Conserved Protein Domain Family
PLN02881

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PLN02881: PLN02881 
tetrahydrofolylpolyglutamate synthase
Statistics
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PSSM-Id: 215476
Aligned: 23 rows
Threshold Bit Score: 748.796
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
224086916  13 VAIIDYVQDVPLSTSYEVAMEALSSLIRQKKRGDRKGIGgk----yGKLDRMRIYLKILDLEEHMAGLKIIHVAGTKGKG 88 
115482806  89 MASVAQPGVAAGSAEYEEVLGCISSLITQKVRADTGNRG-------NQWELMAKYLQILELEEPIARLKVVHVAGTKGKG 161
79396625   68 MGSKEDKADNPALSSYDDAMEALSTLISRRNRGDRTPTKgn----rDKLEQVVTYLKILDLEDKIKELKVIHVAGTKGKG 143
115450241  44 AAAAAQAGGAVAAAEYEDVMGRLSSLITQKVRAHSGNRG-------NQWDLMAHYLQILELEEPIARMKVIHVAGTKGKG 116
168046592   1 MADVGVSVAPAINRTYEDAVIAMNSLITRKSNASRPDPDtfelnwrNQFQSLFKCLQVLELEEPLSRLSVIHVAGTKGKG 80 
168048560   1 ------------------------------------------------------WFQILEMKEPLARLSVIHVAGTKGKG 26 
145350738   1 --------MRDDDRTYDAAVRELAKTITGKKRADPGAVTw-----eAQFAQLETYVSRLDLRGRVDALDVVHVAGTKGKG 67 
224137770   8 VAIIDYLQDVPLSDSYEAALEALSSLIRQQKRGDQKTIGgk----yGKLDRMRMYLKILDLEERVAGLKIIHVAGTKGKG 83 
242034043  77 MAGVAHAGLATGSTEYEEVLGCLSSLITQKVRADTGNRG-------NQWELMAKYVQILELEESIAQLKVVHVAGTKGKG 149
225441349   5 KSTIECSEELPLSSSYEMAMEALSSLITSQKRGGRSSVSgk----yGKLDRMSMYLKILGLEEKIAGLKIIHVAGTKGKG 80 
224086916  89 STCTFCEAMLRESGFRTGLFTSPHLIDVRERFRINGVDISEDKFLSYFWNCWNRLK--EHETEDLPMPPLFQFLTVLAFK 166
115482806 162 STCTFAESILRSCGFRTGLFTSPHLMDVRERFRLNGLDISEEKFIRYFWWCWNKLK--DKTGGDIPMPAYFRFLALLAFK 239
79396625  144 STCVFSEAILRNCGFRTGMFTSPHLIDVRERFRIDGLDISEEKFLQYFWECWKLLK--EKAVDGLTMPPLFQFLTVLAFK 221
115450241 117 STCTFTEAILRSCGFSTGLFTSPHLMDVRERFRLNGVDISEEKFLKYFWWCWNKLK--EKTDDDIPMPTYFRFLALLAFK 194
168046592  81 STCAFTERMLRESGFRTGLFTSPHLLDVRERFRLNGEEISQDRFLYHFWWCWDRLKavNE-----KLPGFFRFCTLLSLR 155
168048560  27 STCAFTERMLRESGFRTGLFTSPHLLDVRERFRFNGEMISKDRFLYHFWWCWDRLQvlNELANNADLPGFFRFCTLLGLR 106
145350738  68 STCAMVEGMLRASGTRVGTFTSPHLMDVRERFRIDGAMVDEETFAREFWWTRDAIA--AR-CGDLGMPAYFRFLTLLGLR 144
224137770  84 STCTFCEAILRESGFRTGLFTSPHLIDVRERFRINGVDISEVKFLLYFWNCWNQLK--EHETEDLPMPPLFQFLTVLAFK 161
242034043 150 STCTFAESILRSCGFRTGLFTSPHLMDVRERFRLDGLDISEEKFIRYFWWCWNKLK--DRIGDDVPMPAYFRFLALLAFK 227
225441349  81 STCTFCEAILRECGFRTGLFISPHLIDVRERLRIDGLDISEEKFLMHFWDCWNRLK--EKVTNDLPMPPLFQFLSVLAFK 158
224086916 167 IFVCEQVDVSIIEVGLGGRNDSTNVIEEPVVCGITSLGMDHTEALGNTIGQIASHKAGIFKHQIPAFTVPQVSEAMDVLQ 246
115482806 240 IFSDEQ-------------------VKAPVVCGISSLGYDHMEILGNTLGEIAGEKAGILKKGVPAYTVPQPEEAMSVLK 300
79396625  222 IFVCEKVDVAVIEVGLGGKLDSTNVIQKPVVCGIASLGMDHMDILGNTLADIAFHKAGIFKPQIPAFTVPQLSEAMDVLQ 301
115450241 195 IFSAEQVDVAVLEVGLGGKFDATNVVEAPVVCGIASLGYDHMEILGNTLGEIAGEKAGIFKKGVPAYTAPQPEEAMIALK 274
168046592 156 MFTEEKVDVAILEVGLGGRLDATNVVKSPVTCGIASLGFDHMELLGDTLEKIAWEKAGIFKAGVPAFTAPQLDEAMGSLL 235
168048560 107 MFTAEKVDVAILEVGLGGRLDATNIVESPVVCGIASLGYDHMELLGNTLAEIAWEKAGIFKAGVPAFTAPQPEEAMGSLQ 186
145350738 145 IFSSAGVEACVLEVGLGGRLDATNVVRAPAACGITSLGMDHVDILGDTLGKIATEKAGIMKPGVRTFTAPQKPEAMVALE 224
224137770 162 VFVCEQVDVSIIEVGLGGRNDSTNVIEKPVVCGITSLGMDHTETLGNTIGQIASHKAGVFKHQIPAFTVLQVSEAMDVLQ 241
242034043 228 IFSDEQVDVAVLEVGLGGKYDATNVVRAPVVCGVSSLGYDHMEILGSTLGEIAGEKAGILKKGVSAYTVPQPEEAMSVLV 307
225441349 159 IFTCEEVDVAIIEVGLGGKRDSTNVIKEPVVCGITSLGMDHTETLGDTLGKIASHKAGIFKPQIPAFTVPQLSEAMDVLQ 238
224086916 247 ENAQELTVPLKVVEPLDSN-ELNGLKLSLSGNHQLSNAGLAVSLCKCWLQRTGn--wEKLFQIDNKEANLPEAFLRGLSK 323
115482806 301 HRASELGVPLQVVQPLDPQ-QLDDQPLGLHGEHQYMNAGLAVALVNTWLQRQG----HFNILHKKHSVTLPDQFIEGLSS 375
79396625  302 KTANNLEVPLEVVAPLEPK-KLDGVTLGLSGDHQLVNAGLAVSLSRCWLQRTGn--wKKIFPNESKETEIPVAFCRGLAT 378
115450241 275 QRASELGVSLQVAHPLEPH-QLKDQHLGLRGEHQYVNAGLAVALASTWLEKQG----HVERIPLNRTDPLPDQFISGLSN 349
168046592 236 KRAKELGITLEVAPPLENY-NLHGLQLGLGGQHQRVNAALAVALCKQWVMTRPpselHDGLKKVLSNGRLPDSFVRGLQL 314
168048560 187 KRARELGITLKVAPALEDY-GLSDLQLGLGGEHQRINAALA----------------------ILGGGILPDSFVKGLQL 243
145350738 225 RRAAEVGSPLVVARDLDSYeGGSEIEVGLAGPHQRVNAAVAVELVREWANATNqp-wAEEMEASFARNELPESFRVGLEK 303
224137770 242 ENARELMVPLKVVEPLDSK-ALNGLKLSLSGDHQFSNAGLAVSLCKSWLQRTGn--wEKLFQKDNREANLPEAFLRGLST 318
242034043 308 QRASELGVSLQVVQPLDPQ-KLEDQPLGLHGEHQYMNAGLAVALANTWLEREG----HLNRIHVKHSGTLPDQFIKGLSS 382
225441349 239 QRAHELEVPLEVAAPLDHK-NLKGLKLSLSGDHQFINAGLAVSLCKCWLQSTGn--wEKLLKNANQEDDLLEAFLRGLST 315
224086916 324 AHIAGRAQIVPDlsstsssciSSEVAEASGDLIFYLDGAHSPESMEVCAEWFSSAVKENN-----LSSSLVSFSSHDIEs 398
115482806 376 ACLQGRAQIVPD---------PEVLSKDSSSLIFYLDGAHSPESMEICAKWFSCVTRKDE-----QQPGPLDQLHIG--- 438
79396625  379 ARLHGRAQVVHDvvsd-pqdsSDSMETPCGDLIFYLDGAHSPESMEACGRWFSSAVRGDKs---lSTAVNGYMRHGEYG- 453
115450241 350 ASLQGRAQIITDsq------vNSGEEDKDCSLVFYLDGAHSPESMEICARWFSHVTKEDR-----TVPSSMVQSQSC--- 415
168046592 315 TKWAGRAEVIHD---------------PSGCLSFYLDGAHSPESMEACANWFCSSIRLEEnlktpEQNGSHYLSNRGAD- 378
168048560 244 TKWAGRAEVIHD---------------PSGRLSFYIDGAHSPESMEACANWFCSRIKHEE-------------------- 288
145350738 304 TTWPGRSQVMHD--------------PDVMNLTFYLDGAHTIESMRHSAEWFTSTARAVT-------------------- 349
224137770 319 AHISGRAQIVHDssss-sshvSSEVAETSGDLIFYLDGAHSPESIEACAKWFSVAVKGNN-----QSPPLVLSSSHNIEn 392
242034043 383 ACLQGRAQIVPDpq-----vnSENNKDRDSSLVFYLDGAHSPESMEMCARWFAHITNNDG-----TQTCSLEQPHTD--- 449
225441349 316 ARLSGRAQTVYDtplk-synlSEATENSFGDLIFYLDGAHSPESMDVCARWFSNAVKERR-----NSPSSSFVKVGNMVn 389
224086916 399 inkvpgngymqheKFNIQEINKISKKILLFNCMDVRDPQILLPRLVSTCASSGTFF-SKAIFVPSISTYNKVTSGtsvVP 477
115482806 439 ---------------------TNSRKILLFNCMSVRDPQRLLPCLLATCAQNGLQF-DHALFVPNQSQYNKLGSHa-sPP 495
79396625  454 -----------------TDLNRVSKQILLFNCMEVRDPQVLLPKLVTTCASSGTHF-SRALFVPSMSTYNKVISGasaIP 515
115450241 416 ---------------------GNSQKILLFNCMSVRDPMRLLPHLLDTSTQNGVHF-EMALFVPNQSQYNKLGTNs-sAP 472
168046592 379 -------------EQDWNSRGTMVRRVLLFNCMPKRDPVALLQPVVNLCSRNGFPL-HAAFFVPPYSSYTSVDA----PQ 440
168048560 289 -------------TTEVVHCVYVNLQVLLFNCMPKRDPVLLLQPVINLCSKNGFPI-HAAFFVPPYSSYTSVGT----SH 350
145350738 350 ----------------------AEHNIMLFNCMDDRKPEDLLEPVADVFHTTSNVQlERAIFSPPDSTTSG-------LD 400
224137770 393 inivwknghvqheKCNIQEFNKISKKILLFNCMEVRDPQILLPRLVSTCASSGTFF-SKAIFVPSISTYNKVTSGtsvIP 471
242034043 450 ---------------------RDSRKFLLFNCMTVRDPQRLLPHLLDTCAQNGLHF-EQALFVPNQSQYNKLGSLa-sPP 506
225441349 390 gyi-------hhkKEDTEESNKISKQILLFNCMEVRDPHILLPQLVRTCASSGTHF-SKALFVPSISTYNKVTSGdsiVP 461
224086916 478 SDISSKDLSWQFSLQRLWEKIVHGIDTdsllekstkmdgae---tlprrqflyedasnCSPTDGYLACSAVIPSLPLTIK 554
115482806 496 SERVQIDLSWQLSLQRVWEGLLHSNKG--------------------------------LNGSNSSTASSVFESLPLAIK 543
79396625  516 SDTRRKDLTWQFRLQRLWEKSIQGTDAgldhtlkpdgital----pphdflcgdapqcGGPAGTPVTSSAVMPSLPLTIN 591
115450241 473 AEPEQIDLSWQLSLQRVWQKLLHGDKG--------------------------------MNNTNSSENSLVFESLPLAME 520
168046592 441 VSTTAVDTTWQQTLQRHWESVWQNKISgessdaspaqeeihvsqiellsdlrnapegqPQHGSCLGPSSAVLRSLPAAVD 520
168048560 351 QAPTVTDATWQHTLQRHWESLWRDKLT-------------------------------GIHGNMLGPSSAVLRSLPSALD 399
145350738 401 KCGDAKATSWQDRCARTWDDIIVKRAN-------------------------------VLAEKAQDTRGVVVSSIHQALS 449
224137770 472 SDISSKDLSWQFSLQRLWERIVHGIDTdllekstkmdaaet----sphreflyedasnCSPSNGYLACSAVIPSLPLTIK 547
242034043 507 SEREQIDLSWQLSLQKVWENLPNGNKG--------------------------------LNDANSGRTSSVFESLPLAIK 554
225441349 462 LDLPARDLSWQFNLQRIWEKIIHNKDVvvdesfkmdspri-----lppfeflyengssGSPSSKCLSSSAVMPSLPLTIR 536
224086916 555 WLRHCVRENPSLRLQVLVTGSLHLVGDVLKLIRR 588
115482806 544 WLRETAQQNQSTSYQVLVTGSLHLVGDVLRLLKE 577
79396625  592 WLRDCVRRNPSLKLEVLVTGSLHLVGDVLRLLKR 625
115450241 521 WLRTNARQNRSTSFQVLVTGSLHLVGDVLRLVKK 554
168046592 521 FFRNCSIHHPYLRIQVLVTGSLYLVGDVLRLLKH 554
168048560 400 HFRNCLTHHPQLRVQVLVTGSLYLVGDLLKLLKR 433
145350738 450 LIRHRAREVAPARVNVLVTGSLYLVGDVLRHLKK 483
224137770 548 WLRDCVRENPSLRLQVLVTGSLHLVGDVLKVIRR 581
242034043 555 WLRETAQQNQSIRFQVLVAGSLHLVGDVIRLLKK 588
225441349 537 WLRDCVKENPSLRLQVLVTGSLHLVGDVLKLLRR 570
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