Conserved Protein Domain Family
GCD2

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COG1184: GCD2 
Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family [Translation, ribosomal structure and biogenesis]
Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family is part of the Pathway/BioSystem: Translation factors
Statistics
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PSSM-Id: 440797
Aligned: 105 rows
Threshold Bit Score: 184.666
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_004214804   1 MdsdpdpdpnhpvvdPAVTDTAADIAAMRIRGAAAIADAAAAALATQAERS---KA---TDPAAFERDLRAGARELYETR 74 
WP_011957735   1 Msgrt------mtrgVEVVESVAAIAVDNRQGAAQIAEQAADLMIRRAEAS---RS---SSPQEFRRDLRNFGWSLIHAQ 68 
WP_004041813 122 Lwa----------tyRRVAPAVETVADDETHGSTWISLRALEVLRDAAAEA------------DSLEAVASVARRLRDAR 179
WP_011322251 112 virdretvpklwaayRAVGPAVETVRMDTDRGAAALSLRALEALRDRAAEV------------DDYAAVAETGRALLAAR 179
WP_006055303 112 airnrptvprlwetwRRVAPTVETVRTDRTHGSAWISARALEALRDAAIEA------------DDWAAVAKIGRELRDAR 179
WP_008416001  92 eirrretpagswraySAVAPTVESVRGDRTQGSAAVSVRALEVLRDRAGEG------------ADWPALVEQANALLEAR 159
WP_008526289 122 Lwa----------syDRVRPTVEAVREDRDHGSAWLSIRALEILRDEAGVRt------wGEGSGGWDAVAAIARDLRDAR 185
WP_050047741 113 ailrretvpdlwksyWRVAPTVETVRADEDHGSAYVSLRALEVLRDAAALAv-------ERGKGNWDHLAKTAQGLLDAR 185
WP_086887444 149 Lwt----------ayERVAPTVRSITADDTHGAAWLSIRALEVLRDRAGLLvseRAeyrADPAGEREELAALAGRLLEAR 218
WP_119816103 110 airdretvpmlwetyCRIAPTVETIRTDEVHGASWLSIRALEVLRDGAGTA------------DEWETIAELAGELVDAR 177
WP_004214804  75 PTAVSLPNALRYVLRg---MEGE---TVAALRDSTIERADTFRTELEQAQSTLGEIGSNRLRDG-------DVVMTHCHS 141
WP_011957735  69 PVMAPLVNLVNRVLWaieePQ-----SLNDLIRTVVEVAEGFKHQLRQHALHVAEGALALISDG-------ITIVTLSYS 136
WP_004041813 180 PNMAAVENRVNRVMAe-----------sDSDPESVRRRAEAAIDAAAEADDAAAARAAELIRERg-----vDRLATLSRS 243
WP_011322251 180 PSMAVVRNRISRVLSa-----------aGRTPMAVCQAAMDACEAALEAGAEAASRAADSLG---------ERVLTLSRS 239
WP_006055303 180 PSMAAVCNRVNHVLSt-----------sERTPESVATVAIRELDAAFESDEKAARTLVRRLRDAe-----vSGVATLSRS 243
WP_008416001 160 PSMAAVMNRINRAMAea---------agTADAVALERATRAGIDRALAADGRAAENATKRVEG---------TVLTLSRS 221
WP_008526289 186 PSMPVVANRVNRVMAr-----------aDRSPAAVEHIAREGLEAAFAADGGAAEHAAELLPD---------RIATLSRS 245
WP_050047741 186 PSMAAVRNRVNRVLSva---------ssDRTSAAVERAATDAIGAALAADWSAAETARKHVDG--------ERVVTLSRS 248
WP_086887444 219 PAMAVLRNRVNRVMGraesEAGSgegAADADAPAVLTVALETIDRAVDADEQAATTASDRIDG---------TVLTLSRS 289
WP_119816103 178 PGMVAIGNRVNRVMEavvaEGdl--qEAVPSLDLVHDRTVAAIERAVEADGTASRSVADLLEPGgrfrkrgGPIVTLSRS 255
WP_004214804 142 TDALACIEA--------ALESGK-RIEAIVKETRPRKQGHIMARQLREL---GVPVTLIVDNAARRYL----DEADHVLV 205
WP_011957735 137 TTVQHALRH--------AQRAGR-RFRVVCGESRPILEGRQTAAILAEY---GIPTQLVIDAELPAHI----AQAQLVIV 200
WP_004041813 244 GTVLAALEA--------AEAA---AVAVLVSESRPGGEGVGVAERLARD---GRDVTLTTDAALPGLVa--aGGADAVLL 307
WP_011322251 240 GTVEAAILE--------AEPS-----RVVVAESRPGREGVGTAERLAEA---GIDVTVCADAAVTAALs--tADIETVVF 301
WP_006055303 244 GTVSAALRK--------LDPT-----SLLAAESRPEREGVTVAETVAEEt--DAAVTVTTEAALPAALsrceTAVDAVVV 308
WP_008416001 222 GTVRGAFSA--------GDPD-----RVIVLESRPDREGIDVAEDLAED----ADVTVTLDAAIAHVM----ADVDAVLV 280
WP_008526289 246 GTVRTAIER--------ADPE-----AVLVAQSRPGGEGVGVAEELAGE----RDVTIAADADLAWAIh--eWESGAVIV 306
WP_050047741 249 GTVFAALSS--------GAPA-----SVVVAESRPGGEGVGVAEDLADE---GLDVTLTTDANVPAAV----ADATVCLF 308
WP_086887444 290 GTVLAALER--------AAPS-----RIYVAESRPAREGIDVAERLASVstvDAPITVCTDAAIAHVLg--rEAVSRVVV 354
WP_119816103 256 ETVLAALRElrsrarpiGDPDGAaALRVIVGESRPDREGVGVAETLSDS---DIEVTLAADSALPWLLe--rDDAACVLV 330
WP_004214804 206 GADSIAADGSVINKVGTSGLAVNARERGVPVVVAAQTIKLHPDTMtgHTVAIEMRD-------EREVLSMEErteiepsg 278
WP_011957735 201 GADMLSTQG-LVNKVGTYGMALTAHAKGVGFYALCGSEKFVLPGF--RPLEQLDRP-------RSEIWAEAP-------- 262
WP_004041813 308 GADSVLASGGVVNKVGSLPAALAAARADVPVFAVCARDKVRGDDR----FAGED---------AGALYDGE--------- 365
WP_011322251 302 GADTVLADGSVINKVGSHPAALAAADTDIECLAVCSRDKMSPTTA----ADIETGP-------PEAVYDGD--------- 361
WP_006055303 309 GADAVHPDGSVVNKTGTSVLASAAQSAGVPVYVVAASDKVRPAGT----ASRDAADemcaespHEAVYDGD--------- 375
WP_008416001 281 GADTVLADGSVVNKVGTRTAAVVAAREGVPVYAVAAVDKISPATE----PVLESID-------SEAITDRE--------- 340
WP_008526289 307 GADAIRPDGGVLNKAGTRSAALAAAHEGVPVLVAAAADKVDADGE----REIESVD-------PGRIYDGT--------- 366
WP_050047741 309 GADTVLPDGSVVNKVGSRAMALASRDTGIPCYAVCASDKIAPDST----IHVDDGD-------PETLYRGD--------- 368
WP_086887444 355 GADAIQPDGSVVNKTGTRAAAIAADSAGVPVTVVAASDKISTREG----VNLESGS-------REAVYDGE--------- 414
WP_119816103 331 GADTIDPSGGVYNKAGTYGLALAADRAGVPMVVVASTPKIAPTAG----FEQEWSD-------PAAVYGG---------- 389
WP_004214804 279 etarsaaGDgngdearrqdengLTVENPAFDVTPPRHIDAIVTEHGQFPPESIVTLMRELFGETT-AEP 346
WP_011957735 263 -------PN-------------VHIRNRYFDLTPLELLSGIVTERGVLPVAAIEAWLASTHLHPAlAHE 311
WP_004041813 366 -------AA-------------IGTENPLFEVVPADSLSGVVTESGVLNAGDIGAVADEHAALAAwDD- 413
WP_011322251 362 -------AD-------------VSVYNPAFERVPASLVDGIVTEEGRLPTAAAAAIAERHADHRDwRP- 409
WP_006055303 376 -------AD-------------VDVFAPTFERVSADLVDGLATEKGLLDAAAVRRVAVEHAEHAAwTD- 423
WP_008416001 341 -------A--------------VAVECPLFDRTPPDLITGLITEEGLLNATAIGERAADHERRARwKEP 388
WP_008526289 367 -------AD-------------LTVRSPLFDVTPPELVDAICTDRGVLEPEDIEAVAAEHRANAEwEDR 415
WP_050047741 369 -------AD-------------LTVDNPTFERVPASLLNGVITEADVLDDEQIESLSAVHAARANwSRT 417
WP_086887444 415 -------AA-------------VDVVNPTFDVTPADCVAEIVTEDGVIEPSDVATVAEKLRALEGwRDQ 463
WP_119816103 390 -------SG-------------IDVTTPRFDRTPPGLVTAIVTEHGTLSTADVRSFAAKHRENAAwNRR 438
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