1I8J


Conserved Protein Domain Family
ALAD

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pfam00490: ALAD 
Delta-aminolevulinic acid dehydratase
Statistics
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PSSM-Id: 459829
Aligned: 592 rows
Threshold Bit Score: 345.082
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1I8J_B         5 QRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDYKAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFGIS--H 82  Escherichia coli
XP_001609639 159 TRLSRTRVSKNRHKLFRGRVLHLADLVYPLVVTD-KESSSSIKEVPGLRLLSIPDLVKEVEEARNLGITAFMIH--PhiD 235
Q8IL68        98 RRERRIKRNKYLLSLYNNTNIKTSNFIYPLFIHE-EDVEKKHTQLEGIYTYNVDGIIKEIEECIKLNIHHFMFF--PviR 174 Plasmodium falc...
XP_003171517  31 SQLKSGYNHTVSAIWQAERQLHKSMFIYPIFLSADPEMEEPISGIPNQYIRGLNKLLPFLSTLVAKGLHAVILFGTl-lS 109
EFR02786      29 sqLKSGYNHAVSAMWQSEKLLHKSMFIYPVFLSADPEMEEPITSLPNQHRRGINKLIPFLETLVAKGLHSILLFGSp-pS 107
XP_002618428  95 ailqgGYNHPLAREWQSERRLDKSMFIFPLFVSDIDDEETAIPSLPNIKRYGVSKLADYVGPLVEKGLAAVILFGVi-lK 173
CCH61216      16 silaggYNHPLLREWQSERQLHKNMFIYPLFVSDIDDEVTAIESLPNINRYGLNTLKPYVESLIKKGLRSVILFGVp-lA 94 
Q6C0Y3        17 silsggYAHPLSRQWQQKNRLTKDMFIYPLFVTDDPEEETPISSLPGQKRWGVNKLVPYVDSLVKKGLRSVILFGVp-mK 95  Yarrowia lipoly...
WP_012388166   3 KQTLRLRSHKSLRHLSESGSLNVNKMIQPLFLVEGLTEKEPIKGLPDVYRDTNQTIFKQIESDLKSGVSQFLLFMVP--- 79  Leptospira biflexa
Q8EY45         3 TKQRRIRLNAGLRNLASSESLNSKKLIQPIFIVEGLKEKEKMDSLPGVFRDTESSVFKQVESDLKAGVTHFILFFIP--- 79  Leptospira inte...
1I8J_B        83 H--TDETGSDAWREDGLVARMSRICKQTVPE-MIVMSDTCFCEYTSHGHCGVLce--hgVDNDATLENLGKQAVVAAAAG 157 Escherichia coli
XP_001609639 236 KslKSEFGDEGLNPDGLLPRAIDAVKEAFPD-VQVFADATVAHFSLDGHDGLVepetdvISNDVSVSQLAKQVTTLASAG 314
Q8IL68       175 EenKTVYCEESYNENSYFCKTISRIKEKFSDdIIVYTDVALDPYNIYGHDGIYddnkkeILNDITVHTLVKQSLCLAKSG 254 Plasmodium falc...
XP_003171517 110 ThiKDNVGSMADSESGPIRPAIPIIRQAFPD-LYVIADVSLCEYTDHGHSSVLled-gsVDNEATVTRVSDMALSFARAG 187
EFR02786     108 TdlKDGSGSLADDIRGPILPAIPLIREAFPD-LYIVADVSLCEYTDHGHCAVLfkd-gtVDNEASVARISDIALSFAQAG 185
XP_002618428 174 DgvKDAQGTAADDPDGPVIRAVRLLREKFPS-LYIMCDVCLCEYTSHGHCGILcdd-gsINRAPSVSRIAAVALAYARAG 251
CCH61216      95 PgiKDPIGTAADDPNGPVIRAIRMLRESFPS-LYVMTDVCLCEYTSHGHCGILfpd-gtIDRKRSVQRIAAVATNYARAG 172
Q6C0Y3        96 EgvKDLEGTAADDPEGPVIQATKALKKAFPD-LFVMCDVCLCEYTSHGHCGVLred-gtVIRDTTVRRLAAVAVNYAKAG 173 Yarrowia lipoly...
WP_012388166  80 ---NEKSDTSF--SKEFYHSNISAIKKTFPE-MFLWLDTCICSVTTSGHCCHFhpk-gnIDLKLTLNRLSELALIYADAG 152 Leptospira biflexa
Q8EY45        80 ---ELKSNSEI--PKSFYERSISSLKKKFPE-SFLWIDTCMCSLTTHGHCGLLhpd-gsIDNHTSVKHLSDIALVYAQSG 152 Leptospira inte...
1I8J_B       158 ADFIAPSAAMDGQVQAIRQALDAAGF-KDTAIMSYSTKFASSFYGPFREAAGSALK-G-----DRKSYQMNPMNRREAIR 230 Escherichia coli
XP_001609639 315 CDVVSLNDTLDGSVGVARDALDFEGY-TDVSLMSRAGKFNSVYMAQHQAMLGTTPAqn----vRVESYLHDVAIPDEPIL 389
Q8IL68       255 ADVVCPSDSMDKRIELIRKNLDFHNF-RDILILSYTCKYSSSMYKPFRSILNSNi--LknfvkNKQSYQHDFNSYMD-LN 330 Plasmodium falc...
XP_003171517 188 AHCVAPSDMSDGRIRAIKLKLLEARLeGKVAIMSYSAKYASCLYGPFREAIKSNLVtD-----EHKRYLLPPPARKLAHR 262
EFR02786     186 VHCVAPSDMSDGRIRAIKLKLISARLeSKVAVMSYAAKYASCLYGPFREAAASTPRfG-----DRKRYLLPPPARGLARK 260
XP_002618428 252 AHCVAPSDMMDGRIGAIKRGLIDEGLdNRVLVMSYSAKFSGNLYGPFRDIAGSAPShG-----DRRSYQLPAGGAGLARR 326
CCH61216     173 AHSVAPSDMIDGRIFAIKQALLKENLaHKTFIMSYSAKFSADLYGPFRDAACSSPSsG-----DRKCYQLPSSAKGLAHR 247
Q6C0Y3       174 ADCVAPSDMIDGRIHDIKKGLLKAGLaHNVMVMSYT-KFSGNLYGPFREAACSAPShG-----DRKRYQLPAGGRGLARR 247 Yarrowia lipoly...
WP_012388166 153 ADGIAPSDMMDGRVASHRKILDENNH-SHVPIMSYSTKFKSHFYGPFRGAADSSPQfG-----DRSGYQLDVRDRETAIQ 226 Leptospira biflexa
Q8EY45       153 ADGIAPSDMMDGRIKSHRSILDVNGF-SNIPILSYSTKFKSNFYGPFRAAADSAPAqG-----DRSSYQIDVRNREDAVL 226 Leptospira inte...
1I8J_B       231 ESLLDEAQGADCLMVKPAGAYLDIVRELRERT-E---LPIGAYQVSGEYAMIKFAALAGAID---EEKVVLESLGSIKRA 303 Escherichia coli
XP_001609639 390 KGVQDVDDGADMVAVEPATAFVDVIRSLKDRL-R---SPVVAVHTTGEYRALKAAAAAGVYD---EKAAAIEALRGLRRA 462
Q8IL68       331 NVDKHIIEGADIIMVKPSMFYLDIIHKIKNRIkDdvqIPIAVYNVSGEYMMIKNYVKYLNEDinyENEIITELFKSYLRA 410 Plasmodium falc...
XP_003171517 263 VMLRDMHEGADMIIVKPA--YADIISDAKGIA-N---VPVAAMQVSGEYAMLHAAASAGVFD---LKTIAFETTEVIVRA 333
EFR02786     261 AMTRDLREGADMIMVKPA--YPDIISDGKELS-E---VPVVAMQVSGEFAMVHAAAAAGVFD---LKEMAFETSEIIVRA 331
XP_002618428 327 ALVRDIAEGADAFIVKPSTFYLDVVSEASRICrD---YPLCVYQVSGEYALLHAGAAQGVVD---LKAIAFEAHNGYLRA 400
CCH61216     248 AIERDLTEGADGIIVKPSTFYLDIISDASTQCkD---VPLCAYHVSGEYAMLHAAAEKGVVQ---LKQIAFESHMGLLRA 321
Q6C0Y3       248 ALARDLAEGADAVIVKPSTFYLDIVVDAAEICkD---VPIATYQVSGEYAMIHAAAEKGVVD---LEVMAFEAAYGNLRA 321 Yarrowia lipoly...
WP_012388166 227 TSIRDKEEGADLLMVKPGMTSIDLIGPIKDKT-G---LPTGAYQVSGEYASLVYLAKEGFLN---FEDGLRETWDVFRRA 299 Leptospira biflexa
Q8EY45       227 SSIRDKEEGADFLMVKPGMTSIDLIGPIREKT-G---LPTGVYQVSGEYASIHYLSQNGFCD---FDSALSETWQIFSRA 299 Leptospira inte...
1I8J_B       304 GADLIFSYFALDLAE 318 Escherichia coli
XP_001609639 463 GADLIVSSFAKDVAQ 477
Q8IL68       411 GANIIITYFAKQYgl 425 Plasmodium falciparum 3D7
XP_003171517 334 GADAILSYFTPDFLD 348
EFR02786     332 GADAIVSYFTPEFLD 346
XP_002618428 401 GARLFISYFTPEFLE 415
CCH61216     322 GAGLIISYFTPEFLD 336
Q6C0Y3       322 GANLLISYFTPDFLE 336 Yarrowia lipolytica
WP_012388166 300 GSSFLITYGARIAqr 314 Leptospira biflexa
Q8EY45       300 GASYLITYAARRGke 314 Leptospira interrogans
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