2XRI_A         32 YFLVLDFEATC-------DKPQ---------IHpqEIIEFPILKLNGRtmE-----------IESTFHMYVQpvvHPQLT 84   human
Q12090        242 NVLSLDCEMAF-------TSLG----------Y--EMIRLTIVDFFTG---------------KTLFDHVIQp--IGDIV 285  Saccharomyces...
O16312        220 PMFSVDCEMCE-------TDVAn---------R--ELTRISIVDEFE----------------NTILDTLVKp--EGRIT 263  Caenorhabditi...
O76875        347 AVYALDCEMSY-------TGRG----------L--DVTKVSLVALNG----------------QLVYEHFVRp--VCDII 389  fruit fly
EDN61859      224 hIFALDCEM-C-------LSEQ---------GL--VLTRISLVNFDN----------------EVIYEELVKp--DVPIV 266  Saccharomyces...
XP_003318228   47 gIYALDCEMCY-------TTHG----------L--ELTRVTVVDADMR----------------VVYDTFVKp--DNEIV 89   chimpanzee
NP_741135     270 RVYALDCEMVY-------TIAG---------PA---LARLTMVDMQRN--R--------------VLDVFVKp--PTDVL 312  nematode
NP_593053     885 MLVGIDSEFVAlqqeeteVRSDgtkstikpsKL--SLARVSVLRGEGP--Nk----------GLPFIDDYVAt--DDKVT 948  Schizosacchar...
NP_011421     905 TLVAIDAEFVSlqselceIDHQgirsiirpkRT--ALARISIIRGEEG--El---------yGVPFVDDYVVn--TNHIE 969  Saccharomyces...
NP_498519     893 SLAVQSLEELPkek-elvGLDAefi----kiKT--DLLEFDGKTVQMR--AvgrascvdstgERIIFDDHVKltdDVEVV 963  nematode

2XRI_A         85 PFCTELTGIIQAMVDG----Q-P-SLQ--QVLERVDEWMAKEG----LLDPNvKSIFVTCGDWDLKVmLPGqcqylgLpV 152  human
Q12090        286 DLNSDFSGVHEIDRTNc---P-T-YKE--ALDVFLSENLINKNs---ILIGHgLENDLNVMRLFHNk------------V 343  Saccharomyces...
O16312        264 DYVTRWSGITPDMMEGv---T-T-TLG--DVQKAIQSLLPPDa----ILVGHsLEHDLQAMKMTHPf------------C 320  Caenorhabditi...
O76875        390 DYNTQYSGITETDLCSg---A-K-SLA--EVQRDLLQLITADT----ILIGHgLENDLRALRLVHNT------------L 446  fruit fly
EDN61859      267 DYLTRYSGITEEKLTVg--aK-K-TLR--EVQKDLLKIISRSD----ILIGHsLQNDLKVMKLKHPl------------V 324  Saccharomyces...
XP_003318228   90 DYNTRFSGVTEADVAK----TsI-TLP--QVQAILLSFFSAQT----ILIGHsLESDLLALKLIH------------StV 146  chimpanzee
NP_741135     313 DPNTEFSGLTMEQINS----A-PdTLK--TCHQKLFKYVNADT----ILIGHsLESDLKAMRVVHKN------------V 369  nematode
NP_593053     949 DYLTEYSGIHPGDLDPdrspY-N-VVPlkVAYKKLRLLVNAGc----IFVGHgLQKDFRIINLLVPP--EQ--------V 1012 Schizosacchar...
NP_011421     970 DYLTRYSGILPGDLDPekstK-R-LVRrnVVYRKVWLLMQLGc----VFVGHgLNNDFKHININVPRnQ----------I 1033 Saccharomyces...
NP_498519     964 DYLTKFSGIVKADLCPt---T-S-EKYl-TTHKRLLLRMHVLIqrgvTFVGHaLHNDFTVLNVHVAEs----------qI 1027 nematode

2XRI_A        153 ADY-FKqwinLKKAYSFAmgcwpKNGLLDMNKGLSLQHIGr------pHSGIDDCKNIANIMKTLAYRGF 215  human
Q12090        344 IDT-AI----LYSRTKf------KVSLKNLAFEVLSRKIQng-----eHDSSQDAIATMDVVKVKIGISP 397  Saccharomyces cerevisia...
O16312        321 LDV-GH----VLNYTNSNte--fRNSLKNLTELFLGAQIQse----fgHCSYEDAWAAMRLAQLKLEKGL 379  Caenorhabditis elegans
O76875        447 IDTsIS----FPHCNGFPy----RRALRHLTKVHLKRDIQagdg-ttgHSSFEDSRACMELMLWRVNREL 507  fruit fly
EDN61859      325 VDT-AI----IYHHKAGDp---fKPSLKYLSETFLNKSIQng-----eHDSVEDARACLELTKLKILNGL 381  Saccharomyces cerevisia...
XP_003318228  147 LDT-AV----LFPHYLGFp---yKRSLRNLAADYLGQIIQdsq---dgHNSSEDANACLQLVMWKVRQRA 205  chimpanzee
NP_741135     370 IDT-AI----LFRSTR-Dt----KVALKVLSAKLLHKNIQgdnedaigHDSMEDALTCVDLIFYGLRNPE 429  nematode
NP_593053    1013 VDT-VD----LFFLSSRQr----KLSLKFLAWYLLDEEIQlt-----eHDSIEDALTALKLYDCYDKLKS 1068 Schizosaccharomyces pom...
NP_011421    1034 RDTaIY----FLQGKR-------YLSLRYLAYVLLGMNIQeg-----nHDSIEDAHTALILYKKYLHLKE 1087 Saccharomyces cerevisia...
NP_498519    1028 IDT-VT----LMRLGTQR-----MLSLQFLVKEILGETIQme-----aHDSVVDARYALKLYRKYLEIKE 1082 nematode