4DWL


Conserved Protein Domain Family
Avd_like

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cd16376: Avd_like 
Click on image for an interactive view with Cn3D
diversity-generating retroelement protein bAvd and similar proteins
The bacterial accessory variability determinant (bAvd) protein, together with a reverse transcriptase, is involved in retrohoming processes as part of a diversity-generating retroelement (DGR), a type of system that is involved in generating sequence variation in bacterial proteins by inserting coding information from a template region into a variable region of a protein coding gene. bAvd forms homopentamers and interacts with the reverse transcriptase as well as with DNA and/or RNA.
Statistics
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PSSM-Id: 319868
Aligned: 220 rows
Threshold Bit Score: 54.0788
Created: 28-Jan-2016
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
pentamer
Conserved site includes 27 residues -Click on image for an interactive view with Cn3D
Feature 1:pentamer interface [polypeptide binding site]
Evidence:
  • Structure:4DWL: Avd molecule from Bordetella bacteriophage DGR forms homopentamer, contacts at 4A

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1         #   #  ##  #   #        ## ## ## ##  #  ##  #   #                     ##  ##  #
4DWL_A        19 IVERYERVISYLYPIAQSIPR----KHGVAREXFLKCLLGQVELFIVAGK-----------SNQVSKLYAADAGLAXLRF 83  Bordetella phag...
CDC75062       6 LRQRIVRSMIRVGERTNNMRKp---EKFEYRKHMTAAFMDMLELCIEANRar--------gQRRVELQNKMDTKLDVLRS 74  Eubacterium rec...
WP_010457030  12 IVTKAKELCSYIITVTQKSPKq---FRFTIVTRLQNLALDIIGEIYKANDvfvnrgdfnalNFRLSLQREAMTNIKLLAY 88  Succinivibriona...
CDB24557      11 VVTSAKNLCSYVLIATNKSPKt---FRFTLVSRLQNLTLDIIENVYRANEifvqsknlqnmQKRLEFQHSALTDIKILAY 87  Clostridium sp....
CCY46257       7 ILNNTYKTINYINKILVNYPK----KEMVLKQNIEKNNYELIECIFAYNVnd-------ssRIKEKYLKDLLVKLSMSDF 75  Firmicutes bact...
CCY68997      10 VIVKAKELTLHTIKITSNCKKfpkkYRFTVCDRMQRKAMDIYESLLEANRill-----kdlIKRNDLQTKAILCCDELLF 84  Clostridium sp....
WP_034443072   8 ILATAERMETWLHRTLEKIPKy---ARFPVYAQMKGTMRILRRLILECNQa----------RDKTSYFTKIDLELLLLRS 74  Cloacibacillus ...
WP_051073274   1 MVADLIDYTLNLTDNAKHFPKk---IRFTIVNRIQERVLSIYENLLEANEifpir-nesdkAKRLELQRAALTDCKLLLF 76  Dehalobacter sp...
WP_021750538  13 KAKDLVNHTLQLTNNTKLFPKk---VRFTLCQRMQNLSIQILHDIIAANEiyprs--vaemNTRLDLQKEVLTNCKVFLN 87  Oscillibacter
WP_021751066  23 VADKMIGFTLSTTDNPKRFPKk---IRFSVTNKIQGHALAIYDYLVEANEifpim-ddqdkADRLKLQRAALTECKKLLH 98  Oscillibacter
Feature 1        # ##                                    
4DWL_A        84 WLRFLAgiqkphaXTPHQVETAQVLIAEVGRILGSWIARV 123 Bordetella phage BPP-1
CDC75062      75 LVDTAVspe-drlISPGLHEVWSKELNEIGRMLGGWKKSN 113 Eubacterium rectale CAG:36
WP_010457030  89 YAELALtm---naILMKQYCQIAKLTTDCQNLLGAWMNSD 125 Succinivibrionaceae bacterium WG-1
CDB24557      88 MALLAReq---gcILPKQYEQISKLASDCQYLLGAWIKSD 124 Clostridium sp. CAG:557
CCY46257      76 YTRVSYdk---kiISRHQFEVISKFLLEVRRMVYGLKRKE 112 Firmicutes bacterium CAG:822
CCY68997      85 YIEMCLel---liIQPNSAEYWSKLVSDIKHMTIAWRAKD 121 Clostridium sp. CAG:678
WP_034443072  75 DVRVMLes---rlITPGEFKVWGEEIDKIGRQLGAWGKAC 111 Cloacibacillus evryensis
WP_051073274  77 YVELSKkr---gyIDAGTFEYWTKKTLDVKYMSAAWYKSE 113 Dehalobacter sp. FTH1
WP_021750538  88 FLDIALeq---gyIDIRRCEYWTGLTTDVKNLAASWRKKD 124 Oscillibacter
WP_021751066  99 MIQLSKdr---gyIDSGTFDYWTKLTVDVKCMTARWYDAE 135 Oscillibacter

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