP_012606239 423 YvATFGGYIAAQGS-----ASVASVAsdHP----T-AQMDPPNQFARGL-------SM------IYASVLDRI----S-- 473  Methylobacteri...
WP_012077412 404 K-APTSGPGDLT-------SVIPKDA--QS----D-INIGSINADFDAKV------SL------WINSMMESMvemaT-- 454  Pseudomonas ae...
WP_007351463 553 --NtITRSILFPAIiaplrednlvnALVNTGHNIIVISEiiyasnvliRTYKQRKLADKKEPETENKSWIGKAWS---FM 627  Marinobacter s...
WP_011154476 477 --D-GYSDVTNPLL-----------KMKAIGDYTLGVAEvg------lASWTAINVAVKVSEGKSLPGFAAGMMN---KL 533  Erwinia amylovora
WP_007248222 438 ----EQGSQLNPLI-----------KMKNLGDALMGTAEva------vATYGGLKALERVTDGNNAVGLTTKFVN---FF 493  Pseudomonas sy...
ESA70012     429 --T--TSDQVNPLI-----------KMKNIGDYTLGTTEil------wSGYTTVRVLATVGDNSIFGKVANLFSG---LP 484  Escherichia co...
WP_013397334 484 --G-GN-GLVNPII-----------ASKNVGDWLMMLPQ---------VAYVASKAKDLPGPGKAVSAAAAAASK---AN 536  Achromobacter ...
WP_006035795 501 sdN-INKQHKDPIF-----------ALVSVGNGLVAMVE---------KVW-----IGILGAAVALGGISGVVSF---FF 551  Rickettsiella ...
WP_012382996 461 --N----NWTDPFG-----------SLMQLGHKLIVIAL---------TALGAAGLLSSTTGTVASTAWNILTLN---FA 511  Beijerinckia i...
WP_013755135 442 ------SNGDDPIM-----------SAMNYGHNLIAIGEl--------SILLSKPLEALSKTLSAEVNEETTDLP---VV 493  Glaciecola sp....
WP_012606239 474 --RpESSAWKDPIL-----------EIQEIGQVI--------------AYWGMGATGGAVGSDILDWGLGKLRLS---DD 523  Methylobacteri...
WP_012077412 455 --G-ANSSGTTPLCgtagqmggslnRMKCIGDYLTV------------ARAGIGAADVAIKTGATALRVVAGTLSsvkGV 519  Pseudomonas ae...
WP_007351463 628 SnpisS-SAAWVMD-AL-FIGFA-------IdallivlndfAQLWFYVFLMGLFLAFYIPAMIMIQWLIGLVTWIIYIVE 697  Marinobacter s...
WP_011154476 534 T----G-IRDAIAG-VLeSVSFL-------V----------YPLFYSLFGIGLALSIWLPFIPMIYWFVAMADWLVTLMT 590  Erwinia amylovora
WP_007248222 494 S----G-GLDAGKG-LLdAMSPF-------I----------IMAIFALFLLGATLSIYLPMTPFIIWFGAAINWLVVVGE 550  Pseudomonas sy...
ESA70012     485 K----G-----LVA-LLdAAAPP-------I----------YFLLFLLFCAGFSLSIYLPFIPFIFWMTGIGNWIVSVLI 537  Escherichia co...
WP_013397334 537 G----GfGPTALKM-FGsDTLKI-------L----------EKLAIAMFIVGAILAIYIPFVPFLTWMTGLVGYFCIVVE 594  Achromobacter ...
WP_006035795 552 PgpaiV-AGLVASV-IIsVFMPL-------I----------TIWMIINLILGSLLSYYVPLIPFFLFTFGAITWFAVVLE 612  Rickettsiella ...
WP_012382996 512 G----A-AASVAGSaLVqFFGTP-------I----------FLACLALLIPGLTIAFVLPMIPWVMWMAGVAGYLILVCE 569  Beijerinckia i...
WP_013755135 494 GeianI-RRFTLAA-LEtIISTGmt----sL----------LTMAYALIIAGVYFAFYLPALPLIHWIGAALGAVIANVM 557  Glaciecola sp....
WP_012606239 524 G--------ALRSG-LReMTGF--------L----------YCLAIVLFVAAFLLIGLVPFIVIVHFLMATFNWFLVVAE 576  Methylobacteri...
WP_012077412 520 G----T-GLDLDKV-VTpIWDWVievpvkqL----------AMMATYIEPMAFYFGVFLPSLPYVIFMTVVVGWILAVLQ 583  Pseudomonas ae...
WP_007351463 698 ATVIIPLWGLLFTADm-GQkSFaPQTAQQGFIHILSILVYPSLMTIGFVIGLKVIDLASIFLVEYLlvGLMNSSEGYV-- 774  Marinobacter s...
WP_011154476 591 GVLASSLWAATHINI--GQ-SN-DERSTYGYVFLIDVMIRPMLMVMGFIFASLAIVALGTALNMMFkfAMEQVQSDSF-- 664  Erwinia amylovora
WP_007248222 551 AIIAAPLWAFTHLGGe-GD-GM-GQRTAHGYLFLLNCMFRPTLMVVGFFLGGAIVVAGGTLLNNLFgiAIANVQYDSM-- 625  Pseudomonas sy...
ESA70012     538 GCTAGPLWAATHLGTs-ED-R--GSRAAYGYIYLIDSMIRPPIMVFGFFFASVAIIAVGTILNALFgaALVNVQFNSL-- 611  Escherichia co...
WP_013397334 595 GLVAGQLMAFAHLSGe-GD-GM-GARTERGYTHLPNVLLRPTLMVVSFYIANAMSIMIATLFLQLFaaALANVQGNSV-- 669  Achromobacter ...
WP_006035795 613 AVLAAPLVALGITHPe-GH-DFlG-KAEQSIMLLASVFLRPMLMVFGLIFGIILSYVALSVFNRGFaiAVQFLTEYNG-- 687  Rickettsiella ...
WP_012382996 570 AVVAVPLWMLAHMTLe-GA-GLhG-RAIEGYGLLFNLLFRPVLMLFGLFLGYTIFAAMSWLVRMSFgiAAGFVLANGWvv 646  Beijerinckia i...
WP_013755135 558 NIILAPIHIIAHALId-GH-GIiGQNARQGYLIMFGAYLRFPLTVIGFVALYPLLLGAGKLVILLYtpYVSSMVSGHV-- 633  Glaciecola sp....
WP_012606239 577 AMIAVPIWLLTKFMParSD-SFvG-NSGQGYLFFLGILLRPPLIVIGMLVSILLMRVGIDISNIFFrgALAMIAPDGT-- 652  Methylobacteri...
WP_012077412 584 SLIAAPLWAVMHMTPd--R-TFvGSQS-QGYLLLLSLFARPALAVVGLFAAMLVSDPIIDFIAKGFfaMRGAVVTSTG-- 657  Pseudomonas ae...
WP_007351463 775 Y--GILSMIAG---LLILGLACYQVITRVFSLVLELNDRAMSWIG 814  Marinobacter sp. ELB17
WP_011154476 665 T--GLLSSIGF---LMLYARLCTGMVARVFALPARMPNYVINWIG 704  Erwinia amylovora
WP_007248222 626 T--GIFSALFF---VAVYCSMCLNLIHSSFNLIFIVPDQVINWVG 665  Pseudomonas syringae group genomosp. 3
ESA70012     612 T--GIFSLAGF---LLIYARICTTTVAAIFALQAYLPDHVINFLG 651  Escherichia coli 113303
WP_013397334 670 T--GIASIIGL---VVLFMIGMMVMIQGIYNMVYEIPDRSLGWIG 709  Achromobacter xylosoxidans
WP_006035795 688 DllSIIYQLAM---MAIYTAAILAIVNRSFAMIYEVPNKVLRWIG 729  Rickettsiella grylli
WP_012382996 647 T--NILGVCVL---LSIYVTIHIVLALTSFRLITLIPHHLPRLVG 686  Beijerinckia indica
WP_013755135 634 T--GGVTFIAI---TVLLGTLLSAVIERCNNVMHELSDSAMRMIG 673  Glaciecola sp. 4H-3-7+YE-5
WP_012606239 653 IayAMVGT-AG---LFVYAVILFSIVALAAGQISALPETVLSWIG 693  Methylobacterium extorquens
WP_012077412 658 TvgAIASFLSFawwFMVFGLTLLPVLYMIFGLPQILPDHVLRWIG 702  Pseudomonas aeruginosa
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