Conserved Protein Domain Family
LRR19-TM

?
pfam15176: LRR19-TM 
Leucine-rich repeat family 19 TM domain
LRR19-TM is the single-span transmembrane region of LRRC19, a leucine-rich repeat protein family. LRRC19 functions as a transmembrane receptor inducing pro-inflammatory cytokines. This suggests its role in innate immunity. This family of proteins is found in eukaryotes.
Statistics
?
PSSM-Id: 464545
Aligned: 8 rows
Threshold Bit Score: 138.502
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
XP_003782893 256 NLTRDSEHGPLGKSWAFLVGVVVTVLMTSFLIFIAIKCPIWYNILLSYNHHRLEEHE---VETYNESFNGNPSSFSQISA 332
XP_005334245 256 NFTRNSEHEPLGKSWVFLVGVVVTALMTSLLILTAIKCPIWYNFLLSYNHRRLEEHE---AETYEDGFPGNSNSLPHIGD 332
Q8BZT5       250 NLTWTSEHEPLGKSWAFLVGVVATVLLTSLLIFIAIKCPVWYNILLSYNHHRLEEHE---AETYENGLTRNPSSLSQITD 326 house mouse
XP_007498146 257 NKTKNAESEPSGKSWALLVGVVVVVTVTSMLIFIAIRCPTWYNFFFSYNHHRLDEQE---ADTYEGDFTVYPNSLPQTPD 333
XP_003431607 256 NL-KNSERKLLGKSWALLVGVVVTVLMTSLLIFVAIKCPIWYNFLLSYHHHRLEEHE---AETYEDGFTGNSSSLSQVPD 331
XP_003407373 256 NLTRNPEHERFGKSWAFLVGVAVSVLMTSLLIFIAIKCPLWYSFVLSYNHHRLEEHE---AETYEDGCTGNPSSLSPAPN 332
XP_005050250 250 TALPAVKGGRSWPYLVGFIVTAIGISILIALAAKCKLAHKNFASYRHRPLPEISSIGgspMEDTSSWDRGSIPDAADLQA 329
XP_008107673 245 TSTSTPPLEKTGRSWPYFAGFILLAAGISILIALVAKCILLRRNRASYQHQRLPDSRsvgSSHAEEADMGVAYGRNPPGA 324
XP_003782893 333 TNPEDTTVIFERLHSFVVDDDGFIEDKYIDTHELCEEN 370
XP_005334245 333 INSEDTTVIFEQLHSFVAEDDGFIEDKYIDTHELCEEN 370
Q8BZT5       327 TNSEDTTVIFEQLHAFVVDDDGFIEDRYIDINEVHEEK 364 house mouse
XP_007498146 334 TNPDDSIVIFDQLSSFMVDEDGFIEDKYIDTQEMREEN 371
XP_003431607 332 TNSEDTTVIFEQLHSFVVDDDGFIEDKYIDTHELHEEN 369
XP_003407373 333 TNSEETTVIFGQLPSFAVDDDGFIEDKYIDTHELHEEN 370
XP_005050250 330 EDDD--------------GFIEDNYIQPSEQLPTKEER 353
XP_008107673 325 GCPAD-------------DDDGFIEDNYIEPNRDMREE 349
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap