4TQT


Conserved Protein Domain Family
AllB

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COG0044: AllB 
Dihydroorotase or related cyclic amidohydrolase [Nucleotide transport and metabolism]
Dihydroorotase or related cyclic amidohydrolase is part of the Pathway/BioSystem: Pyrimidine biosynthesis
Statistics
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PSSM-Id: 439814
Aligned: 832 rows
Threshold Bit Score: 203.014
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4TQT_A        17 VIKGGTVITADR-T-FRADILIEDGKIAAI--------GDSL-------EGDEVIDASGC-YVMPGGIDPHTHLQMPfmg 78 
WP_012875314   5 LLSGARIVCPYTsIdSTGDVLIEDGRVAAVc------iGKSLd-----vDQAESVDCKGL-VLSPAFVDVHVHLREPge- 71 
WP_025439294   5 LFENVRLIDPATaLdRPGRLLVQDGVIAGT--------DLPqae--gipEGAEVIDGGGQlVLCPGLVDMRVTIGEPgy- 73 
WP_011451558  15 AFVDARIVDPESgLeILGDLVVHGRRIGDF--------GESLlsdvelkSFDEVVNCDGH-ILMPGIIDIHVHLRDPgq- 84 
WP_114911955   9 LFRNVRLVDPASgRdGAGELLVRRGVIADI--------AEtla----tsEGAEIIDGGGA-VLCPGLVDMRAALGEPgf- 74 
WP_012812670   5 LFENVRLIDPASgLdQPGRLLVRDGVIAGT--------DKAgte--gtpENATVIDGKNA-VLCPGLVDMRVEIGEPgy- 72 
ABX06732       5 VIKNGCIIDPARkTaTVGDLVLENNRVREViel---amAPDsy-----gDDVEFIDASGC-FVTPGFIDIHTHLREPgf- 74 
WP_011631514  10 LLTHVRLLDPQSgLdQPGSLLVRDGRIADF--------GPslg----rpDGVEEIDGDGC-VLCPGLVDIRVGLGEPgh- 75 
WP_011957574   4 LIKNGSIIDPARrVaTIGNVLVENGKVVQVidladltiAPEPl-----dDHTEVINARGA-VIAPGFLDLHAHVREPge- 76 
WP_014746062  21 AYVNARLIDPATgTdRIGTLLTEGETIVDI--------GAGLfad-gvpEGVQVVDCTGL-VLAPGLVDMHVHLREPgh- 89 
4TQT_A        79 tySSDDFDTGTAAALAGGTTMVVDFVLPDSEGNLLDALQEWFQKA-GKARTDYSFHMAITGWn-eRTFNEMAEVVKRGIN 156
WP_012875314  72 -eHKETIASGASAALAGGFTTICAMPNTNPAIDNSRLVRWVIDRAnGTG-IRVLPIGAITIArqgKVPVDYEAMVKAGAV 149
WP_025439294  74 -eYRETVLSAAKAAVAGGITTIAVLPNTSPTIDNPALARLLRARGeETGMIDILPYGALTREcagTEMAEIGLLAEAGAI 152
WP_011451558  85 -lQNEDIHSGTKSAAAGGVTTVVCQPNTDPPIDTVETLAYIRDKAkRVGFVNVLCYASITgr--gGDLTDMFALHKAGAV 161
WP_114911955  75 -eYRETIASAAAAASAGGITTLAVLPDSDPAIDDPALVHFLRARGeATGRLTILPYGAVTRGcrgEELAELGLLREAGAV 153
WP_012812670  73 -eYRETVSSAARAASAGGITTLAVLPTCKPAIDNPALVRMLRTRGeETGAITILPYGALTKGcegKELAEIGLLHEAGAV 151
ABX06732      75 -eGKETIATGMDAAVRGGYTTICPMPNTNPSLDSAPLIRQQFDIAaRHGPIHVLPIGAVTLGregKVLAPLVELAEAGAH 153
WP_011631514  76 -eYRETIASTAQAAAAGGITTIITLPDTRPSIDDPALVHLLRSRGeETGSLSILPYGAVTRGcrgEELAELGLLHEAGAV 154
WP_011957574  77 -eHKETIETATKAAAAGGFTTLCVMPDTRPPIDCAAVARQIRDIArRRGVVRIEPIGAITVGragQTLTEMAELVEAGCV 155
WP_014746062  90 -eHKETIETGSRASAAGGVTTIACMANTAPVIDDIALVDFIRRRArETGLVNVLPVAAITKGlkgEQLVEMGLLAEAGAA 168
4TQT_A       157 TFxhfmaYK-GALMVNDDEMFASFQRCAELGAMPLVHAENGDIVaQLQaklMAEGNDGPEAHAYSRPPEVEGEATNRAIM 235
WP_012875314 150 AF-----SDdGSPVMNSRMMRLALLYSRTLGVPISSHCEDTELSaKGC---MHDGAVSARLGLPGIPASAEEAMIYRDLS 221
WP_025439294 153 AF-----TDgPHAIADSRTMRQMLTYARGFDALIVQHPEDPSLArGGC---ATDGELATRLGLPGIPAAAEAILIARDLR 224
WP_011451558 162 GF-----TDdGLPVMNSLFMRQAFMNAALLKVPVAQHAEDLDLSnGGC---INEGAISHKLNVPGISHLAESVMVARDVL 233
WP_114911955 154 AF-----SDgARTIHPARLMRLALAYARGFGARIVQHPEEPSLAaGGA---ATEGELATRLGLPGIPACAEAIQVARDLR 225
WP_012812670 152 AF-----TDgARALDPARLMRLALSYASGFGAMIVQHPEEPSLAgSGC---ATAGALATRLGLPGIPAAAEAIMIARDIR 223
ABX06732     154 GF-----SDdGSPVWDAHIMRQALLYSKMTGRPVMNHCEDLSIVrGAP---MNEGAVATRLGLSGWPAAGEEVMIARDIA 225
WP_011631514 155 AF-----TDgTSAIASARMMRLALSYARGFGAKIVQHPEDPSLAaGGA---ATEGELATRLGLPGISPAAEAIMIARDIR 226
WP_011957574 156 GF-----SDeGNTVMDATVMRNALAYAAMLDTPIMAHCEDVRLTrGWG---MHDGAVGIRLGLPGYPAAAEEAMVARDIA 227
WP_014746062 169 YF-----SDdGLPVRDTLVMRRALSYAGGMGLLVAQHAEDHSLAgCGC---MNEGETATRLGLPGIPSAAETVIVERDIR 240
4TQT_A       236 IADQAG--VPLYVVHVSCEQSHEAIRRARQKGMRVFGEPLIQHLTLDESEY----------------------------- 284
WP_012875314 222 LAAETG--GHIHIAHVSTSGGVEAIRHAKKIGVRVTAEATPHHFTFTDEWVagwrdss---------------------- 277
WP_025439294 225 LARMTG--GRLHFGHVSTAEGLDLIRAAKADGIRVSCDTAPPYFDLNETVI----------------------------- 273
WP_011451558 234 LLEQLG--AHYHVLHVSTKKTVEIVRAAKDKGMRVTCEVTPHHLLLTEEAV----------------------------- 282
WP_114911955 226 LAELTG--GMVHFSRLSTAEALALVRAAKARGIAVTCDTAPPYFALNELAI----------------------------- 274
WP_012812670 224 LAELTG--GRLHFAHVSTGEGVALIRQAKERGLNVTCDTAPPYFDLNENTI----------------------------- 272
ABX06732     226 LAEETG--GRLHICHVSTAGGVELIRAAKARGVRVTGEVTPHHLTMTDRWVlgsmepwdg-------------------- 283
WP_011631514 227 LAALTG--GSVHFGHVSTAEAVSLIRRAKNEGINVTCDTAPPYFDLNETAI----------------------------- 275
WP_011957574 228 LAEMTG--AHLHICHVSTAGSVALIRAAKARGVRVTAEVTPHHLTLTDRWVlgnldvphgegksghragrervdanedgl 305
WP_014746062 241 LLELTGgkARYHVAHISTAEAVEAVRQAKRRGLPVTAEVTPHHFTLDDRAV----------------------------- 291
4TQT_A       285 -----------HnrdwdyAARRVMSPPFRDKLNQDSLWAGLAAGSLQCVATDHCAFTTEQKRygiGNFTKIPNGTGGLEE 353
WP_012875314 278 ----tdrclsiSa----yDTNAKVNPPLRSREHVEAVIDGLVDGTIDAIATDHAPHSVLEKD---CPFEEAAFGISGLET 346
WP_025439294 274 -----------Gd----fRTYAKLSPPLRAEADRRAVCAALADGTIDAIASDHMPCDADDKR---QPFAVAAAGGTGLCT 335
WP_011451558 283 -----------Dg----yNTAAKMNPPLRTEEDRLCMIEALKDGTIDAIASDHAPHNEVYKE---LPLKEAAFGVVGLET 344
WP_114911955 275 -----------Gd----fRTYAKLSPPLRAEADRQAVAAALADGTIDAVVSDHQPRDADDKR---LPFAEAAPGGAGLAT 336
WP_012812670 273 -----------Gd----fRTYAKFSPPLRSEDDRLAICAALADGTIDAIGSDHLPRDADDKR---LPFAQAATGGAGLVT 334
ABX06732     284 --kgpydpsqlAp----yDTRTRVSPPLRTSEDVAALIAGLRDGTIDAVATDHAPHTHVDKE---CEYGFASPGFTGLEL 354
WP_011631514 276 -----------Ge----wRSYAKLSPPLRAEQDRLAIAAGLKDGTIDAIASDHQPRDADDKR---VPFAQASPGGVGLVT 337
WP_011957574 306 dlpsrlkstllPp----yHTSTRVRPPLRTEQDVEALIEGLRDGTIDAIASDHEPQSAVDKE---CEYRLAASGISSLET 378
WP_014746062 292 -----------Gd----yRTFAKMAPPLRAARDVDAMIEGLADGTIDAVATDHAPHDQDSKR---VPFAHAANGVVGLET 353
4TQT_A       354 RMPVLWTRGvRTGRLTPNEFVAVTSTNIAKILNIyPqKGAVVPGADADLVIWDPETTKKISAKTQHSSIDYNVFEGFELK 433
WP_012875314 347 ALPLSL-ELvRTGRISMMKMVSLLTISPAKAFGI-D-HWGIEEGRDANLVLFDPNLKWTVTPSALLSKGKNTPLIGRQVM 423
WP_025439294 336 LLAVTL-AQvHAGNIGMMDALGLLTHRPASVLRS-G-AGTLGAGKPADLCLFNPDTGWIVRAGELPGKAQNTPFDGRALE 412
WP_011451558 345 ILPLSL-ELyHSGALELHSLLAKLTCNPAKIIGS-E-AGRIKVGAPADLVLLDLNSEVRIETRQFVSKSKNSPFGGRKTR 421
WP_114911955 337 LLAVTL-AEyHGGRLTLSRVIELLTIAPARLLGV-A-AGRLEKGLAADLCLFAPERAFRVTAGALPGKAQNTPFDGRALE 413
WP_012812670 335 LLGVTL-ARvHDGTLTLPQALSLLTHRPAQLLGA-E-CGTLAVGAAADLCLFDPEQSWLVEAGKLPGRAQNTPFDGRPLE 411
ABX06732     355 ALPMVLT-LvQTMQIDIVELISRMTIGPAAIIDV-L-PISLGPNDPATLTIFDPAAIWKVTPEALASKGKNSPLMGQEMR 431
WP_011631514 338 LLGITL-AQvHGNGLPLSQAIAMLTSRPAGLFGL-E-AGTLRQGAPADLCLFHPERAWQVEAGKMPGKAQNTPFDGRPLE 414
WP_011957574 379 ALGLAL-TLvHRGKLDLVDLVAKFTEGPATVLGR-A-PATLRPGSPADIVIFDPDSPWIVDPARFFSKGRNTPLAGQRLK 455
WP_014746062 354 MLPLTL-ELvRDGHMSLIDAVAAMTLKPADLLGI-A-AGRLAKGAPADLVLFSTEHEWVLNAALLHSKSKNTPFDGRTLR 430
4TQT_A       434 GLPIMTLSRGRIAFDK 449
WP_012875314 424 GRVLMTISGNKRYVRE 439
WP_025439294 413 GRVLGTWKNGRRVFGA 428
WP_011451558 422 GKVLRTIVGGDTVYMD 437
WP_114911955 414 GRVLGTWKAGRRVFG- 428
WP_012812670 412 GRVLGTWKAGRRVYEA 427
ABX06732     432 GQVMLTMMEGQIVYRR 447
WP_011631514 415 GRVIGTWKAGRRVFG- 429
WP_011957574 456 GQVMLTMYRGQIVFRR 471
WP_014746062 431 GRALRTVVRGRTVFQL 446
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