5N08,1XD7,1YLF


Conserved Protein Domain Family
Rrf2
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pfam02082: Rrf2 
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Iron-dependent Transcriptional regulator
Several proteins in this family form iron-sulfur clusters enabling iron dependent DNA transcription regulation. The iron binding is mediated by three conserved cysteine residues. Members of this family can also bind O-acetyl-L-serine, [Fe-S] and nitric oxide (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Links
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Statistics
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PSSM-Id: 396591
Aligned: 99 rows
Threshold Bit Score: 84.5264
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
5N08_D   3 LTKFTDLALRSLMRLAVVRdgDEPLATREVAEVVGVPYTHAAKAITRLQHLGVVEARRGRGGGLTLTDLGRRVSVGWLVR 82  Streptomyces coelicol...
Q7NKV7   4 ITRQSDYGIVLVSHLAAHP--ERSFGAPELAAQVNLPLPIVRKILKLLAREGLLVSQRGVKGGYCLALPPAVISVADVVT 81  Gloeobacter violaceus
Q83BX6   4 ISRLADYATTVMTILASGK--TERYSAAQIARTTPLSAATVSKVLKLLNEGKLVNSERGVNGGYQLARAPQSISIADIIT 81  Coxiella burnetii
Q8P749   4 VTKLTDYATVVLTVLAARS--DQVLSASELAEQAGLEAPTVSKILKPLSQAGLVEGLRGVHGGYRLARAASAITLVEIVE 81  Xanthomonas campestri...
Q9PDA2   4 VTKLTDYASVVLTVLAAHP--GAVLSANELAEHSGLEPPTVSKILKPLSQAGLVEGRRGAYGGYRLAHPPGEITLIQIVE 81  Xylella fastidiosa
Q82NE1   3 MSGGVEWALHCCVVLTSVE---EPVPATRLAELHDVSASYLAKQLQALSRAGLVRSVQGKAGGYVLTREPASITVLDVVE 79  Streptomyces avermitilis
Q92S81   3 LGDGVEQAIHSVTMLSCLQp-GSTLSAAALAEFHGVSTSYLLKHLQAMSGAGLLEAVPGPKGGYRLARAPEKITLLDIVL 81  Sinorhizobium meliloti
Q8ETE1   3 FSKATNYALHTMVYLADIPk-GTSIGVDRLAETQKLSPTYLSKILTKLVKSGLIESTPGAKGGYRLARKADNITFLDVIR 81  Oceanobacillus iheyensis
Q92E21   3 FSKATNYALHTMVYLANLSp-EKSVGVKELATKQNVSPTYLSKVLTMLVKAGFVESVTGVNGGYKLAEPASSISFLDVIQ 81  Listeria monocytogenes
Q8KF07   4 VSRKFEYGLHAVTYLAMKGp-EQVVTVKELAAEIGFSQVFLAKAMQSLNKAGITRSVQGVKGGYTLARPAEQITVADIGV 82  Chlorobaculum tepidum

5N08_D  83 ELEGEAEVVDA--------EGDNPAPLRGAARLRRALRDAQEAFYAALDPLTVTDLVAA 133 Streptomyces coelicolor A3(2)
Q7NKV7  82 ALEGPIALTECie-----dAPGGGCAHEAVCPLMPKWQRINAVIQQALSGISLSELIAP 135 Gloeobacter violaceus
Q83BX6  82 AVDGKPAMTECs-------RDANRCEHNAVCGVRENWQLINTLIFDVLDSLNLADMQKP 133 Coxiella burnetii
Q8P749  82 AMEGPLAITECs-------QDHSQCGIAHQCGVRSNWRLINDVVGDALRRVTLAQMLHP 133 Xanthomonas campestris pv. campestris
Q9PDA2  82 AIEGPLAITECs-------QDHNQCSITHQCGIRSNWQLINTLIAQALRSITLAQMLAP 133 Xylella fastidiosa
Q82NE1  80 AVDGPDQAFTCteirqrgpLATPAESCAVPCAIARAMTGADAAWRAALRAVSIADLVQN 138 Streptomyces avermitilis
Q92S81  82 AVEGPEPAFRCneir-lrgPNPYSCKPAAPCTINVAMLRAEQAYRAELRRVTIAAIMAD 139 Sinorhizobium meliloti
Q8ETE1  82 AIEGQTVLFYCs------iDHDDDFSRNEECLIENAMIEAEEKMKESLDRKYIVDIAKL 134 Oceanobacillus iheyensis
Q92E21  82 AIEGKGAFFHC--------DPKNHSESQPHCLIGEVMNKAEQQMEDYLSKQTVGSIVVE 132 Listeria monocytogenes
Q8KF07  83 AIEGEPHLMRCs-------QENCQCEIESNCTHKGYMLNLQKRIYDLLAETTVAVLLER 134 Chlorobaculum tepidum
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