5Y31,5Y31,5Y31,5Y31


Conserved Protein Domain Family
EPTP

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pfam03736: EPTP 
EPTP domain
Mutations in the LGI/Epitempin gene can result in a special form of epilepsy, autosomal dominant lateral temporal epilepsy. The Epitempin protein contains a large repeat in its C terminal section. The architecture and structural features of this repeat make it a likely member 7-bladed beta-propeller fold.
Statistics
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PSSM-Id: 461033
Aligned: 195 rows
Threshold Bit Score: 32.0553
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5Y31_B       490 KFVKFQELNVQAPRSFTHVSINKRNFLFASSFKGNTQIYKH 530
XP_006629880 288 NFRSHDNITGQSIVECKCVLIEDQIFIIVAQLFGGSHIYKY 328
NP_001034731 265 KFRPFDDITGRSAVGCRSVLINEQAFVIVLQLFDGSLVYKY 305
XP_010793541 259 NFRTYDNITGQSIVGCKSVVIQDQVFVIVAQLFGGSHIYKF 299
CAG12556     262 VFRGFRNITSRSAVYCKPALVDGGLHMIVAQLFGGSHIYRW 302
AAH42542      40 QLRDYDRIPAPSAVHCKPMVVDSQLYVVVAQLFGGSYIYHW 80  human
XP_015197428 325 VFRKFYNITSRSAVYCKPVVIENTLYMVVAQLFGGSHIFKW 365
XP_005995299 213 IFRKFENLSAQSAIYCKPLVVDDQLFVVVGQLFGGSHIYRW 253
TNN62302     258 NFRKFDNITGKSVVGCKSVLIDDHILIIVTQLFGGSHIYKF 298 Tanaka's snailfish
XP_005997930 242 NFRSYDNITGQSIVGCKPILVEGQVFVVVAQLFGGSHIYKY 282
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