Conserved Protein Domain Family
VRR_NUC

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smart00990: VRR_NUC 
This model contains proteins with the VRR-NUC domain.
It is associated with members of the PD-(D/E)XK nuclease superfamily, which include the type III restriction modification enzymes, for example StyLTI.
Statistics
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PSSM-Id: 214959
Aligned: 70 rows
Threshold Bit Score: 40.5704
Created: 13-Jul-2011
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
YP_001059176   79 RWQYKAEVCFDMYPEyasrgieAPIPF------LSS-----DK--EAGPGRRHTLNPFP-PGRKNLVQDGVKLIMLR--R 142  Burkholderia ...
ZP_05588939    18 RTVYRPEVAYDMRPD-------VPTPI------MSSq---dPL--QPHPFIPNWLNKYWpGGYAE-YKKLAGQGLIR--R 76   Burkholderia ...
YP_202188      73 LSRYKPEVNYDMTQQ-------PPAPI------MDS-----GLatKAHDWLKGWIDKYWdEPGKDRPPFRPRAGLIR--R 132  Xanthomonas o...
ZP_06880302    75 RSPYKPEVSYDMTKN-------PPQPI------LDSq---tGN--SPHGWIPGWISKYWdEDP-EHPPFKPGKGMIR--R 133  Pseudomonas a...
NP_928788      77 LWPYKAEVVFAIRGP-------KDVPLpmlatsLAS-----KQ--RYSDNLPQSSNPFArPSADDVEKFGVK--RIR--R 138  Photorhabdus ...
XP_001469437 1614 ldilRAIPLEPLWRL-------LRCLY------LSP-----VT--EGVPLAFSGFPDLVfWRTGGSGGGECSNAALQ--P 1671 Leishmania in...
NP_208263       2 NKVQSIDPLIADKFNnelrsynLEYKL------EQ------------------ESLNKEiDEALKNYASKNGGLGGN--R 55   Helicobacter ...
YP_001436434  140 LLTRDELETLPAPEAg--------DIM------LD-----------------DALDIVLkRNGSFRIPDVIRISDVT--L 186  Enterobacter ...
NP_977342     872 LPPMRYDSVTP------------ERDL------LR----------------HGYNDKVTvFGKLPRRAIQVPKYTGGstT 917  Bacillus cere...
CBH15833      852 DPEE--FPLFDLLQAvp---qgALCAL------LRclylppPE--DGYSVHFDSFPDLVlWREVPS----------Q--P 906  Trypanosoma b...
YP_001059176  143 PDVIIVKN------------------PadrwpgrspvdhegkphvD------NSLRLVEVKFPGD-----KWGVGQEDAY 193  Burkholderia ...
ZP_05588939    77 PDVIVVND------------------P------------------DqppvqsNIKMCAEMKFPPD-----DFSREQRADY 115  Burkholderia ...
YP_202188     133 PDVVTVIDptr------------pptQ------------------D------NLEDVIEIKFPGD-----EMSDAQREDY 171  Xanthomonas o...
ZP_06880302   134 PDVIIVQNpnr------------pptQ------------------D------NIKQVVEMKFPPD-----PHNREQLEDY 172  Pseudomonas a...
NP_928788     139 PDIILVKDevlrwpgrnatyfdgsvhP------------------D------NLKMLIEVKFPGD-----KLSEDQEKDY 189  Photorhabdus ...
XP_001469437 1672 SVGGDSAV------------------L------------------R------TSFRLMEVKGPSD-----FLSTKQIAVN 1704 Leishmania in...
NP_208263      56 PDVKLLLN------------------Tqd--------------pnR------RVPILIEYKGLKDk----LIKLDKNKLV 93   Helicobacter ...
YP_001436434  187 TGNAAFSQ-------------------------------------G------NIHTVIELKFPGD-----RLSPEQEVSY 218  Enterobacter ...
NP_977342     918 PDFIYMIE------------------Kdn---------------dS------SVYVLVETKAENMrledqRIIDIQKKFF 958  Bacillus cere...
CBH15833      907 --DG------------------------------------------------YEFKLVEVLGPNE-----SLSEKQISTI 931  Trypanosoma b...
YP_001059176  194 RRISGMP-----GeytrRMSVIDVSD 214  Burkholderia pseudomallei 668
ZP_05588939   116 IRIAGGP-----N----KFERIGPAE 132  Burkholderia thailandensis E264
YP_202188     172 RRIAGKDpillesseckcskqeqpqk 197  Xanthomonas oryzae pv. oryzae KACC10331
ZP_06880302   173 AAIAGNK-----N----KIVEMKPSD 189  Pseudomonas aeruginosa PAb1
NP_928788     190 IRIATRS----------RFGVMRVDD 205  Photorhabdus luminescens subsp. laumondii TTO1
XP_001469437 1705 DLLHRCG-----F----EVCVVRVDE 1721 Leishmania infantum JPCM5
NP_208263      94 ENFKNHEphyknI----REYALNGAL 115  Helicobacter pylori 26695
YP_001436434  219 RYIAGDR-----E----KFRLLETDV 235  Enterobacter sakazakii ATCC BAA-894
NP_977342     959 DTLKEHHi---------EFIEATSAQ 975  Bacillus cereus ATCC 10987
CBH15833      932 DTLLRCK-----F----DVTVAHVTD 948  Trypanosoma brucei gambiense DAL972
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