Conserved Protein Domain Family
LhgO

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COG0579: LhgO 
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism]
Statistics
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PSSM-Id: 440344
Aligned: 715 rows
Threshold Bit Score: 134.888
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_081469475  23 NPPIDFVLIGCGVMSATLGIYLK-LLepS-WIIHAYERLDKVGQ--ESSHgwNNAGTGHSafceLNYTSiqknGK--VDI 96 
ABX12305       2 AKNFDVVIIGGGILGTSISYFLS-HLnkS-KKVAVIEQAKNVAF--HTSG--RNTGKVHAp---YLYNP----EKkkLFA 68 
ABK76953      21 TKRFDVVIVGAGILGTSIAYFLG-HLnpS-REIAVVEQALRVAF--HTSG--RNTGKVHAp---YLYDP----KKkaLTA 87 
AFU60328       1 -MDCKVAIIGGGVLGTSIAYFLSaHArdP-GSVALIEQEKNIAQ--HTSS--RNTGKVHAp---FLYDP----AKkkTFA 67 
CUR51127      20 LEKFDVAIIGGGLLGTSISYWLS-SLy-D-IKIAVVEKEQDVGM--HTSS--RNTGVVHSp---FYLNP----EKkaKLA 85 
NP_206886      2 SMEFDAVIIGGGVSGCATFYTLS-EYs-SlKRVAIVEKCSKLAQisSSAK--ANSQTIHDg---SIETN----YTp-EKA 69 
WP_084790704   1 --MYSVAVIGGGILGTSIAYFLSgQArdP-GSVALVEQELDIAR--HTSS--RNTGKVHAp---FLYDP----AKkkLFA 66 
WP_048105797   1 MKKFDIAILGGGILGTTISYWIS-NLy-D-SSVCVIEKESNVAQ--HTSG--RNTGVVHTp---FYLNP----EKkkIFA 66 
WP_086907968   2 KDYFDLVIIGGGILGTSISYFLS-FLnkS-KKIGVIEQENNVAH--HTSG--RNTGKVHAp---YLYNP----EKkkLFA 68 
WP_130538122   3 NRNLDVAIVGGGISGSALAYMLS-KYs-DvKTIGILEKYETLSPlnSNAR--ANSQTLHCg---DIETN----YTl-EKA 70 
WP_081469475  97 SKAISVNESF-EISKQLwaylvkkeILKnpntfinTVPHISFVWGENNIKFLKSRFHALKNNvLf-kGMLYSeDYNTIKK 174
ABX12305      69 NAAFHGFDMWeEYSKLH--------NLPf-----kKDGVIEVALDKKGIKVLEKYLKWAKQNgLeekDIELM-DKSEIKK 134
ABK76953      88 RASFHGYAMWeEYSKNR--------GLPf-----kRDGVVEVAMDADATGVLDRHLQWGMENgLgedEIMLL-DRAEMEK 153
AFU60328      68 KAAFLGYEMWqKYSDYK--------GLPf-----kRDGVLEVALDEKGIDRLQKYMEWGEANgLgksELQLL-DKNEAAK 133
CUR51127      86 KAAFLSHAMWkTFAEKR--------GLPw-----nVVGTIEVALDETQHKILEKYMAWGPKNgMsenDITLL-DGTEVTK 151
NP_206886     70 KKVRLSAYKTrQYALNK--------GLQnev--ifETQKMAIGVGDEECEFMKKRYESf-KEiFv--GLEEF-DKQKIKE 135
WP_084790704  67 KAASLGFEMWeKFAQAR--------GLPf-----eRDGVLEVATDERSIDRLHKYMSWGEANgLakdDLLLL-DKAGTKK 132
WP_048105797  67 KSAQSSHELWkTLAENT--------MSPw-----nEIGTIEVALNETQHKTLEKYQKWGIENgVleeNLVLL-DSNEIKQ 132
WP_086907968  69 NAAFHGYEMWkEYSKQQ--------NVSf-----kEDGVIEVALDEKGIKVLEKYLKWGKQNgLqekDIELI-EKAELKK 134
WP_130538122  71 KLVKKQANMVvHFADQV---------EKndf--lyKFPKMILAVGDEECERLEKRHHDf-AEdFp--YMELW-DADKIAE 135
WP_081469475 175 WAPLVmYkr----nlTQKVAATYMSIGT-DVNFGEITRQIFLYLNNh-SNf--HLHVNHDVINIKQNRdKtWKIH-Ilyk 245
ABX12305     135 IEPEI-K----------CEAALYVYRDG-SADYSTYTESLMKDSKE--NGt--AFLLDTKVTETKRENgK-WKITlN--- 194
ABK76953     154 REPNV-K----------CEAAIYCGRDA-SVDYAAFTRALGGDTTA--AGv--RFLLNTRATGISRIDdG-WNVTlD--- 213
AFU60328     134 MEPNV-R----------CASAIYCSKDA-SVNYGALALALMEDIQS--FGc--KLLLGHRAARISYNQgA-YSITtN--- 193
CUR51127     152 KEPNI-Q----------CHSAIHCKTDA-VVDYGIYTRKLKEESQR--NGt--KFLLGHKLESVENPDdC-PVLGfA--- 211
NP_206886    136 LEPNV-IlgangidrHENIIGHGYRKDWsTMNFAKLSENFVEEALKlkPNn--QVFLNFKVKKIEKRNdT-YAVI-Se-- 208
WP_084790704 133 MEPNV-R----------CEAAIYCGKDG-SVDYGSFSCTLLQDLRS--FGc--AVLLGHGVTRVENKAgA-YVIStR--- 192
WP_048105797 133 KEKNV-E----------CFSGLLCKSDV-STDYSKLTQEIKKISVQ--NSt--EFLFQKSVKSFIKNDdA-IQVNfT--- 192
WP_086907968 135 IEPEI-K----------CEAALYAHRDG-STDYSTLTNAIMRDSKK--NGi--NFLFNNKTNEIKKNKdK-WEITiN--- 194
WP_130538122 136 VEPAV-Alkdg-kprPEKILASGCTNEYsAVNYGNMSKALIAEARK--GSanlKVSLSTKVQNIRKTVeG-YELD-T--- 206
WP_081469475 246 DlinkTKkliYIDTKYVFIGSGGNALRLLQKSGIqesHKYAGFPVGGQFLVTkNk--ILTNqhyAKVYGKA-PIGAPPMS 322
ABX12305     195 E----ED---EIFTEFLINAAGGEAVDIAHDVGVa--TELTDVHFRGEYWKApKqynNLTK---TSIYSVPeFPDYPFLD 262
ABK76953     214 G----EH---EVEAGLLINAAGGEAVDLAHAAGVa--KDLTDVHFRGEYWRApAeysGLTH---SSVYSVPaRPEYPFLD 281
AFU60328     194 Q----GE---QVRADYLVNAAGGNSMDIAHMMGVa--QGYTDLHFRGEYWQApSqyhDLTK---LSIYSVPkHPEYSFLD 261
CUR51127     212 N----KE---KISSKLVINCAGGYSLDVAKKFSLa--MQYSSLHFRGEYWIArEqytNLVK---TNVYSVPnYPDFPFLD 279
NP_206886    209 D----AE---EVYAKFVLVNAGSYALPLAQSMGYg--LDLGCLPVAGSFYFVpD----LLR---GKVYTVQ-NPKLPFAA 271
WP_084790704 193 Q----GR---KIEAEFIVNAAGGNAVDIAHSMGVa--REYTDLHFRGEYWQApEqyrDLTR---LSVYSVPrHTEYPFLD 260
WP_048105797 193 D----NS---SIECSYLINCSGGNSLDIAKQFDLf--ESYSDLHFRGEYWIAhNsyaDIVK---TNIYSVArHPEFPFLD 260
WP_086907968 195 G----NH---KIYADFLINAAGGQAIDIAHNIGIa--KNLTDVHFRGEYWKTpKkyhNLTK---TSVYSVPeFPEYPFLD 262
WP_130538122 207 N----QG---TFKAKFVVVSAGGHSLLLANQVGYg--LDMSILPMAGSFYYVpK----MLN---GKVYTMQ-NDKLPFAA 269
WP_081469475 323 VpHIdTRILDgeKVLLFGPFATFSSKflKNgswtdlfcsltyknifp------------ivqvgiknislvqyligQLLT 390
ABX12305     263 P-HW-IIRVD--GNCEIGPNAVPVFS--PYgynkaenikefvpkmlemlg------sgarkaifdkqfqelamneiQSSM 330
ABK76953     282 P-HW-IVRSD--GTCEVGPNAVPVFS--PYgytgrenarrlvpkmfemls------sgarkmvfdrqfqklalgevRSSL 349
AFU60328     262 P-HW-IVRAD--GRREVGPNAVPVFG--PYaytwrkniadmlpkiiessr------tgarkivfdrqfmslastelKSSL 329
CUR51127     280 P-HW-IIRSD--GKSEVGPNAVPVAS--PEiysgyvgdietfiskladvvt-----gstrklllnpefmnliakewLSSL 348
NP_206886    272 V-HG-DPDAVikGKTRIGPTALTMPK--LErnkcwlkgislellkmdlnkdvfkiafdlmsdkeirnyvfknmvfeLPII 347
WP_084790704 261 P-HW-IVRAD--GRREVGPNAVPVFG--PYayslgrniadmlpkiiessa------tgarkvffdrqflslastelKSSL 328
WP_048105797 261 P-HW-IKRAN--GTTEIGPNAVPVPT--PEtydgfvtdipstisklgeilt-----ggakklflnpdfislishefRSSI 329
WP_086907968 263 P-HW-IVRVD--GSCEIGPNAVPVFS--PYgynttenikqfipkilemin------sgarkiifdkdfqelafseiQSSM 330
WP_130538122 270 L-HG-DPDLVelSKTRIGPTALVLPK--LErytggtyldfwkslkldrkvik--vfwdlmkdktirnyifrnfafeIPWL 343
WP_081469475 391 SKKGKFITLCKYFPNAnikDWH-LI-TAGQRVQIikndpnqggtlqfgTEIVHSSD-----KTLSALLGASPGASTSAAT 463
ABX12305     331 SKSTMVERVRRFLPKIdaeKITeKG-TAGIRSSIinekg-----kfepDVILLDDEs-----SFHILNYNSPGATGALPF 399
ABK76953     350 SKSAMIGRVQSFLPGIdpgRFTeRG-SAGIRSSVvdsgg-----hfvpDAVLAPGHs-----SFHILNYNSPGATGALPF 418
AFU60328     330 SKTAMINRVREFLPQLrpsAFTqRG-TAGIRSSVidktg-----rfvpDTLVLERDs-----SLHVLNYNSPGATGALPM 398
CUR51127     349 SKVVMIERVQKFMPKIkpdFFSeRG-TAGIRTPIitpeg-----qflpDVLELEGKa-----SYHILNYNSPGATGAPAY 417
NP_206886    348 GKRKFLKDAQKIIPSLsleDLEyAHgFGEVRPQVldr--------tkrKLELGEKKic-thKGITFNMTPSPGATSCLQN 418
WP_084790704 329 SKTAMINRVREFLPALrpsAFTeRG-TAGIRSSVidreg-----rfvpDTLILKRDs-----SVHVLNYNSPGATGALPM 397
WP_048105797 330 SKDAMVQRVMNFIPSLkpdYFTkKG-TAGIRTPVispdg-----nfisDVMEREGHn-----SFHIVNYNSPGATGAPAY 398
WP_086907968 331 SKSVMVERVKKFLPKInskEITeKG-TAGIRSSVideng-----kfvpDVILVEEDt-----SFHILNYNSPGATGALPF 399
WP_130538122 344 RRRLFAKDVQKFLPDVkpqDLEyASgIGGLRPQVidk--------ttmQLKLGEASivpenENLIFNMTPSPGATTCLGN 415
WP_081469475 464 MLDLLKImFKEKIn---HN 479
ABX12305     400 AAHVVNH-LHNsglllsET 417
ABK76953     419 AAHIVGR-LGAegllknEM 436
AFU60328     399 AADVASK-VMEagvlqtDS 416
CUR51127     418 SAYVVKA-LREkgflqyAA 435
NP_206886    419 ALVDSQE-IAAYLge-sFE 435
WP_084790704 398 AAKVAAQ-VMEagalaqAG 415
WP_048105797 399 SALIIKK-LQDkgilkkPN 416
WP_086907968 400 SVHVINQ-LHQkglfenDD 417
WP_130538122 416 AYRDAKI-VCERLgv-pIK 432
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