Conserved Protein Domain Family
DUF4699

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pfam15770: DUF4699 
Domain of unknown function (DUF4699)
This family of proteins is found in eukaryotes. Proteins in this family are typically between 303 and 319 amino acids in length.
Statistics
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PSSM-Id: 464858
Aligned: 21 rows
Threshold Bit Score: 247.725
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_015141168  45 IQSYIFDPEELQSPGCTHEGNSYKQDEQRSNKFKFKQNCEIKEQKKEIQKDELKGTGIKNRVNSTGETLWNHRGDAFQDD 124
XP_007496640   9 IQSYFFDPVHAPPAGYINEVNNYKLEEEDGIKVKGKENNEILVQKNDLQNEELKRTETKNRLNSTQEPFWHHRGPPPPED 88 
XP_005045436   9 IQSYIIDPEEVQSSGCIHEVNSYKHKEQGSNKSKFKENCENEDPKNELQKDEVNKTENKNPVNSTTESLWNHRGNDSHED 88 
XP_020956755   9 IQSYLFDPVQVPSPGYVNEVNSCKLDEDDTVKLKGRQSGEVLVPKSDLQSKDSVRTASTSGQDAPPEPCRPPQGPLPHGD 88 
XP_005207911   9 IQSYLFDPVHVPSPGYVNEVNSCKLDEEDTLKLKDKQSSEILVHKGDPPNEGSKRTASGSGTAAPQEPYGPPRGPLLSED 88 
XP_005319960   9 IQSYLFDPVPVASPGYINEVSSCKLDEEDPVKLKSNQSSEILVHKNVLASEGFKRTEGRGQRAGPQEPCWPHQEPLPQED 88 
XP_013009968   9 IQSYLFDAVQAPSPDYVSEVSSTKLDEDHTDNLKSR-SSEVLVHKNALWGEGLRRTESRSREAGPQEPCGPPQGSLPQGY 87 
Q6AYA8         9 IQSYLFDPVQVPSPGFVNEVNNCKLEEDDTVRLKGTQNSEVEVPGSTLHSGSLSKPDSSGSTTG-----LPCQGSLTQED 83  Norway rat
EGW11112       6 TPSYLFDPVQVPSPGFVNEVNNCKLDEDDTVRLKGTQNSEAEVPRNALHGESLTNTENRDGTAG-----LPHQGSLPQED 80 
XP_008273146   9 IQSYLFDPVQVPSHGYVNEVSSCKLDEDNTVKLKGKQSSKVLVHKSDLQIEGLKWTESKGRQDGFQEPCWSHQGPHPQGA 88 
XP_015141168 125 SLVK-CVAKHDVAVNGSNSHAGVHPI--------LSPSTNSAKEASEQSts-sqPAElSSVNTGDFHSKPNECGQELDLG 194
XP_007496640  89 DSGNsVA-KSDAPLNGISSSPAVSPSvhaslsyrKEITPEESGSGSWAS-----ASS-EGDPVEHFVKESDPGRKDPKPR 161
XP_005045436  89 GLVN-CAAKLDVAVNGGNSCA-QHSM--------LNPNTNPVKETSEKGts--sQSEaSSASNRDFYTKSNRSWQELDLE 156
XP_020956755  89 PAGGpCAEKPGSAVNGLGPATALQLP--------GDPKLPQGDGGSQAS-----RAN-RVPQSQPFLEGDNARALDCVLL 154
XP_005207911  89 TVGGpCAEKTSGAINGLGPAAVLQLI--------GEPGPPQGARDSWAS-----AAN-KGHPTQPFLEGGSARELDCMQL 154
XP_005319960  89 AGGGrWEEKPGSAVNGMGPTAALQPT--------RNPRSHQRDKGSRAS-----PTD-SVHPTQPFLEGGDTRKQDCVLP 154
XP_013009968  88 PGEGlCT-KPGGTANGIGPSASPESS--------RNLWPHPGPMGSWAS-----TAD-SLHSAQPFLEGRDTGSQDCVPP 152
Q6AYA8        84 SEERpCVEKHG-IVNGIRPTATLQSV--------RSPRPQQVDSVSWASspwvaTID-SAHPAQPFLEGEDYRKQSCMLP 153 Norway rat
EGW11112      81 SEERhCVEKHG-IVNGISPTATLHLV--------RSPRPHQVDSVSWASspwegTID-STHPAQPFLEEEDCRKQSCMVP 150
XP_008273146  89 PVGGqCAEKLCGTANGISPT--------------GNSRPHEGDQGSWAS-----TAD-NSHPTQPFLEGGDARREDSVLL 148
XP_015141168 195 ------AGSHRKADCS-----QTNSIRgvkpwsiedsnflkgSAVLETQNNdAIKLPDIDYCQNGNQI------RNYVEK 257
XP_007496640 162 ap--eeTRVTSNGNSQasgenASSPGS---------------HHTLEVQDH-LIPLPVPDYPQVEVQAin--qiVD--EN 219
XP_005045436 157 ------TSSRSKAASS-----VPNSIPdsqtaed--tvflkgNSILETENN-AIRLPEIDYPQNGNQT------GNYVEK 216
XP_020956755 155 al--eeTQVMGDGDSR-----APSTAG---------------HPPREVQDH-GLRIPTPDYPQFDGPAed---sVDGEEK 208
XP_005207911 155 gs--geTQVIRNGGSG-----TPSTAG---------------LAAWEVPAQ-VLQIPTPDYPPFSSSAedntdhVDHQEK 211
XP_005319960 155 al--ekTQVFQSGDFE-----VPSKVE---------------SFALEVQGH-DLQIPTPDYPQLWGTAvh---nVDHEEK 208
XP_013009968 153 as--geTPAVGRGGCR-----APAEAE---------------SPVSEGQAH-IPQLPVPDYPQLWDPAgd---sEEQEEK 206
Q6AYA8       154 tl--egTQMVGHGDSR-----APAEA-------------------LAVADH-IPYIPAPDYPQVWSPEvd---nVNPEEK 203 Norway rat
EGW11112     151 ts--eeTQMVAHGDFK-----APAEV-------------------LAAADH-VLHIPAPDYPQLWNPTvd---nADPAEK 200
XP_008273146 149 vseqeqTQVPRNADSG-----DPSQTE---------------CIAPEEQGH-ILQIPAPDYPPLWGPNad---gVDHGNR 204
XP_015141168 258 DSISVNYTHPDQMNK-HLAMQGQDLHVTPPL--Q-TKESSIEPFNTD--SAGLSEDIPNGIAAMAVPTAAQAPTHHSHRD 331
XP_007496640 220 DCFLSNHIMVEQMDRvDYASGDHLSNLCFSK--RrSWDSFHEAIKTEalTMNFNED-----VSERDTDWGPE-------- 284
XP_005045436 217 DSFSVNCAHSDQNTG-ASAIQDQDLHVIPPLpvK---ESSIESFKTD--SASLSESLTGGITAVAVTKVAQAPTHTSHKG 290
XP_020956755 209 DCLFESPSEEEPQEGtYPRAREQGLNMPFSV--KrSWDSLNEAVATEilSAYFKED-PTQDVPAVDSRNGWQEAPGSPED 285
XP_005207911 212 DRLFKIHSEKEPQEGaHPPAGECGLNMPFSI--KrSWDSLNEAVTTEipSVYFDKDDPAQDVPVVDSRNGWEEAPGSPGD 289
XP_005319960 209 DYLFKNPKEDEPLAGiLPRVGEQGLNVPFPR--RrSWDSLNEAVTTEvlSIYLKEQGPV--TPVVNSRIEQEKTDDSDGN 284
XP_013009968 207 DCLFETHAENEPLAEvHPGLTEYELNIPFPM--QrNWDSLNEAVATEvlSIYFNEKGPAQVVPIADSRSKQMPAQGSEGD 284
Q6AYA8       204 DCLFENHSEVEPLPGiHPRVSQQGLSMPFSL--KrSWDSLNEAGTTEvlSVYFKEEDPTQPTPVADPGNEREDPHTYNGN 281 Norway rat
EGW11112     201 DYLFENHPEVESLPGiHPRMSEQGLSLPFSL--KrSWDSLNEAVTTEvlNVYFKEEGPTHPTSVVDSRNEQEVPHPYNGD 278
XP_008273146 205 DRLFQNPPELERLQGs----GVQGLGAPFSM--KgSRDSVNEGVAVEgrSVALADEGPALLVPVADSGDEQEDALGSDGD 278
XP_015141168 332 INGQTEEEDAEVAAALAALEAATAGEDLEEDD 363
XP_007496640 285 ------QEDAAVAEALAALEAATAGEDGEEGD 310
XP_005045436 291 VNGGIEEEDAEVAAALAALDAATAGEDLEDDD 322
XP_020956755 286 RSGEPAEEDAEVAEALAALEAATAGEEVDEVD 317
XP_005207911 290 GSWETADEDAEVAEALAALEAATAGEDVDEAE 321
XP_005319960 285 RDGEVVDEDAAVAEALAALEAATAGEDLDEAD 316
XP_013009968 285 SEEEEEDEDEAVAEALAALEAATAGEDEDEAD 316
Q6AYA8       282 KEGAVVDEDAEVAEALAALEAATAGEDADDAD 313 Norway rat
EGW11112     279 RDG-VVDEDAEVAEALAALEAATAGEDADEAD 309
XP_008273146 279 GGGEILDEDAAVAEALAALEAATAGEDVDEAD 310
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