6HUM,6Z16,6TJV


Conserved Protein Domain Family
NuoL

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COG1009: NuoL 
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase
Statistics
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PSSM-Id: 440633
Aligned: 716 rows
Threshold Bit Score: 248.914
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6HUM_F         5 YQYAWLIPVLPLLGALIVGFG---------L-IAf-SettsklRRPSAIFIMALMAIAMGHSLTLFWsQVQ-GHl----P 68 
WP_013157738   1 --MLVLTILFPLLGFVLLGLL---------G-KRm-R------EPLPGVIASGLVLASLVLGVALLA-Q---GG-----A 52 
WP_012683140   3 AALLPFLILLPLLGFVVNGAValsrasaadGaRStaR------HPLVSIVGPGVIIAAFAVAMALFM-RMRvGMag--pA 73 
WP_013457332   1 -mLLLLILLLPLLGFVFLGLF---------G-KHl-R------EPAPGVIASALTGLSFLLVL---Y-GVLtGG-----A 53 
WP_015797843   1 MDLITAVIGFPLLGFLVLLAF---------G-KRi-G------EPRAGWVGTIATTLSFVAALALWG-VVLaRPadervA 62 
BAN00731       2 TELVWLIPAFPLLGFLLILVG---------G-RKl-G------EPKAGLLATTMVAASFVVAVAIFF-DLLgMSaeersH 63 
WP_013179429  16 TSLAAGAPFFALLGAFVCGFF---------G-RYl-R------GTAPGVFATSMVGIGFFLSLAAFF-SLLfRae--rtV 75 
NP_295217      2 LMPLYLLPLLPLLGFALLMLF---------P-RAf-P------GKSGSWLATVMVLLSFAVAVMRYL-G---Qgd--taA 58 
WP_014432147   2 FDLAWLLFAFPALSALIILFA---------G-RWm-S------QKVVGWIASLAVVGSFAVSAMLWV-GLLaLPaeersV 63 
WP_012616316   2 ELLIWLIPLLPFIGFLLNVFV---------I-RRe---------REAGLVASGMVAAAFVVTLIAVG-MLAgMPpeerrI 61 
6HUM_F        69 YTQMIEWAaagnLH--IAMGYVIDPLAALMLVIVTTVAFLVMLYSDGYMAHDPGYVRFFAYLSLFGSSMLGLVVSPNLVQ 146
WP_013157738  53 KFAVPDWLp------gISFSLNLDHLSGLMLLIVTGVGFLIHVYAIGYMAGDAGFSRFFAYLNLFIAMMLTLVLADNYVV 126
WP_012683140  74 IVSLGQWMpvgnLV--IDWNFQLDQLSMLMVLVITGVGSLIHLFSIGYMQDDPGYARYFAYLNLFVAFMLVLVLGGSYPV 151
WP_013457332  54 EWAIKDWLp------gIPFSLVLDSLSGYMGLVVTGIGFLIHVYAIGYMHGDAGFSRFFAYLNFFIAMMMTLVLAGSYPV 127
WP_015797843  63 VVRLFTWFragpLV--AHISFRVDELTVFMVLFVTGVSSLIHLYSIGYMHRDPRFHQFFVYLNLFVFSMTVLVSSNNLPL 140
BAN00731      64 TETLFSWVpvgdLQ--IDMAFLVDPLSITMCLFVTGIGALIHLYSIGYMHGDPKFSKFFLYLNLFILSMTLLVLGSNLLV 141
WP_013179429  76 HVPLWSFLqagdFR--LDLGFVLDPLSVTLMLIITGVGFLIHLYSIGYMHGDEGFARYFAGLNLFVASMLVLVMADSFLL 153
NP_295217     59 HETLWPWLpnmaLNanLSVGFYLDRLSSLMTLIITGIGFLIHVYSVSYMAHDAKFTRFFAFLNFFVSMMLILVLADSYPL 138
WP_014432147  64 TVHWWDWItiadFH--APAAVLLDPLSLVMAMVVTGVGALIHIYSIGYMDHEPRYQRYFFYLNFFILAMLTLVMSNNFLG 141
WP_012616316  62 VSTAWEWIstgsFR--VPFAVMFDPLTAVMALLITGVGALIHVYSIGYMHGDPRVVRYFAYLNLFVTMMLFLVMANNLLL 139
6HUM_F       147 VYIFWELVGMCSYLLIGFWY------------------DRKS-----AAEAAQKAFVTNRVGDFGLLLGMVGLFWATGTF 203
WP_013157738 127 MFIGWEGVGLASYLLIGFWY------------------QDRV-----NADSARKAFIVNRIGDLGFLLGMGLLWAMFGTL 183
WP_012683140 152 MFVGWEGVGLASYLLIGFWF------------------SDKA-----NADAGKKAFVVNRVGDFGFLVAMFLIWVTTQHL 208
WP_013457332 128 MFIGWEGVGLASFLLIGFWY------------------TEKV-----NADSARKAFITNRIGDLGFLLGMALLYSLFGTL 184
WP_015797843 141 TFLGWEGVGACSYWLISFWF------------------ERPS-----AASAGKKAFIVNRIGDAGFILGTALIVDHLHSV 197
BAN00731     142 TFLGWEGVGTCSYFLISFWH------------------TKDA-----NATAGKKAFVTNRIGDFGVMLAMFLAFGAVGSI 198
WP_013179429 154 MFLGWEGVGVCSFLLIGFWY------------------RDRL-----NADAARKAFITNRVGDVGFLLAMFLTFQTFGTL 210
NP_295217    139 MFVGWEGVGVASFLLIGFWHsgrnseasdkdvrdastsEGRA-----NSNAARKAFIMNRIGDLGFMLGMFLLYKLYGTL 213
WP_014432147 142 MFVGWEGVGLASFLLIGFWF------------------DKRDdlygwYADCGKKAFIVNRVGDFGMILAMIMVWSTLGTV 203
WP_012616316 140 LFLGWEGVGLCSFLLIGFWF------------------ERKS-----ASEAAVKAFVVNRIGDAAFILAMLAIFAYFGTL 196
6HUM_F       204 DFAG------M-G-DRLTElvn--tglL--SPSLAAILAILVFLGPVAKSAQFPLHVWLPDAMEGPTPISALIHAATMVA 271
WP_013157738 184 GISE------I-N-TKLEEn------lF--IPAGLSLAAFLLFVGAIGKSAQVPLMVWLPDAMAGPTPVSALIHAATMVT 247
WP_012683140 209 DFVG------A-H-SVLGGm---------gGTPVVLAIALFLFVGCAGKSAQLPLYIWLPDAMAGPTPVSALIHAATMVT 271
WP_013457332 185 SIGE------L-R-EAIEGs------tV--LPMALGTAGLLLFVGAVGKSAQVPLMVWLPDAMAGPTPVSALIHAATMVT 248
WP_015797843 198 SYSV------I-L-PEAHR--------L--SSGTLEAVALLFFLAAVGKSAQLPLFVWLLDAMEGPTPVSALIHAATMVT 259
BAN00731     199 DYAV------I-N-DSALAg------tL--TQATATGIAALLFLGAVGKSAQLPLYVWLPDAMAGPTPVSALIHAATMVT 262
WP_013179429 211 EIAA------V-N-EAAGGl------vA--GSAVLTTLGLLYLIAACGKSAQLPLHVWLPDAMAGPTPVSALIHAATMVT 274
NP_295217    214 SIPE------L-A-GQAAGt------rV--AQSAIELACLFLLVGAVGKSGQLPLTTWLPDAMAGPTPVSALIHAATMVT 277
WP_014432147 204 VFTE------L-S-EAAHH--------L--APATATIICLLLLLGATGKSAQIPLYVWLPDAMAGPTPVSALIHAATMVT 265
WP_012616316 197 NFYGdgesgqLgFlERVGDiaglkigpTwqPVFLSTVISFLLLIGATGKSAQFPLFVWLPDAMAGPTPVSALIHAATMVT 276
6HUM_F       272 AGVFLIARMFPVFEQLPQ-VMTTIAWTGAFTAFMGATIAITQNDIKKSLAYSTISQLGYMVMGMGVGAYSAGLFHLMTHA 350
WP_013157738 248 AGVYLLARSSFLYINVPE-VSLWIAILGLATAIYGALSAFGQQDIKRIVAYSTLSQLGFMFVAAGMGAYWIALFHVLTHA 326
WP_012683140 272 AGVYLVARAAPIFAGAPE-ASLVITAIGALTALFAATIALRQWDIKKVLAYSTVSQLGYMFVAVGSGAYTAGVFHLVTHA 350
WP_013457332 249 AGVYLIARSSFLYANLQD-VSYFIAVIGLVTAAYGALSALGQWDIKKIVAYSTISQLGYMFLAVGVGAYWIALFHVMTHA 327
WP_015797843 260 AGVFLMARLSAFVTPAHD-AATVIAWIGAITAFVAAMAATSQHDIKKIVAYSTVSQLGYMMLGIGTGAYVAALFLMVTHA 338
BAN00731     263 AGVFLMVRINPVLGAAADwVPMLIAWVGALTALFAASIALAQNDIKKVLAYSTVSQLGYMFLAVGTGAYVAAIFHMITHA 342
WP_013179429 275 AGVYLVARAAPLFAAAPA-ASAAVAWVGALTALFAAFAALSQLDIKKILAYSTISQLGFMFVAVGVGAYWVGIFHVLTHA 353
NP_295217    278 AGVYLVTRSHFLYELAPV-ASNWVAWVGGLTALYGALSALNQHDIKKILAYSTVSQLGYMFMAVGLGAYSAGVFHLLTHA 356
WP_014432147 266 AGVYMIIRTNALWHLSVD-AGQVTAWIGILTALLAASIAIVQTDLKKILAYSTISQLGYMVAAAGLAAYGAALFHLVTHA 344
WP_012616316 277 GGVYLMARTEPLFVASFT-TQGWVAWIGALTALLAGTAAMAQWDIKRVLAYSTVSQLGFMVAACGMGAYVAAIFHLLTHG 355
6HUM_F       351 YFKAMLFLGSGSVIHSMEgvvghnpdlA----------QDMRYMGGLRKYMPITGATFLVGCLAISGVPPFAGFWSKDEI 420
WP_013157738 327 FFKALLFMASGSVIHALGg--------E----------QDIRKMGGMWRYLPQTRWHGLIGALALGGMPLLSGFWSKDAI 388
WP_012683140 351 FFKALLFLGAGSVIHAMHh--------AyhhthrhddpQDLRNMGGLARFMPATAGAMTLATLAIAGVPPLAGFFSKDEI 422
WP_013457332 328 FYKALLFMASGSVIHALGg--------E----------QDVRKMGGLKKYLPRTHLHGLAGALSLAGFPLLAGFWSKDAI 389
WP_015797843 339 FYKALIFLASGSVIHSLDg--------E----------QDVRRMGALRRFMPITAVTMILAWLSIAGVPPFSGFFSKGSV 400
BAN00731     343 FFKALLFLGSGSVIHGMHd--------E----------QDMRKMGKLLKFMPITAGTFIIGWLAIAGVPPFAGFWSKDEI 404
WP_013179429 354 FFKALLFLAAGSVIHALGg--------E----------QDVRKMGGLGKHMRVTGTTALVGTLAISGVPLLSGFFSKDAI 415
NP_295217    357 FFKALLFLCAGAVIHALHe--------E----------QDVRAMGGMRRFMPFTHVAALMGVLAISGIPIWSGFFSKDAI 418
WP_014432147 345 FFKALLFLAAGSVMHATHg--------V----------LDTNRLGGLRAKMPTTYRTFLIGAAALAGIPLLSGFFSKDAI 406
WP_012616316 356 IFKALLFLAAGSVIHGTHd--------T----------QDMRRMGGLKDAMPITFRTYLIGALALAGIVPFAGFWSKDEI 417
6HUM_F       421 LGAVFHA----------------N---PAMWLLTWLTAGLTAFYMFRMYFMTFEGKFRNVPp------------------ 463
WP_013157738 389 LYSTLFYsv------------nsS---LVFYLLLLATAFLTAMYSMRWFVTVFLGQYRGD-------------------- 433
WP_012683140 423 LAGVFARahdsplanasllgipgStvlYAAYGIGILTALLTAIYMTRMLLLAFYGENRTGEae----------------- 485
WP_013457332 390 ITATLTYpf-------------gG---TGFYLAGLAVAFLTAVYAMRWYVLVFLGEYKGS-------------------- 433
WP_015797843 401 LEAAFAH----------------Q---PVLWAIGVVTAVLTAYYMGRLVYVVFYNEPRYQEvl----------------- 444
BAN00731     405 LLFALAE----------------S---PVLYVLGIITAILTAFYMTRQVIMTFFGEQKWGShaneaeaaeldtadtgdet 465
WP_013179429 416 LLHAFTTelia---------gygS---FLIYLTLLATAVLTAFYMFRWYYLVFAGEERFGAea----------------- 466
NP_295217    419 LAAAWAQ----------------S---PWLYVIGLGVALLTAFYMGRWYFLVWRGEYRGQv------------------- 460
WP_014432147 407 LVVALQK----------------N---FAIYGIGIVTALLTAIYSFRAVFVTFHGQPRDQhl------------------ 449
WP_012616316 418 LAHAVSHg---------------H---TPIFLILFLTSLLTAFYMGRQIALVFFGTQRDPs------------------- 460
6HUM_F       464 -------------ERqehhdhhshhaavPHESPWTMTLPLVVLAIPSTLIGFVgtpFNn----------lFEVFIHapge 520
WP_013157738 434 -------------AH-------------PHESPGVMLFPNHILALGAVFIGYIg--LPepf------pnfLERFLE---- 475
WP_012683140 486 ------------rSA-------------LHEAPLIMTAPVLILGVLTLAGGWLn--LPalipi--gpvgvLEHWLS---- 532
WP_013457332 434 -------------GH-------------PHEAPPVMTVPNDVLALGAVFAGFLa--LPepl------wnlVEPYLA---- 475
WP_015797843 445 -----------geRS-------------PHESPRVMTVPLVVLAVAAVLGGLIn--LPfgs------ldfLDRFLA---- 488
BAN00731     466 deatepapvethgAHge---------fkPHESPPFMLLPLVVLAGLAIVGGIIq--LPslgiipknaqhkLLDWLH---- 530
WP_013179429 467 ------------rAH-------------LHESPPLMTTPLIVLAVLSAVAGFIg--LPefaf-----pnlIAPWLE---- 510
NP_295217    461 -------------AH-------------PHEADGLMRFPLGVLAALATLGGFLn--IPaflpslglpkhaFDTYLGr--- 509
WP_014432147 450 ------------yDH-------------VHESGSIMTVPLWILAGLSLVGGVIn--LPfv--------ltLEHWLE---- 490
WP_012616316 461 -------------YH-------------PHESPSVMTVPLIVLAVGAVIGGAIn--LPvl--------hwLTDWLE---- 500
6HUM_F       521 eKVAEHavdl----------------tefLILGGSSVGIGLMGITVAYLMYLK--Gt--pSpqa----iaKAIQPLYQFS 576
WP_013157738 476 -PNLAHleyekp------------slaleWTLVLISALVALAGLYLGYRFFQQ--Kv---Lp--------GWYTRFAQAS 529
WP_012683140 533 -PVTAAsatrlaga-------ghlshdieIVLVGIATGVALLGIVIAVVLYRKpma------------dkAHAPVDNSLL 592
WP_013457332 476 -PALAHvekhhm------------tlgleWGLIALSAVVALVGLYLGYLAFRRw-----tLp--------AWYLTFQTWS 529
WP_015797843 489 -PVFGPslvavh-----------lsgvarAALLATDAVAGLLGVGLAWQLWGH--Rw--rRp--------E-LEPm--VL 541
BAN00731     531 -PLVEFgegaeergigeaiitdtwaydnkVLLIAIAVACALGGIFLGWLVYQK--RrlkaIep--------------dLL 593
WP_013179429 511 -TAAAVsfrhp-------------pvaveWLLIGLSVTAAFLGLGLGYLRYRGgmRe--aRpg-----------aLQRAS 563
NP_295217    510 --AIPQqlhhi-------------panaeWLLTVLAVVAGVVGLGWAWLDHRH--R----Ml---------aNGPLGRVS 559
WP_014432147 491 -PVIGEhekip--------------lvleLLGITVSIVVAVLGVLTARALYLT--Qe--gWakq----laQGFAVLRRPA 547
WP_012616316 501 -PVLHeqag-----------------efnLWLALVATIGAVGMGYLGWWVYTV--Naa-kIkiggkdpayRYSGDIWEGM 559
6HUM_F       577 LHKWYFDELYEAVFIKGCRRLARqv--lEVDYNVVDg-vVNLTGFVTMVTGEGLKYLQNGRAQFYALIVLLAVLGFVIF 652
WP_013157738 530 EHSFYVDQVYNTFIVNPLKSLGNll--fdGDKGLLGg--FSRLGTLTAGLGSLLARLETGYIRFYAAGLVVGAVLLLLW 604
WP_012683140 593 ARAYGVDDIVDTVIVKPVSAVADtvlarGVDRG-IDqgfSLGGSLLSRTASLMGSKLQDGDVGKYAWLLAVGALALIAA 670
WP_013457332 530 TQAFYVDRVYNVLIVNPLKELALvl--alFDG-FLDt-vYLAAAGVGSWLGGLLSRVQTGYVRAYGALMVLGLVAVLVW 604
WP_015797843 542 QRGWYVDATYDRVIARPMTELALea-deVVDPKVIDg-aVMSVAWAARRIGGLGRRVQTGLVRSYLLLMVAGIVVVMGY 618
BAN00731     594 ARGWGYDDAIAWFMGKPGRAgFQav--adGDGKLVDg-aVNGVATLVRETAGQARKAQTGYVRQYAGVIGIGVVLLLGW 669
WP_013179429 564 QEALGFDALYRRLFVRPGEALAQgf--gvVDGELIDk-gLGETALGVGILARASSLLQSGFVRAYALLMLLGLAALVFF 639
NP_295217    560 AAALYLDNIYNGLIAAPSRGIARgl--dvVDRG-VDa-gLSGVARNAGAPGALFARMQSGYVRAYALSMVLGTALIIGY 634
WP_014432147 548 ENKWYVDELYDVLIVRPLRGIADwf-asFFDPKVIDg-aVNGVGGVLNDAGEAVRKLQNGAIPAYALSILAGVVAVLFY 624
WP_012616316 560 EEAWYLDRFYQRTVVAGFERLADfl-arVFDPQGVDg-lVMGIGRFFGSLANGVRALQTGYVRTYALVFTVGVLLVLGF 636
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