Conserved Protein Domain Family
hyd_TM1266

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TIGR03959: hyd_TM1266 
putative iron-only hydrogenase system regulator
Members of this protein family occur as part of a system for producing iron-only hydrogenases, dependent on radical SAM proteins HydE and HydG and GTPase HydF. One member of this family, TM_1266 from Thermotoga maritima, has a known crystal structure. The small size, about 80 residues, and a distant relationship to the nickel regulator NikR of the CopG transcriptional regulator family suggest a role as a transcription factor. [Regulatory functions, DNA interactions]
Statistics
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PSSM-Id: 274882
Aligned: 50 rows
Threshold Bit Score: 91.784
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EEG54007      4 RIAVIGIIVENRESVE-A-VNTILHQYGQYIIGRMGLPYEKKKMNIISIVVDAPQDAISALSGKLGRLPGITSKALYS 79  [Clostridium aspar...
EDQ95201     11 RVAVISAILEEPDICQkQ-FNDIISKYKHIIKGRMGIPCEVENISVISIVVVGELDLINSLTGKLGKIPSVLVKTSIS 87  Intestinibacter ba...
EDS72174      2 RIAVVSMVLDDPTSVQkE-VNEVIGSYKDIIKGRMGVPLPDEDVSIISIAVVGEVDMINAFTGRLGKIPNVQVKTSFS 78  Anaerofustis sterc...
EDP15247      4 RLAVISCIISNPDSVA-T-VNEKFHLQSGLIIARLGVPCRDYGVSVISVVLHGTQNQISSFAGDLGKVDGVKVKSIQV 79  [Clostridium] bolt...
WP_012158790  4 RIGVVGIVVEDIEISP-K-VNAILHDYADIIVGRMGIPYRDKGISIISIIVDGSMDTISAMTGKLGKLTGISVKTALT 79  Alkaliphilus oreml...
WP_012003779  3 RFYIVNIIVEDRQNAY-RqVNEFLHNFAEVIRLRVGYPVPDENIAIILLVVKASNDLIGSMSGKLGQIKGVKVKTMPI 79  Thermotoga
WP_012580431  3 RFYTVDIIVTNRDDAY-EnVNQILHDFSRYIKLRVGYPIESENMAVIFVLFRATNDILGSFTGKLGQIKNVKVKSIPI 79  Thermosipho africanus
WP_012101193  3 KIAVISAILEDPKNCQqK-FNEIIADFKGIVKGRMGIPFEEEGVSVISITVTGTLDEINSLTGKLGNLENVYVKTSIS 79  Clostridium botulinum
WP_011993426  7 RYYTVDIIVIDRNNAYsK-VNELLHQYSDIIKLRVGYPVPDENIAIVFLIVKATNDIVGAFTGKIGNIKGVKVKSIav 83  Fervidobacterium n...
WP_012057803  3 nFYSINIVVGKRSESYdK-VNEILHNFSKYIKLRVGYPIEEEDSAVIFILFKGNNDILGSFTGKLGQIKYVKVKSMLI 79  Thermosipho melane...
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