2I0Q


Conserved Protein Domain Family
TEBP_beta
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pfam07404: TEBP_beta 
Telomere-binding protein beta subunit (TEBP beta)
This domain represents the OB fold from several telomere-binding protein beta subunits which appear to be specific to the family Oxytrichidae. Telomeres are specialized protein-DNA complexes that compose the ends of eukaryotic chromosomes. Telomeres protect chromosome termini from degradation and recombination and act together with telomerase to ensure complete genome replication. TEBP beta forms a complex with TEBP alpha and this complex is able to recognize and bind ssDNA to form a sequence-specific, telomeric nucleoprotein complex that caps the very 3' ends of chromosomes.
Links
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Statistics
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PSSM-Id: 462156
Aligned: 6 rows
Threshold Bit Score: 215.398
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2I0Q_B     23 NNEGDFSKVSSNLKKP-LKCYVKESYPHFLVTDGYFFVAPYFTKEAVNEFHAKFPNVNIVDLTDKVIVINNWSLELRRVN 101 
CDW85312   21 NLGGDFSKVSKDLKKP-LKTYVKESYPHFLVTDGYFFVQPHFTKEAVAEFHQKFPNVNIVDLHDKVIVINTWSLELRRVN 99  
CDW80594   21 NANFDFEAIPLQLKKS-MRVGVQEHIAFFWVNDGYHFLEAVFTKEAVNEFRKNWPHLKFIGLKEKILLITKWSLRIREAD 99  
CDW74302    3 SKNGEFSKIGDFKKAK-IRCYVKETYPKFLISDGSYFISGYFTKDWLKNSE--KNKIRITDLNEGLILINKWSIELAKVN 79  
EJY83063   30 SNQGDYNKLPDNLKRAkIRCQVRETYPKLLISDGSFFIAGYITKECQNKCEQK--KVKITDLKDGLILITKWNVELTLVN 107 
EJY64211   21 NSNFDFEAIPLNLRKH-MRLSVQENIATFWVNDGFHFLEAQFTKDAINEFRKSYSHIKFQSLKGGIMFISKWSLKIKECD 99  

2I0Q_B    102 SAEVFTSYANLEARLIVHSFKPNLQERLNPTR--Y--PVNLFRDDEFKTTIQHFRHTALQAAINK 162 
CDW85312  100 SAEVFTSYANLEARLVVHSFKPNLQERLNPTR--Y--PVNLFRDDEFKTIIQHFRHQALQQSIAK 160 
CDW80594  100 SRKLFTSYQNLQIQIVIEGFKPILHEKPNPKQ--HfqATNIYHDEEIQTYLRHKRHEMIRGFLSN 162 
CDW74302   80 SAEDFTSYSGIEMRLIIHDFKVNKDEDLKMSK--F--PTNLYRDDEVKSRVLEFIADQRSEKLAE 140 
EJY83063  108 SAEEFTSYSGIEMRVIIHEFRVNQEEDLKMSK--F--PTNLYRDDEVKASILHFIQAQRLQQLNN 168 
EJY64211  100 SRKVYTSYQNMQIQLVIESFKPLLHEKPVRHQlvN--AINIFHDEDVQIYIRHKRHEFIKEILNT 162
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