Conserved Protein Domain Family
pfkB

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TIGR03828: pfkB 
1-phosphofructokinase
This enzyme acts in concert with the fructose-specific phosphotransferase system (PTS) which imports fructose as fructose-1-phosphate. The action of 1-phosphofructokinase results in beta-D-fructose-1,6-bisphosphate and is an entry point into glycolysis (GenProp0688).
Statistics
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PSSM-Id: 274804
Aligned: 29 rows
Threshold Bit Score: 263.681
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_003851833   2 ILTFTPNPSIDKTLQLDSvLTRGAVQRLSGVQTVAGGKGINVAVALAKAQADTVALYP--AHPEDPFNKLIRESQIPAQR 79  Corynebacterium...
WP_026699402  12 IYTCTMNTAVDLFVETDE-LLPDVVNRTKDEDYQPNGKGVNISFMLKRLGLDNTALGFtgGFTGRFIENELLNEKIVTDF 90  Bacillus lichen...
WP_002263695   3 IYTCTMNLAIDLFIETEH-LYESKVNRALSDDIQANGKGVNVSFIMKRLGLENTALGFsgGFTGKYVADNLEAEGIAAPF 81  Streptococcus m...
WP_011161363   2 IYTITLNPAIDLVIITKK-LEPNIVNRTENFELQPNGKGVNVSFILKKMGIENVATGIggGFTLDYITAGLTEKGISNNF 80  Lactobacillus j...
WP_011233185   2 IYTLTLNSAIDMNIFSDP-LQPNIVNRTHHTEFCPNGKGVNVALVLDHFQIPAHILGIfgGFTGHYIVESLRTKKMPVTP 80  Salmonella ente...
WP_010985120   2 ILTVTPNPSLDRTYEVPS-LDRGEVIRATGERMDPGGKGVNVSRAVAAAGQRTVAVLPlgGAPGAFVAALLDAQGIDVAP 80  Streptomyces av...
WP_011291143   2 ILTVTPNPSVDRTLEIDT-YVRGAVIRIHNAMAHAGGKGVNVSRALRNHGVQTVAVLPvgGAEGAQLTALLGEHGIAAVT 80  Thermobifida fusca
WP_013068251   5 IATVSLNSAVDQTVTVPG-FTADAVNRVAASRIDAGGKGVNVASFLAHVGHGVAVTGLlgAENAALFARHFAATGLVDAC 83  Rhodobacter cap...
WP_011185602   2 IVTLTANPSLDRAVALAGpLRPGEVQFAASSREDAGGKGITVARVIAAAGVSTLAVLPlaGD--DPFGAVLRSSAVPTRP 79  Leifsonia xyli
WP_011211781   5 ILTVTMNPAYDTTYRVER-FERGRAHRVRSVEQRIGGKGINVTRVLNQLGRYARATGF-----ADHAFAAAAELELPVDF 78  Nocardia farcinica
WP_003851833  80 VTIRGEVRINTTVTe-pDG-TTTKLNIQGPQIH-EDELQALQKNLLeRT-ARC-S--WAVLAGSLPPGVPTDWYVHLTKL 152 Corynebacterium...
WP_026699402  91 VEVEGISRINIFINs----tREFKIVNKGPLIS-EARKQELINKIR-QI-PPG-R--FLFISGSLPRGVPDDMYLSLSEI 160 Bacillus lichen...
WP_002263695  82 VEVEGLTRINVFTKvnaTC-QEFKLVNQGPLVN-EAAQCRLLQQIS-KF-KKG-D--YLVVSGSLPRGVPSQILYDIAKL 154 Streptococcus m...
WP_011161363  81 LKVKEPTRINVFTRv-iDQnREYKEVNPGPEVS-EKVQEQFLKYLRtTL-KES-D--TLIISGSFSRGINQDYLVKIAKV 154 Lactobacillus j...
WP_011233185  81 AWVEEPTRINIFIHd--GQ-QEYKLVNPGSYIP-DECKQQIITIIS-QL-PDA-E--YLVISGSLPQGIESRFYAEIMHI 151 Salmonella ente...
WP_010985120  81 VPVAGATRSNISVAe-pDG-TLTKINAPGPELT-PAEAELLLETVReQY-RAG-DttWITCCGSLPRGLAPSWYADLVAR 155 Streptomyces av...
WP_011291143  81 VPVAAVTRCNITTAe-tDG-TTTQLNVPGASLS-EAEVAALLRAVEsQLrHHP-K--WLVAGGSLPQGTPTDFYVRLSVL 154 Thermobifida fusca
WP_013068251  84 QRLPGATRTNVKIVdplQD-QVTDLNFPGIAAG-PADLDAVAATLTeLL-AQGlD--WVALCGSLPAGIGAEAYAELAAL 158 Rhodobacter cap...
WP_011185602  80 VAIHGHARANLTITd-pAG-ATTKLNLPGATLR-AEEAETLGEAVVdAC-AGA-S--WLVLAGSLPPGVGDDFYVTVIRA 152 Leifsonia xyli
WP_011211781  79 VHALPWVRRTVVISesdDG-TATALAEPGARVSnPHACEQLAVRVAgLL-PDL-G--GLVISGSLPGGIDAGLPAQIADS 153 Nocardia farcinica
WP_003851833 153 LNARh--pSLRIAIDTSDVPLQ-KVGEAF-GNcalsLIKPNGMELGQLVGldgyvlekeAAQG-N---FDPVVSAARKAI 224 Corynebacterium...
WP_026699402 161 AAEN----KLKLILDISSPVLL-DCLSYH-PY----LIKPNEQELAAFFS---------RKKAlS---EEEIIHCGKELL 218 Bacillus lichen...
WP_002263695 155 CYEK----GVNLIFDVSDCIIM-DSLSFH-PF----LLKPNEEELATWFG---------KNQL-E---EEQLISYAKQLI 211 Streptococcus m...
WP_011161363 155 MADK----KVKLVIDSSSKAVL-DTLPYY-PY----LLKPNDQELASFFD---------LNEKlD---QEKIIKLARKLI 212 Lactobacillus j...
WP_011233185 152 CQQK----NIGVILDISHPSLR-QLLEFK-PL----LIKPNDEEVKAIFG---------LTVS-D---DNDAKNALTTLH 208 Salmonella ente...
WP_010985120 156 AHAA----GARIALDTSGPALL-EALRER-PD----VVKPNAEELAEAVG---------RPLA-T---VGDAVKAAEELR 212 Streptomyces av...
WP_011291143 155 ARRY----GVPIAVDTSGEPLA-VTARAGaAN----LLKPNHHELAELLD---------RELT-T---LGDVVDATREVL 212 Thermobifida fusca
WP_013068251 159 ARKG----GARVALDTSGPALG-LALAAR-PD----IVKPNVAELGAHLG---------RTLT-G---LESVREAARDLA 215 Rhodobacter cap...
WP_011185602 153 VRERwgeaAPRVAVDTAGEALRtVVADAR-PD----LIKPNDDELAELSG---------AALD-PgdvERSVLRVARTLV 217 Leifsonia xyli
WP_011211781 154 AVAA----GVPTICDVEDEALR-LVAKVP-GV----VLMPNAAELTFLTG---------DEPQ-T---AREVVRAARPLV 210 Nocardia farcinica
WP_003851833 225 LQGVENVLVTLGAAGAVLVTKD-HAWKATPPPITVLSTVGAGDASLAGFILASEDGLPPE--KCLAQAVAYGAAAASFAG 301 Corynebacterium...
WP_026699402 219 DRGAERVLISRGKDGALYLDRQ-RTLKATAAKGKVVNTACAGDAMLAVFVGKQELGCSVP--EALRHASAAGSLTAFSKG 295 Bacillus lichen...
WP_002263695 212 VKGARHVLLSLGQDGAIFIDSHfNVYQANAPRGKVVNTACAGDTLLGTFLAGFIRQESLE--RVLAKSVAAGSSTAFRSG 289 Streptococcus m...
WP_011161363 213 DDGCKNVLVSLGDSGAALIDKN-HAYFGNAPKISVINTAGAGDTMLGTFIGKKELGCNTV--EALKFAIAAGSDTASRMG 289 Lactobacillus j...
WP_011233185 209 ALGAQNVLLTLGAKGMYFSNGI-DYWFCSAPTVDLVSSACAGDAALAAFLSQWLSTGEVE--YALSLASATGADVASSAG 285 Salmonella ente...
WP_010985120 213 GLGAGAVLASLGADGQLLVDAS-GTWFGSARVDAVRSDVGAGDSSLAGFLIA---GGSGA--DALASAVAHGAAAVQLPG 286 Streptomyces av...
WP_011291143 213 SWGNDAALVTLGSYGALLVEPD-RFWWAGGPPIVPRSTVGAGDSTLAGFLF---DDGAPE--ERLRRAVSWGSAAVALPG 286 Thermobifida fusca
WP_013068251 216 ASGVGLVAVSMGAGGAVLVRGA-EAVLAIPPATPIASTVGAGDAMVAGLIHAATLGLDLA--ETARLATAFSLGALGEIG 292 Rhodobacter cap...
WP_011185602 218 PGRVGAALITLGSRGSILVTPS-GGYVAAAPRIRVQSTVGAGDSALAGYLLADVAGASAP--QRLAGAIRYGSAAAALPG 294 Leifsonia xyli
WP_011211781 211 DAGVRAVVATRGARGMVAVTPE-GAWWGGLPQPLAGNPTGAGDSAAAAVIAALAGGGEPDwpAILTDAVATAAAAVVIPV 289 Nocardia farcinica
WP_003851833 302 thMPYPHQIDVNHTPVTL 319 Corynebacterium diphtheriae
WP_026699402 296 --LGDVSKLDQTASQIQI 311 Bacillus licheniformis
WP_002263695 290 --ITDFSDVNELKEQIMV 305 Streptococcus mutans
WP_011161363 290 --LTDFE-LEKYLNEIHV 304 Lactobacillus johnsonii
WP_011233185 286 --LGQLAAIETLLSQIHV 301 Salmonella enterica
WP_010985120 287 svMPKPADLDPSAVTVTa 304 Streptomyces avermitilis
WP_011291143 287 ttIPGPADINdegvvvvp 304 Thermobifida fusca
WP_013068251 293 phLPPPERLAALARTVTV 310 Rhodobacter capsulatus
WP_011185602 295 tqAPHPADLPR--DDIRV 310 Leifsonia xyli
WP_011211781 290 agEIDRGLRTELAPTVRI 307 Nocardia farcinica
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