Conserved Protein Domain Family
G8

?
pfam10162: G8 
G8 domain
This domain is found in disease proteins PKHD1 and KIAA1199 and is named G8 after its 8 conserved glycines. It is predicted to contain 10 beta strands and an alpha helix.
Statistics
?
PSSM-Id: 462971
Aligned: 135 rows
Threshold Bit Score: 74.1794
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
EDQ93048                      1741 TWVNDEPPIEGDTVVIPADQVVLMD-VTPPK----LFLLLVQ--GQLIF-EDmQDLELHASYIWVQGg-LLEVGTEDVPF 1811
Q22PG1                        1813 TWGGSFAPIAGDLVYVAQGKSIIIDvPYIGI----LNTIVVSn-ANLIFaND-KNIHLEAYNILVQNg-NVIIGTQSSPV 1885 Tetrahymena thermophila SB210...
WGS:AAGF:cds.TTHERM_00138590A 1810 TWGNDFAPIDGDLVYVTKGRNLIVDvPYVGV----LNTVVVDn-ASLIFaND-KNIHFEAHNILVQQg-RVIIGTQASPV 1882
EFA86780                       391 TWGAAGVPSPNTNITLPANTKVLVS-SCSMSstqvYQKIVVPatSELIF-MD-ANMTINFRDIYVQg--KLIMGTTQCRY 465 
EFA80459                       586 TWGGA-VPSASSTITLPANTKVLVS-SCSMSstlvYQKIVVPagSELIF-MD-ADMTINVRDIMVNg--KLIIGTPLCRY 659 
Q2SGK1                         229 SWLENSVPGPGDEVYIPAGAAIALDnLNAAN--------VIIneGILTApVN-RDFTLDVAEIHVMAggLLELGREEATF 299  Hahella chejuensis KCTC 2396...
A0E164                        1809 TWEYK-VPKDEDSVLIKNYQKVLLD-VNTKQ----LERLIIE--GTLIF-ADeQDTKLIANSIILREg-SLIIGSQDQPY 1878 Paramecium tetraurelia...
A0BH93                        1843 TWGGYVFPSDGDSVMVYQGATLIVD-VHTPK----LVQVLVE--GNLVFaDD-ADTSLDAQYVVINRg-TFQIGTQEVPH 1913 Paramecium tetraurelia...
A0D5V3                        1868 TWGGYEYPGDGDSVIVNAGQTLIVD-VKTPK----LMQLLVE--GTLTF-SDeLDTSIDAHYIVIREg-KFNIGTELIAH 1938 Paramecium tetraurelia...
XP_001007450                  1789 TWGNDFAPIAGDIVYVNNGKSLIVDvPYVGI----LNTIVIQn-ANLIFaNN-MNIHLETNSILVQSg-NVVIGTQSSPV 1861 Tetrahymena thermophila SB210...
EDQ93048                      1812 QHRATITLYGd-RWNSIGLPHLGAKCLVATNaanymglygghdgaavpatlrGVIDIHG-IPRRRTWTKVA 1880
Q22PG1                        1886 TGNIRITMHG--NINDQQFPTVGSKGLSIYN---------------------GSIDIQG-KPRAVTWTELS 1932 Tetra...
WGS:AAGF:cds.TTHERM_00138590A 1883 TGNIRITMHG--TQDEKQFPTVGNKGLSLYN---------------------GSLDIQG-ALRPVTWTELS 1929
EFA86780                       466 NARINLIFSGakTLQDNIAPFLGTKGIGVAQn--------------------AFISMHGkQYHN-TWTKLA 515 
EFA80459                       660 NGKINIIFNGakTLTDTIGTFFGSKGIAVSSq--------------------GFLSINGkQYHN-TWTKLA 709 
Q2SGK1                         300 NGQGVITLLG-------DNPAAESKLIHAMNg--------------------GRIEMHG-QPRL-SWTQLG 341  Hahel...
A0E164                        1879 QHQAIIMISG--RETDFQFPLIGNKVIGCIK---------------------CQIQMFG-KQRTFTWSFLD 1925 Param...
A0BH93                        1914 QHKVEITIRG--EERGVQYPNMGNKMIGCNE---------------------CQIDIHG-RDRTPSWTLLS 1960 Param...
A0D5V3                        1939 QHKVQITLYG--DEQDVQMPEMGNKVLGCHQ---------------------CQLIIHG-KERTPTWTLLS 1985 Param...
XP_001007450                  1862 TGNVRITLYG--QQSDKQFPTVGNKGLSIYN---------------------GSIDIQG-QTRAVTWTELS 1908 Tetra...
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap