1A35_A 186 LFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPS---PPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIK 262 human AAC18301 287 LFRGRGDHPKTGKLKTRVVPEQVIINIGKDSVIPS---PPPGHNWKEVRHDNTVTWLATWNENVNNNVKYVFLSAGSSLK 363 Pneumocystis ... CAA29559 337 LFRGRGSHPKTGSLKRRVYPEQITINIGEGVPVPE---PLPGHQWAEVKHDNTVTWLATWHENINNNVKYVFLAAGSSLK 413 fission yeast EEU08906 268 LFRGRGAHPKTGKLKRRVNPEDIVLNLSKDAPVPP---APEGHKWGEIRHDNTVQWLAMWRENIFNSFKYVRLAANSSLK 344 Saccharomyces... AAO19447 393 LFRGRGEHPKTGRVKARVQPEQITINIGKEARVPP---PPEGHKWKEVKHDQEGTWLAMWQENINGNYKYVMLAANSDVK 469 Emericella ni... AAC39319 393 LFRGRGEHPKTGRVKARVQPEQITINIGKEARVPP---PPEGHKWKEVKHDQEGTWLAMWQENINGNYKYVMLAANSDVK 469 Emericella ni... AAB39507 304 LFRGRGAHPKTGKLKRRVVSEQVTLNLGKDAKIPE---PPAGHQWGEIRHDNEVTWLAMWKENISDSLKYVRFANNSSVK 380 Candida albicans Q00313 302 LFRGRGAHPKTGKLKRRVVSEQVTLNLGKDAKIPE---PPAGHQWGEIRHDNEVTWLAMWKENISDSLKYVRFANNSSVK 378 Candida albicans AAC14193 553 LFLGRGAHPKTGLVKKRIEAEDITINIGKGVPVPE---PPPGHKWCKVVHDDKVAWLAMWKENINNGFKYVWLHASSAVK 629 Physarum poly... XP_001351663 308 LFRGRGEHPKQGLLKKRIFPEDVVINISKDAPVPRlydNMCGHNWGDIYHDNKVTWLAYYKDSINDQIKYTFLSAQSKFK 387 Plasmodium fa...
1A35_A 263 GEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEgETADTVGCCSLRVEHINLHP 342 human AAC18301 364 GQSDLKKYEKARELKLYIDNIRKQYRKELEDKLMEVRQRATAMYLIDLFALRAGNEKGE-DEADTVGCCSLRYEHISLSP 442 Pneumocystis ... CAA29559 414 GQSDLKKYEKSRKLKDYIDDIRKGYRKDLKNELTVERQRGTAMYLIDVFALRAGNEKGE-DEADTVGCCSLRYEHVTLKP 492 fission yeast EEU08906 345 GQSDYKKFEKARQLKSYIDAIRRDYTRNLKSKVMLERQKAVAIYLIDVFALRAGGEKSE-DEADTVGCCSLRYEHVTLKP 423 Saccharomyces... AAO19447 470 GQSDYKKFEKARELKKHIARIRKDYQKNLKHELMVERQKATAVYLIDQFALRAGNEKGE-DEAETVGCCSLKYENVTLKP 548 Emericella ni... AAC39319 470 GQSDYKKFEKARELKKHIARIRKDYQKNLKHELMVERQKATAVYLIDQFALRAGNEKGE-DEAETVGCCSLKYENVTLKP 548 Emericella ni... AAB39507 381 GQSDFKKFETARKLRDHVDSIRKDYTKMLKSEKMQDRQMATAMYLIDVFALRAGGEKGE-DEADTVGCCSLRYEHVTLKP 459 Candida albicans Q00313 379 GQSDFKKFETARKLRDHVDSIRKDYTKMLKSEKMQDRQMATAMYLIDVFALRAGGEKGE-DEADTVGCCSLRYEHVTLKP 457 Candida albicans AAC14193 630 GRSDMKKFEVARKLKDHIEKIRKKYLKELGSEELEERQRATAIYLIDRLALRVGNEKDE-DTADTVGCCSLRVEHVTLKE 708 Physarum poly... XP_001351663 388 GYKDLMKYENARKLKSCVHKIREDYKNKMKNKNIIDKQLGTAVYLIDFLALRVGGEKDIdEEADTVGCCSLRVEHISFAH 467 Plasmodium fa...
1A35_A 343 ELDGQeyv-----------------------------veFDFLGKDSIRYYNKVPVEKRVFKNLQLFME-------N-KQ 385 human AAC18301 443 PNTVV----------------------------------FDFLGKDSIRYYNEVQVDPQVFKNLKIFKRs------P-KT 481 Pneumocystis ... CAA29559 493 PRTVV----------------------------------FDFLGKDSIRYYNEVEVDPQVFKNLKIFKR-------PpKK 531 fission yeast EEU08906 424 PNTVI----------------------------------FDFLGKDSIRFYQEVEVDKQVFKNLTIFKRp------P-KQ 462 Saccharomyces... AAO19447 549 PNKVI----------------------------------FDFLGKDSIRFYDEVEVDPQVFKNLKIFKKp------P-KK 587 Emericella ni... AAC39319 549 PNKVI----------------------------------FDFLGKDSIRFYDEVEVDPQVFKNLKIFKKp------P-KK 587 Emericella ni... AAB39507 460 PNKVI----------------------------------FDFLGKDSIRFYQEVEVDKQVFKNLRIFKKs------P-KQ 498 Candida albicans Q00313 458 PNKVI----------------------------------FDLLGKDSIRFYQEVEVDKQVFKNLRIFKKs------P-KQ 496 Candida albicans AAC14193 709 PASVT----------------------------------LDFLGKDSMRYHNTVDVDPRVFKNLSEFMYkggnkkaP-KK 753 Physarum poly... XP_001351663 468 DIPFKsvdskeqktndekvnkiplptnlesissedcyitLDFLGKDSIRYFNTVKIDKQAYINIIIFCK-------N-KN 539 Plasmodium fa...
1A35_A 386 PEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTa-------------------------------- 433 human AAC18301 482 EGDMLFDRLNTSKLNNHLTSLMPGLSAKVFRTHNASYTMSEQLKNTP--------------------------------- 528 Pneumocystis ... CAA29559 532 EGDLIFDRLSTNSLNKYLTSLMDGLSAKVFRTYNASYTMAEELKKMP--------------------------------- 578 fission yeast EEU08906 463 PGHQLFDRLDPSILNKYLQNYMPGLTAKVFRTYNASKTMQDQLDLIPn-------------------------------- 510 Saccharomyces... AAO19447 588 EGDEIFDRLTTSALNKHLSQYMPGLTAKVFRTYNASHTMSELLKSMHa-------------------------------- 635 Emericella ni... AAC39319 588 EGDEIFDRLTTSALNKHLSQYMPGLTAKVFRTYNASHTMSELLKSMHa-------------------------------- 635 Emericella ni... AAB39507 499 PGDDLFDRINPSLVNRQLQNYMKGLTAKVFRTYNASKTMQDQIDIIEn-------------------------------- 546 Candida albicans Q00313 497 PGDDLFDRINPSLVNRQLQNYMKGLTAKVFRTYNASKTMQDQIDIIEn-------------------------------- 544 Candida albicans AAC14193 754 PENDLFDQLTTSSLNKYLKGFMENLSAKVFRTYNASLTLEKELAKMPes------------------------------- 802 Physarum poly... XP_001351663 540 RDEGVFDQITCSKLNEYLKEIMPTLSAKVFRTYNASITLDQQLKRIKevygkttyslysgetelhkskkrksshltsdtn 619 Plasmodium fa...
1A35_A 434 -----------------------------------------------PDENIPAKILSYNRANRAVAILCNHQRAPPKTF 466 human AAC18301 529 -----------------------------------------------KDASISDKVLAYNRANRMVAILCNHQRTISKTH 561 Pneumocystis ... CAA29559 579 -----------------------------------------------KNLTLADKILFYNRANRTVAILCNHQRSVTKNH 611 fission yeast EEU08906 511 -----------------------------------------------K-GSVAEKILKYNAANRTVAILCNHQRTVTKGH 542 Saccharomyces... AAO19447 636 ------------------------------------------------TGNNAEKVKAYNDANRKVAILCNHKRTVGAAH 667 Emericella ni... AAC39319 636 ------------------------------------------------TGNNAEKVKAYNDANRKVAILCNHKRTVGAVT 667 Emericella ni... AAB39507 547 ------------------------------------------------EGTVAEKVAKFNAANRTVAILCNHQRTVSKTH 578 Candida albicans Q00313 545 ------------------------------------------------EGTVAEKVAKFNAANRTVAILCNHQRTVSKTH 576 Candida albicans AAC14193 803 ----------------------------------------------lIKATADEKVLFYNRCNREVAILCNHQRSLSKTH 836 Physarum poly... XP_001351663 620 ilsdasdstindvnneydenginkklsyattvgkendvddknspievDVSNINELINFYNNANREVAILCNHQRSIPKQH 699 Plasmodium fa...
1A35_A 467 EKSMMNLQTKIDAKKEQLA------------------------------DA----------------R------------ 488 human AAC18301 562 SAQMERIEDKILALKYQKIrlrkailtldpkl-----eksrpdlseavsDI----------------D------------ 608 Pneumocystis ... CAA29559 612 DVQMERFAERIKALQYQRMrlrkmml-----------------nlepklAK----------------S------------ 646 fission yeast EEU08906 543 AQTVEKANNRIQELEWQKIrckrailqldkdllkkepkyfeeiddltkeDE----------------Atihkri-----i 601 Saccharomyces... AAO19447 668 AHQMEKMSERIKGQRYQKWrlkqmmldldpsl----kkkkgaqffeldeDI----------------Dkewikehqafli 727 Emericella ni... AAC39319 668 RDQMEKMSERIKGQRYQKWrlkqmmldldpsl----kkkkgaqffeldeDI----------------Dkewikehqafli 727 Emericella ni... AAB39507 579 GDSVQRINDKLKKFMWQKIrlkkmilqlepkl-----kkkdskyfeeidDLlkediehihhtiikrqR------------ 641 Candida albicans Q00313 577 GDSVQRINDKLKKFMWQKIrlkkmilqlepkl-----kkkdskyfeeidDLikediehihhtiikrqR------------ 639 Candida albicans AAC14193 837 TETMGKIDEKIAEFKKEKLqqqiaylkgkg---------kkpvlsdsesDE----------------Dtpkkatp---kk 888 Physarum poly... XP_001351663 700 DTTMSKIKKQIELYNEDIKeykkylq-----------------hlkknsDK----------------Kf----------- 735 Plasmodium fa...
1A35_A 489 ----R----------------D----------------------------LKSA------KADAK--------------V 500 human AAC18301 609 ----EdwikehqkvliekeydK----------------------------IKRKfqkdneKLISQ--------------N 642 Pneumocystis ... CAA29559 647 ----K----------------PellakeegitdswivkhhetlyelekekIKKKfdreneKLAAE--------------D 692 fission yeast EEU08906 602 dreiE----------------K----------------------------YQRKfvrendKRKFE--------------K 623 Saccharomyces... AAO19447 728 eeqaQ----------------K----------------------------IKKKfekdneKLLAE--------------G 749 Emericella ni... AAC39319 728 eeqaQ----------------K----------------------------IKKKfekdneKLLAE--------------G 749 Emericella ni... AAB39507 642 ----E----------------Q----------------------------AKKKlerdneKLKLE--------------G 659 Candida albicans Q00313 640 ----E----------------Q----------------------------AKKKlerdneKLKLE--------------G 657 Candida albicans AAC14193 889 atpkK----------------E----------------------------TKSSdeatpnKKRKKdddeeeaddfketpK 924 Physarum poly... XP_001351663 736 ---------------------I----------------------------FVSKvstldgTLRPN--------------K 752 Plasmodium fa...
1A35_A 501 -----------------MKDAKTK-KVVESKKK---------------AVQRLEEQLMKLEVQATDREENKQIALGTSKL 547 human AAC18301 643 etpmpesr-lekflekiNEMKEEF-KIENEKGRvesktrgitietldlQIKKINERIHQMKALMIDKAQNKTTALGTSKI 720 Pneumocystis ... CAA29559 693 pksmlpeselevrlkaaDELKKAL-DAELKSKKvdpgrss--meqlekRLNKLNERINVMRTQMIDKDENKTTALGTSKI 769 fission yeast EEU08906 624 eellpesq-lkewlekvDEKKQEF-EKELKTGEvelksswnsvekikaQVEKLEQRIQTSSIQLKDKEENSQVSLGTSKI 701 Saccharomyces... AAO19447 750 ekemkase-letrleavKELEKKF-NKENKTGKveaegrsptvekleaSITKLQQRIENMELQAQDKEDNKEVALGTSKI 827 Emericella ni... AAC39319 750 ekemkase-letrleavKELEKKF-NKENKTGKveaegrsptvekleaSITKLQQRIENMELQAQDKEDNKEVALGTSKI 827 Emericella ni... AAB39507 660 kplltesd-ikdkldkiDELEKEY-QKELKTGKpivtkna-tveklkqQIETLENKILNVSIQLKDKEDNSEVSLGTSKM 736 Candida albicans Q00313 658 kplltesd-ikdkldkiDELEKEY-QKELKTGKpivtkna-tveklkqQIETLENRILNVSIQLKDKEDNSEVSLGTSKM 734 Candida albicans AAC14193 925 -----------------KKVKRALpDSVEKCKA---------------AIERVDTSINKWNIKKTEKDELKSVALTTSKI 972 Physarum poly... XP_001351663 753 -------------------VKENM-KEESCKKK---------------LIT-LIKKVELLNNQMKVRDDNKTIALGTSKI 796 Plasmodium fa...
1A35_A 548 NFLDPRITVAWCKKWG 563 human AAC18301 721 NYIDPRLTYAWCAKYG 736 Pneumocystis carinii CAA29559 770 NYIDPRLTYSFSKRED 785 fission yeast EEU08906 702 NYIDPRLSVVFCKKYD 717 Saccharomyces cerevisiae JAY291 AAO19447 828 NYIDPRLTVVFSKKFK 843 Emericella nidulans AAC39319 828 NYIDPRLTVVFSKKFK 843 Emericella nidulans AAB39507 737 NYIDPRLIVMFSKKFD 752 Candida albicans Q00313 735 NYIDPRLIVMFSKKFD 750 Candida albicans AAC14193 973 NYIDPRITAAWAKRVG 988 Physarum polycephalum XP_001351663 797 NYMDPRITVAFCKKFE 812 Plasmodium falciparum 3D7
Jiyao W et al.(2023). "The conserved domain database in 2023.",