Conserved Protein Domain Family
PTZ00481

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PTZ00481: PTZ00481 
Membrane attack complex/ Perforin (MACPF) Superfamily; Provisional
Statistics
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PSSM-Id: 185659
Aligned: 22 rows
Threshold Bit Score: 861.393
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
118395534   1 MCLFVKLKRVDFYYTLGhpqqgflknrsh----fesfydlnlvnESVLNQRQLFQLITSSINEEAKQDLCPYPGFYGDYC 76 
118367559   3 QQKILAFLLIQFILTLShpqqaflknrnhsesfnsqiqdlnlvnESVLNQRQLFQLITSSINEEAKQDLCPYPGFYGDYC 82 
118367563   3 QQKILAFLLIQFILTLShpqqaflknrnhs-esfsqiqdlnlvnESVLNQRQLFQLITSSINEEAKQDLCPYPGFYGDYC 81 
118367567   1 ---------------MShpqqaflknrnhsesfnsqiqylnlvnESVLNQRQLFQLITSSINEEAKQDLCPYPGFYGDYC 65 
118367461   1 ----------------------------------------------------MYKLLSSSNIEEAMQELCPFPGYHGTYC 28 
118367465   1 ----------------------------------------------------MYKLLSSSNIEEAMQELCPFPGYHGTYC 28 
118367469   3 LKKTLICLSIFLILAQC---------------------------QNLNGKRNMYKLLSSSNIEEAMQELCPFPGYHGTYC 55 
118395532   3 QQKVLAFLLIQFILALShpqqgflknrsh----fesfydlnlvnESVLNQRQLFQLITSSINEEAKQDLCPYPGFYGDYC 78 
118395538   1 MCLNVKQMKVDFYYTSShpqqgflknrsh----fesfydlnlvnESVLNQRQLFQLITSSINEEAKQDLCPYPGFYGDYC 76 
118395540   3 PQKVLAFLLIQLIVTLSypqqaflknsnhsesfksqiyepnqvsKSVLNQRQLFQLITSSINKEAKQDLCPYPGFYGDYC 82 
118395534  77 vglqeqqeqfhlhektsmKMLLMSQNSDTEQAVQGIKNMPSGVGVSFDITTGELKLPAIQLTYQNEPTQEQIWKDPLSQN 156
118367559  83 vglqgqqeqlnvykeirmKRQQMSQNSETEQAVQGIQNMPSGVGVSFDITTGELKLPAIQLTYQKEPTQEQIWKDPLSDN 162
118367563  82 vglqgqqeqlnvykeirmKRQQMSQNSETEQAVQGIQNMPSGVGVSFDITTGELKLPAIQLTYQKEPTQEQIWKDPLSDN 161
118367567  66 vglkeqqeqlhlhektsmKMQQMYQNSETEQAVQGIQNMPSGVGVSFDITTGELKLPAIQLTYQKDPTQEQIWKDPFSDN 145
118367461  29 ------------------PQENVAFASYKRNLQSGIPKMPSGIGASFDISTGELKLPAIQLTYQSEPSQEQIYTDPLSSH 90 
118367465  29 ------------------PQENVAFASYKRNLQSGIPKMPSGIGASFDISTGELKLPAIQLTYQSEPSQQQIYTDPLSSH 90 
118367469  56 ------------------PQENVAFASYKRNLQSGIPKMPSGIGASFDISTGELKLPAIQLTYQSEPSQQQIYTDPFSSH 117
118395532  79 vglqaqqeqfhlhektsmKMLQMSQNSDTEQAVQGIKNMPSGVGVSFDITTGELKLPAIQLTYQKEPTQEQIWKDPLSDN 158
118395538  77 vglqaqqeqfhlhkktnmKMLQMSQNSDTEQEVQGIQNMPSGVGVSFDITTGELKLPAIQLTYQKEPTQEQIWKDPLSDN 156
118395540  83 vgiqeqqeslhfhkktsmKMYQASQNSETEQAVQGIQNMPSGVGVSFDITTGELKLPAIQLTYQKDPTQEQIWKDPLSDN 162
118395534 157 QFIIADETQVEQIELQPDIKIFQNEQDLSNLWIEAAQNGYWLGGQYSHSQDLIQIYEKFFKGDQEMSVSQMAKNVLRMTF 236
118367559 163 QFIVADEIQIEQIELQPDIKIFQNEQELSNVWIQAAQNGYWLGGQYSHSQDLNQIFEKFFQGDQEMSVSQMAKNVLRLTF 242
118367563 162 QFIVADEIQIEQIELQPDIKIFQNEQELSNVWIQAAQNGYWLGGQYSHSQDLNQIFEKFFKGDQEMSVSQMTKNVLRLTF 241
118367567 146 QFIVADETQVEQIELQPDIKIFQNEQELSNVWIEAAQNGYWLGGQYSHSQDLNQIFEKFFKGDQEMSVSQMTKNVLRLTF 225
118367461  91 QFIVADETSIEQVNLDADIRVFKNEFELTNIWLDATQNGQWLGGEYSQSKDLNDVFTRFFTNNQQTSIAQQSKNVIRMTF 170
118367465  91 QFIVADETSIEQVNLDADIRVFKNEFELTNIWLDATQNGQWLGGEYSQSKDLNDVFTRFFTNNQYTSIAQQSKNVIRMTF 170
118367469 118 QFIVADETSIEQINLDADIKVFKNEFELTNIWLDATQNGQWLGGEYSQSKDLNDVFTRFFTNNQQTSIAQQSKNVIRMTF 197
118395532 159 QFIVADETQVEQIELQPDIKIFQSDQELSNVWIEAAQNGYWLGGQYSHSQDLNQIYEKFFKGDQEMSVSQMAKNVLRMTF 238
118395538 157 QFIVADETQVEQIELQPDIKIFQNVQELSNVWIEAAQNGYWLGGQYSHSQDLIQIYEKFFKGDQEMSVSQMAKNVLRMTF 236
118395540 163 QFIVADETKVEQIELQPDIKIFQNEQELSNVWVEAIQNGYWLGGQYSHSQDLNQIFEKFFKGDQEMSVSQMAKNVLRMTF 242
118395534 237 KNDNLSLNKYAQRAVNALPQEYSPEVYSDFLESWGTHISVDTYIGGMIEKVNSFKSCVYDSHSFNGGISREQVEQALNNE 316
118367559 243 KSDNLSLNKYAQRAVNALPQEYSPEVYNDFLESWGTHISVDTYIGGMIEKVSAFKSCVNASPSFNGGLSPQQVEQALNNE 322
118367563 242 KNDNLSLNKYAQRAVNALPQEYSPEVYNDFLESWGTHISVDTYIGGMIEKVSAFKSCVNASPSFNGGLSPQQVEQALNNE 321
118367567 226 KNDNLNLNKYAQRAVNALPQEYSPEVYNDFLESWGTHISVDTYIGGMIEKVNAFKSCVNASPSFNGGLSPQQVEQALNNE 305
118367461 171 KTDSLKLNRFAQRAIDALPEDYQVDVYNEFLNAWGTHISVDTFVGGMIEKQTVFKDCIFFTPQFTGGYSAEQVNEALRNE 250
118367465 171 KTDSLKLNRFAQRAIDALPEDYQVDVYNEFLNAWGTHISVDTFVGGMIEKQSVLKDCVFFTPQFTGGFSAEQVNEALRNE 250
118367469 198 KTESLKLNRFAQRAIDALPEDYQVDVYNEFLNAWGTHISIDTFVGGMIEKQTVFKDCIFFTPQFTGGFSAEQVNEALRNE 277
118395532 239 KNDNLSLNKYAQRAVNALPQEYSPEVYSDFLESWGTHISVDTYIGGMIEKVNSFKSCVYDSHSFNGGISREQVEQALNNE 318
118395538 237 KNDNLSLNKYAQRAVNALPQEYSPEVYSDFLESWGTHISVDTYIGGMIEKVNSFKSCVYDSHSFNGGISREQVEQALNNE 316
118395540 243 KNDNLNLNKYAQRAVNALPQEYSAEVYNDFLESWGTHISVDTYIGGMIEKVNAFKSCVYASPSFNGGLSPQQVEQALNNE 322
118395534 317 LNGKPGDNYFVLRRKIDVDHKFGGNPENESNWENTISQNPALLKINKFVSWDSLVTDTQVKQNLQQAIMNRIESMKQRYI 396
118367559 323 LNGNPADGYFAARRKIAVDHRFGGNPENQSNWENTISQNPALLKINKFVSWDSLVADVQVKQNLQQAIMNRIESMKQNYI 402
118367563 322 LNGNQADGYFAARRKIAVDHRFGGNPENQSNWENTISQNPALLKINKFVSWDSLVADAQVKQNLQQAIMNRIESMKQRYI 401
118367567 306 LNGNQADGYFAARRKIVVDHRFGGNPENVSNWENTISQNPALLKINKFVSWDSLVADTQVKQNLQQAIMNRIESMKQRYI 385
118367461 251 LQGNPAEGFFTARRQVTLDHKFGGNPEDVANWEQTISQNPALLKINRFLSWDNMAANPQVKANLQQAINNRVESMRQRQQ 330
118367465 251 LQGNPAEGFFTARRQVTLDHKFGGNPEDVANWEQTISQNPALLKINRFLSWDNMTANPQVKANLQQAINNRIESMRQRQQ 330
118367469 278 LQGNPAEGFFTARRQVTLDHKFGGNPEDVANWEQTISQNPALLKINRFLSWDNMTANPQVKSNLQQAINNRIESMRQRQQ 357
118395532 319 LNGKPGDSYFVMRRKIDVDHKFGGNPENESNWENTISQNPALLKINKFVSWDSLVTDAQVKQNLQQAIMSRIESMKERYI 398
118395538 317 LNGKPGDNYFVLRRKIDVDHKFGGNPENESNWENTISQNPALLKINKFVSWDSLVTDTQVKQNLQQAIMNRIESMKQKYI 396
118395540 323 LIGNPAEGFFTARRKIAVDHRFGGNPENESNWENTISQNPALLKINKFISWDNLVADVQVKQNLQQAIKNRIESMKEIYI 402
118395534 397 NYQQSIQEKRRIESNGPQIAFAVQGYGNTNiilnllygnTNISLPVNYSISNPFQMNEASLCPPELPFDISKSRCSSGEF 476
118367559 403 NNQQSILQQRSIQNNSPKTAYAIQGNGNTNilih-vmvdLHIPAPLNYVVSNPFQMNEASICPPQQPFYLSKINCSSGEF 481
118367563 402 NNQQSILQQRTIEKNSPKTAYAIQGNGNTDvflh-itdkIHLPAPLKYVVSNPFQMKEASICPPQLQLIFSMINCSSGQF 480
118367567 386 NNQQSILQQRSIENNSPKTAYAIQGNGKTDaflh-vaanIHFLAPLKYVVSNPFQMKEASICPPQQQLKFSMINCSSGQF 464
118367461 331 SYQDQVREQRRIERIQPRTAWAIGGNGYCA---------GQHPLPISISITRQFEMKAAGVCPVGADSTYSQTFCVSGPV 401
118367465 331 SYQDQVREQRRIERIQPRTAWAIGGNGYCA---------GQHPLPISISITRQFEMKHADVCPVGIDRHYGETFCVSGPV 401
118367469 358 SYQDQVREQRRIERIQPRTAWAIGGNGYCA---------GQHPLPISISITRQFEMKAAGVCPVGADRTYAEQFCVSGPV 428
118395532 399 KNQQQIQEQRRIESNGPQIAFAVQGYGNTNilih-ilvdTNIPLPLDYAISNPFQMNEASLCPPELPYDISKSRCSSGEF 477
118395538 397 NNQQQIQEQRRIESNGPQIAFAVQGYGNTNiqihlmfgiGNISLPVNYLISNPFQMNEASLCPPELPFDISKSRCSSGEF 476
118395540 403 KNQQSIQEQRKIESNGPKTAYAIQGNGNVStfph-iildLKLSAPLKYEISSPFQMQEASIC---------KSTCSSGEF 472
118395534 477 AEFllLGIPKDVRYERDSLGNFRTILNDS-----------YGNWVNKGCSVASLSRFPQFVDLNQIPPNESRFQMVCTEC 545
118367559 482 ADLqlLGIPKDVRYERDSLGNFRTILNEN-----------YGNWVNKGCSIASVSGFPQFIDLNQIPPNDSRFQIICTDC 550
118367563 481 ADLkiLGLPQDVRYERDSLGNFRTILKET-----------YGNWVNKGCSIASVSGFPEFVDLNQIPPNDSRFQMICTDC 549
118367567 465 ADLqiLGLPQDVRYERDNLGNFRTILKEN-----------YGNWVNKGCSIASVSGFPEFVDLNQIPPNDSRFQMICTDC 533
118367461 402 HSV--QDLRNEVRYERDQEGNYRTIMFDFysggg--pkevYGDFTDRGCSVAQYYEGTKYTDFNLPPPNEMIFKMICTDC 477
118367465 402 HQI--QDLRNEVRYERDQQGNYRTIQYNFfadftggpeelVGEFVDRGCSIAQYYEDTKYTDFNLPPPNETMFKMICTDC 479
118367469 429 HSP--QDLLNEVRYERDQEGNYRTIQYNLfaditggpkelVGDFVDRGCSIAQYYEGTKYTDFNYPPPNETMFKMICTDC 506
118395532 478 TEFflLGIPKDVRYERDSLGNFRTILNDS-----------YGNWVNKGCSVASLSGFPQFADLNQIPPNDSRFQMICTEC 546
118395538 477 TELilFGIPKDVRYERDSLGNFRTILNDS-----------YGNWVNKGCSVASLSGFPQFVDLNQIPPNDSRFQMICTEC 545
118395540 473 ADLsiLGIPKDVRFERDSQGNFRSILNGS-----------YGNWVDKGCSVASLSGFPQFVDFNQIPPNESRFQMICTDC 541
118395534 546 IPNINVSPNGLQLQCN---------------------------------------------------------------- 561
118367559 551 IPNFYNSPNGNILQLNkfqtwlsqsnlplnrftklvlnirhvqinqlekyreqlelkpdtkyfkiikklsdvqlqapynd 630
118367563 550 IPTFYDGPNGNQLQCS---------------------------------------------------------------- 565
118367567 534 IPTFYNGPNGNQLQCN---------------------------------------------------------------- 549
118367461 478 IPSVYNSPQGQVFQCS---------------------------------------------------------------- 493
118367465 480 MPSVYNSPQGQVFQCS---------------------------------------------------------------- 495
118367469 507 MPSVYNSPQGQVFQCS---------------------------------------------------------------- 522
118395532 547 IPNINVSPNGLQLQCN---------------------------------------------------------------- 562
118395538 546 IPNINVSPNGLQLQCD---------------------------------------------------------------- 561
118395540 542 IPSTYNSPNGDLFQCS---------------------------------------------------------------- 557
118395534 562 -------------------------------------------------------CPAF 565
118367559 631 ywlrgvyslsldlndlfqaflkgyqeiyvlkliknvfrmnfkndelslnkysqrgVNAF 689
118367563 566 -------------------------------------------------------CPAF 569
118367567 550 -------------------------------------------------------CPAF 553
118367461 494 -------------------------------------------------------CPAF 497
118367465 496 -------------------------------------------------------CPAF 499
118367469 523 -------------------------------------------------------CPAF 526
118395532 563 -------------------------------------------------------CPAF 566
118395538 562 -------------------------------------------------------CPAF 565
118395540 558 -------------------------------------------------------CPAF 561
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