3N2B,4XG1,2P3E,2QGH


Conserved Protein Domain Family
LysA

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COG0019: LysA 
Diaminopimelate decarboxylase [Amino acid transport and metabolism]
Diaminopimelate decarboxylase is part of the Pathway/BioSystem: Lysine biosynthesis
Statistics
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PSSM-Id: 439790
Aligned: 721 rows
Threshold Bit Score: 160.7
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3N2B_A        25 MDY---FnyQEDGQLWAEQVPLADLANQYGTPLYVYSRATLERHWHAFDKSVgd-yPHLICYAVKANSNLGVLNTLARLG 100
NP_711228      1 MQSi-------EKLKFLTESQVRSIAGQFGTPVFVYSRERIEKSCEVA-LAFpnayGLTVRYAMKANPNRTVLEIMKRKG 72 
WP_013176656   1 MDPg------R-------AALLHRIAERYSTPTYVYDLDAIGDRVARLRAALp---tAELLYAVKANPCGAVLRHLAAAG 64 
WP_011735869   1 MTQn------HFGPTRLDAALVPLIAQKWGTPVYLHDRAFIEQSCDQLLNMPna-fGLHVRYAMKANSDRTVLRVVTGKG 73 
WP_012909112   1 MPAtptF--S-TIRHEIAGVSVADIARDYGTPTYVYDAAIIEERIDDLAKF------DVIRYAQKACSNIAILDLMRKKG 71 
WP_014437684   1 MPPa--L--AESSTL---PYSPVEVASRFGTPTYVYDAATLRARARSLTGR-----GATIRYAQKANNNTAVLALLRAEG 68 
WP_013043549   1 MTDf-------TKPRFLQYTTARQIADQFGSPVYVYDMATLKANAADV-LAFpnayGLTARYAMKASPNAAILRIFNEAG 72 
WP_012388421   1 MTSi-------EKLKFLKEDQVRTLAKEFGTPLFVYSEKEIEQKCDDT-LAFpnafGLQVRYAMKANPNSNILQIMKKKG 72 
WP_022771089   1 MTQe--A--T-LGAHLFSPAALAALARTYKTPLWVYDAATIERQIAALRAF------DVVRYAQKANSNLHVLRLVRRCG 69 
WP_095415944   1 MAE---T--N-LIRTTIGGVPVVELAQEFGTPLYVYDAAVIRKRFAELAVF------DVVRYAQKACSNLAILALVRQLG 68 
3N2B_A       101 SGFDIVSVGELERVLAAGGDP------SKVVFSGVGK----TEAEMKRALQLKIKCFNVESEPELQRLNKVAGElgvKAP 170
NP_711228     73 IQIDASSEYEVLRAIHYGFKP------EQIMLTSQEL-----AKGLKELVEKGV-VFNACSLRQLETFGNLFp----GKE 136
WP_013176656  65 LGAEVISVGELARARRAGFPE------GRILLGGPRQ----DPPLVAAAW--GVGWVSLDNPSQWRGWQRFAARe-gAPR 131
WP_011735869  74 LDLDCSSVDEAARAHSAGIPY------DRMMLTTQEVplgqEREELEGMIRNGL-KYNVCSLTQYRLIADFAKQag--iD 144
WP_012909112  72 VVVDAVSTGEIHRAMAAGYKPgs--knHEIVYTADIF----DRDALATVVKLDI-PVNCGSPDMLDQLGAVKp----GAH 140
WP_014437684  69 VVVDAVTAGEIHRALAAGHEP------ADVVYTADVF----DRDAVEALHRHGC-PVNAGSPNMLAQLADAGl---eHLP 134
WP_013043549  73 LHIDASSGYEVRRAIAAGYTP------EKISLSTQEL-----PTDFAELYELGI-EINACSLSQLERFGQAFp----GRS 136
WP_012388421  73 ILIDASSEHEVVRALHFGFSP------ESIMLTSQEF-----PKAFVELIGKGV-KFNACSLRQLELFGQHFp----GKS 136
WP_022771089  70 AWVDAVSLGEIERALAAGFVPrspeghREIVLTSDVI----DAATLSRCEREGI-AVNCGSIDMIEALARVRf----EHP 140
WP_095415944  69 ALVDAVSAGEIHRALAAGYPPag--dpPPIMYTADIF----DRDALDLVVEHHI-HVNCGSRDMIEQLGERVp----GRE 137
3N2B_A       171 ISLRINPDVDAKTHPY-ISTGLRDNKFGITFDRAAQVYRLAHSlPN-LDVHGIDCHIGSQLTALAPFIDATDRLLALIDS 248
NP_711228    137 VSVRFNPGLGSGQTKK-TDVGGKTSSFGIWYEDINQVKEIASK-FD-LKIFKVHTHIGSGSD-PEVWKVVAQVSLDIAAQ 212
WP_013176656 132 FLLRLNPGLDPRTHEH-LATGAARSKFGMPFGELAALGA---A-LG-EHLAGFHVHIGSQITELGAYEPVFAQLGALLTR 205
WP_011735869 145 LSIRVHPGASGGGESQtRDTGSEYSCFGVHLNDIPTVVEMARD-KG-LRFTQVHVHIGSGGD-PEKWRENIDRELGFVRS 221
WP_012909112 141 VTLRINPGFGHGHSQK-TNTGGEQSKHGIWHEQLTDCLQKADR-HG-LMISGIHMHIGSGTD-LEHLSQVCSAMERVVl- 215
WP_014437684 135 VTLRLNPGFGHGHSRK-VNTGGTSSKHGIWHEQLEAVLTQATS-LGlSRVRGLHMHIGSGSD-FAHLHHVCDAMVAAAEA 211
WP_013043549 137 IGVRFNPGAGSGGNNR-TNVGGPASSFGIWHEWIDQVQEIVAR-YD-LKVIRIHTHIGSGSD-PKVWQKISSMSLELVRQ 212
WP_012388421 137 VSIRFNPGLGSGHTKK-TDVGGVTSSFGIWHEKLEEVKAIVNK-YN-LVVEKVHTHIGSGSD-PEVWKAVAKYTLEYAES 212
WP_022771089 141 VWLRINPGFGHGHSHK-TNTGGENSKHGIWHTDLPRACDMLLS-SG-LALWGLHMHIGSGVD-YAHLQRVSAAMTEAARI 216
WP_095415944 138 ITLRVNPGFGHGHSRK-TNTGGELSKHGIWHEQLHEALFEAEH-HG-LSVVGLHMHIGSGSD-FEHLAQVCRAMEKAAv- 212
3N2B_A       249 LK-AEGIHIRHLDVGGGLGVV-YRD--ELPPQPSEYAKALLDRLERH-----RDLELIFEPGRAIAANAGVLVTKVEFLK 319
NP_711228    213 FS-----ECKILNLGGGFKVG-RMEd-EKTTDFQKIGPPVVELFQEFakkhgTELRLEIEPGSFLMVNNGSILTTVDDVV 285
WP_013176656 206 FPh-----ADTLDLGGGFAVPgF--------ALPEFSARVRAFLAQVp-----FRRLLLEPGRFLVAESGVLLTRVLHVK 267
WP_011735869 222 YFp----DAGTVSFGGGLKVA-RMPg-EKQADINELGTYAAARLKEFkeqtgRALRMEIEPGTFVVANSGYIITRVMDKK 295
WP_012909112 216 ---EVGRSITTISAGGGLPIP-YNDk-QTYVDLDQYFELWDASRKRLeaalgHKISLEIEPGRYLVAESGYLVSEIRAIK 290
WP_014437684 212 WKaAGGHELEVISAGGGLPIP-YRKgeDEPLDLDRFFEAWTEARDRVcaivgREVELEVEPGRYLAAEAGSLVAEVRGTK 290
WP_013043549 213 FP-----DVVSLNLGGGYKVA-RMAd-EVSTDLQQCGEPVADKFREFaaetgREIRLEIEPGTYLLANACSVLSMVQDKV 285
WP_012388421 213 FP-----SVTVVSLGGGYKVG-RMEd-EKSTNLQTIGAPVKIQFEEFakkhgRKLILEIEPGTYLIALCGALLTTVDDKV 285
WP_022771089 217 Vi-GKGLRIKAISAGGGLSIP-YCNh-EVAVDVQHYHSLWNTARNRLvsllgQPITLEIEPGRFLVAQAGVLVAQVLATK 293
WP_095415944 213 ---EAGRNLRWISAGGGLPIP-YREg-DARIDIQRYFDLWDATRKRLedrfgHRVRLEVEPGRYIVAEAGFLITEIRAVK 287
3N2B_A       320 Ht----EHKNFAIIDAAMNDLIRPALYQAWQDIIPL-RPR--------Q---G-EAQTYDLVGPVCETSDFLGKD----- 377
NP_711228    286 Stg--pGGYTFVKLDAGMDVNTRPSLYAAKHPLVVVsKEG--------Vh-sG-KTADYVYVGHCCESGDLFTQAeggg- 352
WP_013176656 268 Eg-----pVRHVIADAGMADLLRPALYGAQHPVRVLgAAD------------G-ASGSADLDGPLCENADRLARG----- 324
WP_011735869 296 Lt----nEMNFLLVDGGMELLSRPLLYGSEHPISIVgQDGtlrsseydSysvG-TATPYGIVGRCCESGDSVRLDnegt- 369
WP_012909112 291 Qm----gNNTFYLLDAGFNNLARPILYGSYHPMSIVpLDA--------Ge--R-ADRDVVVGGPLCESGDIFTQEeggy- 354
WP_014437684 291 TqgegdDAVDYLLIDAGFNDLLRPAMYGAYHHLEVFaADG--------Re-lT-RERDYVVAGPLCESCDVFTQGdegv- 359
WP_013043549 286 Stg--rEGYEFLKLNTGMTEVLRPSIYGAQHPIFILkEAT--------P---T-ETCDYMIAGHCCESGDILTPAsgdpe 351
WP_012388421 286 Dtg--kHGFQFLKLDTGMDSNTRPSLYGARHPLITVkKDG--------Gi-pS-SHKEYVVVGHCCESGDVFTQKegge- 352
WP_022771089 294 Rm----gNKFYVLVDAGFNDLVRPCMYGSHHEISIVrPDG--------Tf-aTgALHDTVVAGPLCESGDVFTQDahgk- 359
WP_095415944 288 Eq----aQNTFYLVDAGFNNLVRPAMYGAYHPLRLApRDP--------Sl-pR-LFQEVIVGGPLCESGDIFTQEeggi- 352
3N2B_A       378 ----RDL-VLQEGDLLAVRSSGAYGFTMSS-NYNTRPRVAEVMV-D-GNKTYLVRQREELSSLWALES-V 438
NP_711228    353 -pitRITgEAKLGDYVVMEGAGAYCSSMSTkNYNSFPETAEVLV-DsDGSFQLIRRRQNWEQIFQNEV-T 419
WP_013176656 325 ----VALpALTPGTLLAVEQAGAYGFAMAS-NYASSLRPAEVVV-A-GGEVRLARRRETPDDLVQLEL-- 385
WP_011735869 370 -ivpVQVaEAEIGDYVVIGGTGAYSESMSPeNYNSHRKAPAVMKmK-DAELVLIRKRQVREQLVQNELdV 437
WP_012909112 355 -vckRSLpSARIGEYLVLERAGAYGFVMAS-NYNSKPLAAEVLI-K-NGTAHLVRERQTPADLIRGER-L 419
WP_014437684 360 -vqsRRLpVPEPGDLLVIHDAGAYGAAMAS-RYNGRRLTAEAMV-I-DGELHEIRAREPIDEQLRYEH-I 424
WP_013043549 352 llatRTLpVTEIGDLCVIDGSGAYCSAMSTkNYNSYPEAAEVML-DeANRPHLIRKRQDPQALWANELpm 420
WP_012388421 353 -pitRLMgEAEIGDYVVMEAIGAYCSSMSTkNYNSFPETAEVLL-RkNGETKLIRKKEPVMEIFRNEI-L 419
WP_022771089 360 -lleRPLpIVEVGDWLVLHDTGAYGASMSS-NYNTRPLAAEVLI-E-GGHPRLIRRRQTVQELLALEA-T 424
WP_095415944 353 -vtkRLLpQAAVGDYIVIECAGAYGFVMGS-NYNSKPYPPEVLV-D-NGDVKLIRRRQTYTDLFEDEM-I 417
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