4D9M


Conserved Protein Domain Family
2_3_DAP_am_ly

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TIGR03528: 2_3_DAP_am_ly 
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diaminopropionate ammonia-lyase
Members of this protein family are the homodimeric, pyridoxal phosphate enzyme diaminopropionate ammonia-lyase, which adds water to remove two amino groups, leaving pyruvate.
Statistics
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PSSM-Id: 274631
Aligned: 10 rows
Threshold Bit Score: 744.619
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4D9M_A         5 SLKIDIADNKF---F-NGETSPLFSQSQAKLARQFHQKIAGYRPTPLCALDDLANLFGVKKILVKDESKRFGLNAFKMLG 80  Escherichia col...
WP_012047950   4 NIKWKSNTMKGn--A-DKASVEFLGEEEIKKARDFHQSFPQFTKTPLVNLDNLAKHLGVAGIYVKDESYRFGLNAFKVLG 80  Clostridium bot...
WP_011367266   3 NIRFIANQKARq-qT-DKVDVSFLSCAEAEVVRGFFKTFEGYEPTPLVGLKGLAAELGVSSFYLKDESKRFGLNAFKVLG 80  Desulfovibrio a...
WP_015944310   4 EIKIISFQRDKq----KASDLTFLNLEEAEKVHSFHVSFPIYQKTPLRELKNTAQALGLGTVYVKDESYRFGLNAFKVLG 79  Desulfitobacter...
WP_011188629   3 SVRIKFNENPIa-pL-KGTEVSLLSKEVAEKVRDFHQTFPSYQPTPLAKLDQLAEHLGLGSILIKDESYRFGLNAFKVLG 80  Desulfotalea ps...
WP_000544849   4 lIKYQFNTRRKk--YgTGAALSLLNGNVGHEVLAFHKKLPNYAVTPLHNLAHLSQRLGLGSIHIKDESWRFGLNAFKGLG 81  Salmonella ente...
WP_011218695   5 SLKMEIADNRH---Y-NGQLSSLFTIDEAEKARAFHQKVEGYQPTPLQSLDCLAKEIGVGKILVKDESHRFDLCAFKMLG 80  Photobacterium ...
WP_002387140   3 KIKWTANEMPK---T-EDKYLPLMSKEKIEKALAFHKSFPQYSETPLAELNHMAAYLGLNDFFVKDESYRFGLNAFKVLG 78  Enterococcus fa...
WP_000110494   5 SLKIDIADNKF---F-NGETSPLFSQSQAKLARQFHQKIAGYRPTPLCALDDLANLFGVKKILVKDESKRFGLNAFKMLG 80  Escherichia
WP_011098399   6 AIKYILNNKARgniS-EKTNTDFISDEVINKVRNFHRSFPEYEVTPLHKLDNLAKHLGVKNIFLKDESYRFRLNAFKVLG 84  Clostridium tetani
4D9M_A        81 GAYAIAQLLCEKYHLDIETLSFEHLK-NAIGEKM---TFATTTDGNHGRGVAWAAQQLGQNAVIYMPKGSAQERVDAILN 156 Escherichia col...
WP_012047950  81 GSFSMGKYLAKRLGKDISELSYEKLNsEDARKKLgdiTFITATDGNHGRGVAWTATQLNQKSIVYMPKGSSLTRLENIRK 160 Clostridium bot...
WP_011367266  81 GGYAIAKHICRRLGVPIAEMSMERLCsAEVREALgevTFVSATDGNHGRGVAWAANRMGQKSVIYMPKGSAVTRLENIRA 160 Desulfovibrio a...
WP_015944310  80 GSYAIGNYIASKLGTDIRDLPYEKMVsEEVRSKLgelTFVTATDGNHGRGVAWTANQLKQRSVVYMPKGSAPERLENIRA 159 Desulfitobacter...
WP_011188629  81 GSYAVGKILAEMLGKDISEVSCSDLSsKETSDKIgdiTFASTTDGNHGRGLAWAAKEFNKKAIIYMPKGSAPIRRDNIQA 160 Desulfotalea ps...
WP_000544849  82 GSYAVGKYLADKLQCDINSLSFAALNtPEIKEKIkdcVFVTATDGNHGRGVAWAAEQLGLKAVVYMPKGSSLIRAENIRH 161 Salmonella ente...
WP_011218695  81 GAYAIARLLCDEYQLDINVFDFDTLK-NDIKEKM---TFATATDGNHGRGVAWAANKLGQNAVVYMPKGSADERVNNIRA 156 Photobacterium ...
WP_002387140  79 GSFAMANYIAEKLKKDVSELTYDELTsDQLRSAFgqaTFFTATDGNHGRGVAWAANKLGQKSVVLMPKGSTQTRKENIEK 158 Enterococcus fa...
WP_000110494  81 GAYAIAQLLCEKYHLDIETLSFEHLK-NAIGEKM---TFATTTDGNHGRGVAWAAQQLGQNAVIYMPKGSAQERVDAILN 156 Escherichia
WP_011098399  85 GAYAIGKYLAKKLDIDISEISFEKLKsKEVKEKLgdiIFVTATDGNHGRGVAWAANRLGQKSVVYMPKGSSQIRLENIRK 164 Clostridium tetani
4D9M_A       157 LGAECIVTDMNYDDTVRLTMQHAQQ--HGWEVVQDTAWEGYTKIPTWIMQGYATLADEAVEQMREMGVT-PTHVLLQAGV 233 Escherichia col...
WP_012047950 161 EGAKASITEFNYDDAVRLAASEAKE--NGWVMVQDTAWEGYEEIPTWIMQGYGTMASEALEQLKELNVEkPTHIFVQAGV 238 Clostridium bot...
WP_011367266 161 EGAQASITDLNYDDAVRLAWKDSQE--KGWVMVQDTAWEGYEEIPGWIMQGYTTLALEALEEFERQEGEaPTHVFLQAGV 238 Desulfovibrio a...
WP_015944310 160 EGAEASITELNYDEAVRLANRKAEE--NGWIMVQDTAWQGYEDIPRWIMQGYGTLGYEVYGQLK----EkPTHIFLQAGV 233 Desulfitobacter...
WP_011188629 161 LGSDCTITELNYDDCVRMAWDKAQQ--EGWITVQDTAWDGYEDIPNTIMQGYTTLALEALEQMQAQGIErPTHVLLQAGV 238 Desulfotalea ps...
WP_000544849 162 HGAECTITDLNYDDAVRLAHRMAQT--KGWVLLQDTAWTGYEEIPTWIMQGYMTLAVEAYEQLAETNSPlPTHLILQAGV 239 Salmonella ente...
WP_011218695 157 LGAECIVTDMNYDDTVRLAIKTAEE--CGWKIVQDTAWEGYTKIPTWIMQGYTTLAAEAVDQMKIHAVAkPTHVFLQAGV 234 Photobacterium ...
WP_002387140 159 EGATVTIEEVNYDECVRMANKMAEEteNG-VMVQDTAWDGYEKIPTWIMQGYGTMALEASQQLRKFGSErPSHVFVQAGV 237 Enterococcus fa...
WP_000110494 157 LGAECIVTDMNYDDTVRLTMQHAQQ--HGWEVVQDTAWEGYTKIPTWIMQGYATLADEAVEQMREMGVT-PTHVLLQAGV 233 Escherichia
WP_011098399 165 EGAEATIIDGNYDDAVRLADKMAKK--YGWIVIQDTAWEGYEDIPTWIMQGYGTLIHEVIEQLERSGINnVTHVFLQAGV 242 Clostridium tetani
4D9M_A       234 GAMAGGVLGYLVDVYSPQNLHSIIVEPDKADCIYRSGVK--GDIVNVGGDMATIMAGLACGEPNPLGWEILRNCATQFIS 311 Escherichia col...
WP_012047950 239 GSLAGAVQGYFASVFKDECPITVIVEADEADCLYRSAIAgdGKPRAVTGDMPTIMAGLACGEANTIGWEVLKSYSSTFVS 318 Clostridium bot...
WP_011367266 239 GSFAGGVQGLLAQRYGERRPVTAVVEPELADCIFRSAAAadGNPHFVTGDMPTVMAGLACGEPNTVGWSILRDYSDGYIS 318 Desulfovibrio a...
WP_015944310 234 GSMAGAVTGFFASLYGEERPIIAIVEPNKADCLYLTAQAddGERHFVTGEMNTIMAGLACGEPCSIAWEVLKDYADHFIS 313 Desulfitobacter...
WP_011188629 239 GCFAGAMIGFFMSAFGKDCPKFIIVEPDAANCFYVSACAndGKPHTVEGDLLTLMAGLACGEPNKTSWEMLRDYPVAYAS 318 Desulfotalea ps...
WP_000544849 240 GSFAGSVMGYFVEKMQENIPNIIVVEPHQANCLYQSAVMddGQPHCVTGDMATIMAGLACGEPNIISWPIIRDNTSCFIS 319 Salmonella ente...
WP_011218695 235 GALAGGVLGYLCDLYGAENLHSVIIEPDQADCIYRSGISadGGMVNVGGDMATIMVGLACGEPNPLGWPVLRDCATQFVS 314 Photobacterium ...
WP_002387140 238 GSLAGAVIGYFANAFPENPPIMVVVEAQAADCLYQSAIKkdGEIRFVDGDLQTIMAGLACGEPNTISFDILKNHTSFFVS 317 Enterococcus fa...
WP_000110494 234 GAMAGGVLGYLVDVYSPQNLHSIIVEPDKADCIYRSGVK--GDIVNVGGDMATIMAGLACGEPNPLGWEILRNCATQFIS 311 Escherichia
WP_011098399 243 GSFASAIQGYLASKFGEERPITVIVEPDDAACIYKSAKVndGKPHIVTGDMPTIMAGLACGEPNSIGWEILRDYSDGYLS 322 Clostridium tetani
4D9M_A       312 CQDSVAALGMRVLGNPYGN-DPRIISGESGAVGLGVLAAVHYHPQRQSLMEKLALNKDAVVLVISTEGDTDVKHYREVVW 390 Escherichia col...
WP_012047950 319 CPDWVSANGMRMLGNPIKE-DKKIISGESGAVTAGLLKAIMTEDDMKELREQLNLDENSRILLFSTEGDTDPDKYRKIVW 397 Clostridium bot...
WP_011367266 319 CPDWVAANGMRILASPRPG-DARVISGESGAVTTGIVECLMRMPDMAPVREALELDGDSRVLVISTEGDTDPVMYRKIVW 397 Desulfovibrio a...
WP_015944310 314 CPDYVAAKGMRILGNPVQG-DERVISGESGAAPFGCVAEIMTNPLYKEIKDQLQLNENSRVLFFSTEGDTDQENYQAIVW 392 Desulfitobacter...
WP_011188629 319 CSDDIAATGMRVLGAPIKG-DPQVTSGESGAATTGFLHWVMTSEEGKEAREKLGLDLNAQVLCISTEGDTSPELYRDVLW 397 Desulfotalea ps...
WP_000544849 320 ADDCLAAKGMRISAAPRPGtDTPFISGESGAIGVGLLYELMNNMHYQDLANRLQLDASAHVLLISTEGDTSPDIYEDIVW 399 Salmonella ente...
WP_011218695 315 CQDSVAALGMRVLGNPLGD-DPRVISGESGAVGAGLLVAAYYHPDREALMAKMGLNKDSVVLLINTEGDTDPVHYREVVW 393 Photobacterium ...
WP_002387140 318 APDWVSEKGMRMLGAPLKG-DPQVVSGESGAVAMGLVATVMQDPDYQELHEALQLDETSNVLMFSTEGDTDPDNYKKILW 396 Enterococcus fa...
WP_000110494 312 CQDSVAALGMRVLGNPYGN-DPRIISGESGAVGLGVLAAVHYHPQRQSLMEKLALNKDAVVLVISTEGDTDVKHYREVVW 390 Escherichia
WP_011098399 323 CPDYVSARGMRILASPLRG-DNQIISGESGAVGVGVISLLMERDYYKELREKLDLNKNSRVLLISTEGDTDPGKYRNIVW 401 Clostridium tetani
4D9M_A       391 EG 392 Escherichia coli K-12
WP_012047950 398 NG 399 Clostridium botulinum
WP_011367266 398 QG 399 Desulfovibrio alaskensis
WP_015944310 393 DG 394 Desulfitobacterium hafniense
WP_011188629 398 HG 399 Desulfotalea psychrophila
WP_000544849 400 NG 401 Salmonella enterica
WP_011218695 394 QG 395 Photobacterium profundum
WP_002387140 397 R- 397 Enterococcus faecalis
WP_000110494 391 EG 392 Escherichia
WP_011098399 402 DG 403 Clostridium tetani
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