Conserved Protein Domain Family
DUF1848

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pfam08902: DUF1848 
Domain of unknown function (DUF1848)
This family of proteins are functionally uncharacterized. The C-terminus contains a cluster of cysteines that are similar to the iron-sulfur cluster found at the N-terminus of pfam04055.
Statistics
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PSSM-Id: 430302
Aligned: 106 rows
Threshold Bit Score: 286.332
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CDE40946        25 VSASRSTDIPAFYADWFFYRLdKAGYSAWTNPFNGVK-SYVSY--KDTRFIVFWSKNPRPLLR---YLPILKQR-EIGCY 97 
WP_015878489     3 ISASRRTDIPAFYSDWFMNRI-KAGFVMTRNPFNSKQiRQISLlpADVDVIVFWTRNAFPMLK---HLNLLDEM-GYRYY 77  Tolumonas aue...
jgi:Ppro_0347    4 ISASRRSDIPAFFAHWFMERV-RQGFFHRVNPFNAHQvKAISLrpEDVDAIVFWTKNPKPLFP---FLAELDDR-GLNYY 78 
Q3AA92           4 ISASRRTDIPAFYGEWFMNRI-REGYFIFKNPYNAKQmSKISLrpEDVTAIVFWTKNPAPFMK---YLDELQDR-GYRFY 78  Carboxydother...
jgi:Dehly_1162   3 ISASRRTDLPAFYSEWFINRI-QAGFCCVVNPLNAHQvSRVSLkpEDVTAIVLWSKNPAPLIP---SLPILDRM-GYRYY 77 
BAL99065         3 ISASRRTDIPAFYAAWFMNRV-RAGYCAVPNPFNPRQvSRVSLrpEDVDVIVFWTRNAQPLMA---SLDELDDR-GYRYY 77 
ESQ13424         6 ISASRRTDLPAFYGEWFMNRV-HAGWCAVPNPFNPKQvSRIELdpLDT-LLVFWTRWPAPFMQ---AAAELRSL-GFRYY 79 
WP_004071389     8 LSASRRTDIPGWYTPWFLDQI-EKGYFFVTNPFN-RQsRRVDAtpKEIHTIVFWSKNYGPFLDl--SAHKILAQkGFHLF 83  Desulfobacter...
jgi:Dole_2978   28 LSASRRTDIPAFYMEWFMAGI-DRGLFEVTNPYN-GVvRQVECtpESVHTIVFWSKNFGPFLDg--RFGETLAGeGYHLF 103
ACL05962         9 ISASRRTDIPAFYMDWFMAGV-KQGFFEVQNPFS-KImHKVPAdnEAVHSIVFWSKDYSPFLRggyGTALIDT--GYHLF 84 
CDE40946        98 IQYSLNDYEEEgLEKNVPPLKQRIETFKQLTNALGKGHVIWRFDPLVLTDN----INIDKLLDKVENIGNQLL--GYTEK 171
WP_015878489    78 FQYTITGYPRA-LETTTLHPLKAIDNFIKLSQQIGKEKVIWRYDPILLCNL----LPAEEHIRLFSRIAGLLR--GYTTR 150 Tolumonas aue...
jgi:Ppro_0347   79 VQFTLNPYERS-FEPNLPSLSERIHTFRTLSEMIGPRRLVWRYDPLILSSR----TPLEYHREMFDRMATELR--GASLR 151
Q3AA92          79 FQYTLNGYGPE-MEPFLPSVEKRIKTFKKLSEKIGKEKVIWRYDPVIFSNV----HSSDYHREKFSYILNELK--DFTTR 151 Carboxydother...
jgi:Dehly_1162  78 FQYTLNDYSND-LEQRIPPFHQRLDTFKSLANKIGQQRTIWRYDPIIFSPS----LDESYHLDRFNKIATELN--GSTNR 150
BAL99065        78 FQYTILAYPRL-LETKTPPIEAAIETFRRLSERIGPERVIWRYDPIVFSSF----TDAAFHRERFAWLAGQLR--GLTRR 150
ESQ13424        80 VHYTVLDYPPA-IHAKAPGLEQTIGAFLNLAEMIGPERMVWRYDPILFSAN----TDGEYHLSRFAQIARRLQ--GATKR 152
WP_004071389    84 FNFTINTPLKD-LEPGLPDLSDRLAQARRIARDLSPVQLAWRFDPICFYEKgg-rMFNNL--DAFEDIAGKLAqmG-IKQ 158 Desulfobacter...
jgi:Dole_2978  104 FNFTVNTEDRL-LEPNLPPLDQRLCQLDALARRFGPERVQWRFDPICFYSAgnggFKNNL--ADFPKIAKAATeaG-IGR 179
ACL05962        85 FLFTINSESPI-LEPRTPPLANRLAALKKLAEQFGPEAVTWRFDPICHFATeq-gPQNNL--GDFVAIADAAAacG-VAR 159
CDE40946       172 LVFSFADIlsYRKVQANLqka------ninYVDWQEDQM----R----------EFAQRLSAFNHKWDYELATCGEKId- 230
WP_015878489   151 VVVSFADF--YKKTERNLrgvg-----dltVSDITQNRE----Qy--------sELSKALSQIAAAHEMEIFSCSEKVi- 210 Tolumonas aue...
jgi:Ppro_0347  152 VMFSFLDF--YGKARGRLrg--------iqREQGVVIQD----VrgegfaaerwRLLADMRASAEDNGMELCSCAEAEe- 216
Q3AA92         152 VVISFVDE--YRKATi-------------nFKKLKEEGI----EiyqppeviikSFAYFMAEEAKKLGLEIQSCAENIay 212 Carboxydother...
jgi:Dehly_1162 151 VMISILDM--YDKVSNRL---------------EKQGQYfntaYspdppggkllTFLRELHDIAGTNGMEIFSCAEETd- 212
BAL99065       151 VVISVVDG--YRKVQARLrklv-----aqgATIPDQSPE----Qiad-----fdELMHSLVETAMRCEMEIVSCAEELd- 213
ESQ13424       153 VVISILEP--YQKAARRLarlaq---tqpaYRYLEYDAA----Rd--------aDLLRHLVRIAHEHGLKIHSCAEQHd- 214
WP_004071389   159 CITSFYDP--YKKVAARIkrmaesgrpmlkFIDPGMDRK----T----------KIIRSMAQSLKHLGMDLFLCCEKEl- 221 Desulfobacter...
jgi:Dole_2978  180 CVTSFLDL--YAKVKKRAara------gvtFMEPGMEKQ----V----------EIVTRMADLLKGCGIALHTCCEKEl- 236
ACL05962       160 CVTSFVDV--YRKLVTRTkvlk-----nfsFAPPGPERQ----A----------EILLRMQTVLQDRGITLYTCCENR-- 216
CDE40946       231 LTEY-----GVQKN----HCVDDNLIIRLAyddkilmdylkvkqhpmpqvglfgdaeplpqdaivlpngmyathgdnRDK 301
WP_015878489   211 DPEH-----DIPHG----ACIDAALIEKLFhlhl----------------------------------------svkKDK 241 Tolumonas aue...
jgi:Ppro_0347  217 LERI-----GIRHG----HCIDGGLVRELFgnrg----------------------------------------nfsKDK 247
Q3AA92         213 LPAA-----GIMPG----KCIDADYIEKVFsltlp-------------------------------------eklhlKDK 246 Carboxydother...
jgi:Dehly_1162 213 FADA-----GIQHG----HCIDTDLIRQLWhlpi----------------------------------------kfkKDK 243
BAL99065       214 LTRY-----GVRPG----KCVDDALIARVFnlnl----------------------------------------tlkKDA 244
ESQ13424       215 LASV-----GIAPG----KCIDDQLIQSVFgvqv----------------------------------------shkKDK 245
WP_004071389   222 META-----GLQAYaspnACINGHLYKALFggnp----------------------------------------etrGDY 256 Desulfobacter...
jgi:Dole_2978  237 MAGLag-nvPVTAS----ACINGRLFMENDggvv----------------------------------------pvqKDR 271
ACL05962       217 LEGIlpkdcGILPH----ACINHDLLEKLYgpgl----------------------------------------skkQDK 252
CDE40946       302 GQREF--CGCIKSKDIGEYN--TCVHGCEYCYA 330
WP_015878489   242 NQRTE--CLCVQSVDIGAYN--TCVHGCQYCYA 270 Tolumonas auensis
jgi:Ppro_0347  248 YQRKE--CGCVESVDMGAYN--SCPFQCVYCYA 276
Q3AA92         247 SQRQE--CGCVVSKDVGVYD--TCLHGCKYCYA 275 Carboxydothermus hydrogenoformans Z-2901
jgi:Dehly_1162 244 GQRKA--CGCSVSKDIGANS--TCLHECVYCYs 272
BAL99065       245 GQRDA--CGCVTSRDIGMYD--SCLFGCQYCYA 273
ESQ13424       246 SQRDA--CGCVESRDIGIYD--SCAFGCAYCYA 274
WP_004071389   257 GQRRKkgCQCTKSFDIGSYEdhPCFHNCLFCYA 289 Desulfobacter postgatei
jgi:Dole_2978  272 GQRAGagCGCTESIDIGSYAqhPCYHSCLFCYA 304
ACL05962       253 GQRASqgCRCMESRDIGSYSlhPCRHSCLYCYA 285
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