Conserved Protein Domain Family
SymE_toxin

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pfam08845: SymE_toxin 
Toxin SymE, type I toxin-antitoxin system
SymE (SOS-induced yjiW gene with similarity to MazE ) is an SOS-induced toxin. It inhibits cell growth, decreases protein synthesis and increases RNA degradation. It may play a role in the recycling of RNAs damaged under SOS response-inducing conditions. It is predicted to have an AbrB fold, similar to that of the antitoxin MazE. Its translation is repressed by the antisense RNA SymR, which acts as an antitoxin.
Statistics
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PSSM-Id: 370150
Aligned: 22 rows
Threshold Bit Score: 54.6456
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6D1N5        27 FTANTLfrinlyrnglmltllnedtdiAALMAELDGNeaegadwvsdNGELTLAGDWLTQSGL-PDQPLIIEVLPGRITI 105 Pectobacterium ...
Q8Z0W8        20 NRHLTV---------------------SYASRYPDYTr---------IPALTMKGQWLEAAGFaTGTEVDVRVMNGCIVL 69  Salmonella ente...
Q2SFN5        22 QRRLKVr-------------------kGYYDYHLSSSrydyg-gfkpVPWMLIKGYWLEQAGFgVDTEVEVSVSEGRIVF 81  Hahella chejuen...
Q664Z9        30 FTPGAVfkiqqyrngliitlianeiatQQVFNEIENDhhigmdwiqdNGELSLSGEWLTQTGL-TGQPLAISVMAGKVIV 108 Yersinia pseudo...
Q57SW6        11 SRVERL-------------------------------------------SVRLYGEWMPQAGFiNGMPVKVRVMRDCIVI 47  Salmonella ente...
Q7N1T9        16 ERFGKVa----------------------------------------KNGISLKGKWLQEAGFtFGMPLKIRVMPDCIVI 55  Photorhabdus la...
Q6D1M7        19 ERFTRV---------------------GYRPIKGNHA----------TPAINIAGQWLKDAGFtTGQPLRLRIMPGCIVI 67  Pectobacterium ...
Q6DA58        11 ALLHLI---------------------SYVSRRHADRsdmtr-yysrSPSLHLQDHWLEAAGFeIDIPVVITVEQGQLVI 68  Pectobacterium ...
Q7M779        16 RRSYKV---------------------GYARTRHEDRstgmtryysqHPSLHLKGNWLEEAGFaTGQPVQVSVEHGQLII 74  Photorhabdus la...
WP_000807562  16 QRRYKV---------------------GYVRARHQDRktgiaryysqHPSLHLKGDWLKEAGFdTGRGVTVKISEGGLTI 74  Enterobacteriaceae
Q6D1N5       106 RA 107 Pectobacterium atrosepticum
Q8Z0W8        70 TA 71  Salmonella enterica subsp. enterica serovar Typhi
Q2SFN5        82 TA 83  Hahella chejuensis KCTC 2396
Q664Z9       109 RG 110 Yersinia pseudotuberculosis
Q57SW6        48 TP 49  Salmonella enterica
Q7N1T9        56 TA 57  Photorhabdus laumondii subsp. laumondii
Q6D1M7        68 TT 69  Pectobacterium atrosepticum
Q6DA58        69 RP 70  Pectobacterium atrosepticum
Q7M779        75 RL 76  Photorhabdus laumondii subsp. laumondii
WP_000807562  75 IA 76  Enterobacteriaceae
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