Conserved Protein Domain Family
GIY_YIG_domain
?
pfam19239: GIY_YIG_domain 
GIY-YIG domain-containing protein
This is a family of proteins that contain the GIY-YIG domain, predominantly found in Bacteria, Fungi and plants (i.e. in Protein EFFECTOR OF TRANSCRIPTION 1,2 and 3 from Arabidopsis) but also in viruses. This is a well characterized domain among the members of the GYI-YIG endonuclease family, which is involved in several cellular processes such as DNA repair and recombination and transfer of mobile genetic elements.
Links
?
Statistics
?
PSSM-Id: 466008
Aligned: 47 rows
Threshold Bit Score: 199.006
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
PNR55098      42 FSKWKILIGPSDWSDYATGKIGIERCQVQNLPDFNLgPGVYELGVTApswvPTlhskrPRsLRRED----VIAVYVGQAV 117 
Q9FJT6        69 FSKWRNLIRHNDWKDFNNRKERVRRYRHEDLPPQRC-TGLYELGVGVig--------qDQ-GQNFDpdnnVLGVYVGQCV 138  thale cress
RID60976      31 FSNWKVLIGSEDWEDFKKGKDGVGRYRVQNLPRRSC-PGLYELGVAVi----------DQ-ARKLDsd-dVLAAYLGQAE 97  
XP_016720447  27 FSKWKVLIGPHDWEDHSVGKEGVARYRVENLPKTAS-SGLYELAINKps--------sRDhNGKLDsd-kVLVVYLGEAD 96  
XP_016729123 549 FSKWKLLICPHDWENGKGG--AVTRYRSENLPKSSG-PGTYELAVs------------RDrHGKLEp---dLVVYVGAAE 610 
CDP03186      48 FSPWKVLIGPSDWEDHSNGKEGAERYRTQNLPNCTScTGVYELGTAV----Wrsk-srRD-AGKLDpd-fIIPVYLGKSD 120 
EYU30651      31 FSEWKILIGSMDWKEHAMGKEGAERYRTHNLPNCACsPGVYELAVAL----VLrrhs---------giiiLVPVYVGQTE 97  
TEY53226      30 FSHWKILIGAFDWEDHSMGKEGVERYRTQNLPNWTScPGVYELGVAQ----SGke------tRKLDsa-sVIPVYLGQAD 98  
XP_012848581  31 FSDWKILIGAYDWEDHSMAKQGAEKYRTQNLPNWTScPGVYELGIAS----SRphsgrGA-HRKFDsn-sVVPVYLGQAD 104 
KNA21639      37 FSKWKILIGASDWVDYEAKKEGAERYRVSNLPKVCS-PGLYEIGVAV----CLsg-sgRD----LEte-rIVVVYLGQAD 105 

PNR55098     118 NIRQRLHKYGQTGAHLEGSrsfatscqgddgsvsggsstprtwngGgdaakvaaEIGPRLFSEAFALGSSIAFRWAHTDS 197 
Q9FJT6       139 DVKSRLQDYGRRGGHLPS----------------------------------------GLYEDIFSEGYSVFYRWAP--- 175  thale cress
RID60976      98 SVRSRLQSYGRSGAHLRTVnnnnldg------------ccesppdK----------KAGLFEDIFMKHGSVVYRWAPMGS 155 
XP_016720447  97 NVRSRLQQYGRTGAHLGRNds-------------------------------gdNKGRGCFEDIFARGYSIVYRWAPMEN 145 
XP_016729123 611 NIRARLQQYGRDGTHLCRK-----------------------------------DKGCPLFD-IFARGCSIVYRWVPREN 654 
CDP03186     121 NVRNRLQQYGREGAHLENGssntkln-------------gcngslA--------QTGSGLFKDIFSEGFSIVYRWAPMKS 179 
EYU30651      98 NIRNRLQDYGRNGAHLESNg--------------------------------------lLVSDVFSRGFSIVYRWAPMKS 139 
TEY53226      99 NLRIRLQQYGRNGAHLENGcstsktv-------------dcqsvfA--------HKGLGLFTDIFSRGLPIVYRCAPMKS 157 
XP_012848581 105 NLRTRLQQYGRDGSHLESRcsnnklt-------------dcqsvsS--------NKGLGLFTGVFSRGLPIVYRCAPMKS 163 
KNA21639     106 NVRSRLQEYGRTGSHLVH--------------------------------------GFGLFKDIFSTGFPIVYRWAAMKS 147 

PNR55098     198 KVVAEQVESELL-AVFDYAWNKGINGTRRSRDIL 230 
Q9FJT6       176 --EAAATEGMLL-STFDYAWNTCSNGERRHLE-L 205  thale cress
RID60976     156 KREAEATEGMLL-STFDYAWNKGSNGERRHLDLL 188 
XP_016720447 146 KADARRTEVQLL-TTFDYAWNKGSNGVRCQDDIL 178 
XP_016729123 655 KADALRTEAQLL-GTYDYPWNKGSNGIRRHDDIL 687 
CDP03186     180 TRDADKTESDLL-GKFDYAWNKGSNGPRRHNDIL 212 
EYU30651     140 KEEAEETEKEMLiECYDYAWNKRNNGERRPDD-- 171 
TEY53226     158 KKEAEITEKQLL-DRFDYAWNKGSNVSRRQDDIY 190 
XP_012848581 164 KKDAEITEKQLL-EKFDYAWNKDSNNKRRQDDVS 196 
KNA21639     148 KSDAERTESELL-ERFDYAWNKIGNNARRPNDVL 180
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap