Conserved Protein Domain Family
DUF2400

?
pfam09674: DUF2400 
Protein of unknown function (DUF2400)
Members of this uncharacterized protein family are found sporadically, so far only among spirochetes, epsilon and delta proteobacteria, and Bacteroides. The function is unknown and its gene neighbourhoods show little conservation.
Statistics
?
PSSM-Id: 430745
Aligned: 119 rows
Threshold Bit Score: 205.074
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
WP_013667867          24 DPICIPHQFSVKQDVEIMGFFAAVLAWGQRKTIINKCRELIDRMDGKPYAFII--GHE-PDDLKG-LLG-F---K--HRT 93  Sphingo...
CBG39713              24 DPIMVLKEYAEHKHFELIALTCALFSYGNARQIVKFLRAL---------DFDCldKRTlKHVIFPh-----------YRF 83 
EES89271              24 DPLGVARQFMS----DKVALFCALFAYGNARAIVRFLESC---------NLYFldQASyKSHHNLhLNEiPyctNkpYRF 90 
Q7MSP2                29 DPLLVAQKTKS----DLGALICALFSYGSAKQIVTFLETL---------DFSLlaQTPqSIQNAPfg---------vYRF 86  Wolinel...
instpast:LEPBI_I1933  28 DPICFPKQYKNPLDIELVSLISCLFAYGNVKNIQNFLKPIFLEMGPSPYEFFVysNPSfSKFLNS---------QkgYRF 98 
Q8F7U6                28 DPVEFPHLFSDLRDREISGFISALFSYGNITAIKDHLKRIFAICGNSPYRFLL--NEDlKSIRKN-LKS--------YRF 96  Leptosp...
BAI80635              21 DPIIYPHTIKG--DIEFIAFISSIFAYGRVASINKFLKLFFDLYGFYPNRVKTkkNIY-------------------YRF 79 
jgi:Flexsi_0897       44 DPIIFPSTIEG--NKEYISLVSSLFAYGRVNSIQDFLKKFFYRYGNDPFDT----DNSeAKLY--------------YRF 103
jgi:Calni_0369        49 DPIFFPSSYSG--NKEYVAFVSALFAYGRVNLIKDFLIRFFDYYGNDPNNNLVqeSSSvY-----------------YRF 109
tigr:THEYE_A0866      24 DPIRFPKRYKNPLDIEIAGIIASFFAYGNIKSFCNFLEGLFNIMGQHPSEFIL--NFNpSSLMKK-LE--I---K--YRF 93 
WP_013667867          94 FNDTDLLYFVSFFRAHYE--RFNS--LEDAFLPssmssefredflmegqeeAVSSQEMssnvcyqtelirpnlkvEDALN 169 Sphingo...
CBG39713              84 QNAHDVQMFFEILQKIGA---SGG--IKAVMLEgyyq-----------akqSQGQEGI-----------------LRAIG 130
EES89271              91 QNQDEIQDFFESLLMSGD--------LYEIFYRa------------------yKKDSL-----------------LKGIE 127
Q7MSP2                87 QNSEDVRQLFLALSTLDD--SPQA--LRSIFLEg------------------hKKGGI-----------------LEGIK 127 Wolinel...
instpast:LEPBI_I1933  99 QTKEDVIVLFLTLQRILTkkKQTSplFESYFLDtngr-----------------------------------fdqNTSIQ 143
Q8F7U6                97 QKPEDTYLFLQTIQNKLR--TTEGhgLESLFSLpeegefqf---ssrdqksFLEGGSL-----------------RRRIL 154 Leptosp...
BAI80635              80 QSSDDIYNFLNFLKNIFQ--SYGS--LYDFLLK-------------------INPNDL-----------------DAAYK 119
jgi:Flexsi_0897      104 QTAEDIRLLVTMIKGIYL--QYGS--VQNFFVN--------------------ISDSL-----------------EKALE 142
jgi:Calni_0369       110 QTSKDIFNLYGMITEIYE--KYGS--IEGAFLS--------------------FSDEL-----------------EEALK 148
tigr:THEYE_A0866      94 SSVYDVVAFLFILKKLIQqsPIKS--LEYYFQS------------------------------------------DSHIQ 129
WP_013667867         170 RFRAYFFS---LPDy-----PTRTRK---HISSP-AQKSTCKRLNMFLRWMVR-NDlrGVDFGIWKR-IRMSELICPCDV 235 Sphingo...
CBG39713             131 KCIEKMYaq---------ikQKPSRGlehLLGSRgASKSPLKRYNLFLRWMVR-KD--KIDFGCWRE-FLPSDLILPLDV 197
EES89271             128 ALQNYLYSn----------lKKTTKSlefLIGKS-QSNSPLKRWNMFLRWMVR-KD--CVDLGLWEG-IKRSDLILPLDT 192
Q7MSP2               128 TMQRAILErs---------gGYQSSGfrfLIGNPeAHQSPLKRWNMFLRWMIR-KD--CLDLGWWEGvILKSELILPLDT 195 Wolinel...
instpast:LEPBI_I1933 144 NFQKHFET----EListlktETLSYGlqfLIGKW-KSKSPKKRISLFLRWMVR-ND--YPDFGLYQN-IKPNQIPYPMDV 214
Q8F7U6               155 SFQLRFLK----ESskidskQTKSYGykfLVGQG-IRSTSLKRYSMFLRWMVR-KE--FPDFGIYSS-ISPSELQFPLDV 225 Leptosp...
BAI80635             120 GFHEYYLEyf---------gNKLTQGlrfLLPDI--TKSSAKRVRMFFRWMVR-KD--NIDFGVWVK-YDKKSLKFPLDI 184
jgi:Flexsi_0897      143 GFLDYARGfg--------aeNNAGRGyffLFPKY--GKSGLKRLRMFLRWMVR-KD--DVDFGLWGA-YKTGELLYPPDT 208
jgi:Calni_0369       149 RFVLYCREfg--------rkRLLDRGffqLFPDP--ESSGLKRFRMFLRWMIR-KD--EIDFGLWKN-FDRKDLIYPIDT 214
tigr:THEYE_A0866     130 KISNFVQSafkVNLkpiygkNIKTKGllhFFPDP-LKGSPCKRINLFLRWMVRkRD---IDFALWNT-IKPSELIIPLDV 204
WP_013667867         236 HVERVARHLGLITRKQTDWNTAVELTDNLRLLDANDPVKYDFALFGLGVE 285 Sphingobacterium sp. 21
CBG39713             198 HTFMVSRKLGLLERKTCDLKSALLLTDVLKQYDSKDPVKYDFALYRIGQE 247
EES89271             193 HTFRVSQRLGILKRKSYDLKAALEVSEFLKKLDLNDPIKYDFALYRIGQl 242
Q7MSP2               196 HTFALCKKLKIIQRQSYDLKAAIEATEFLKKLDPHDPIKYDFALYRLGQE 245 Wolinella succinogenes
instpast:LEPBI_I1933 215 HIQKLIKVLGIKNQKQIQLNDAFLLTEFFKKINSNDPLLYDFYLTRVGIi 264
Q8F7U6               226 HIQRIASVLNLSSRRSSDWKKAEEVTDFFRAIFPDDPVKADFALSRLGIL 275 Leptospira interrogans
BAI80635             185 HILTYAYNRNIIRNKSNSYKNTLKVTDYFLKINEIDPVKYDFALTRLGMI 234
jgi:Flexsi_0897      209 HILRFAKNFGIISSEANSHRNARLITDYFKTIDKQDPVKYDFAITRLGML 258
jgi:Calni_0369       215 HILRFADKNGIVSNETNSLKNALKITEFFRGINSSDPLKYDFTITRLGMi 264
tigr:THEYE_A0866     205 HIWRVSKKLGFTKRNTQSIKTAMEITEYLKKIEPEDPLKYDFVLCHGDIN 254
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap