Conserved Protein Domain Family
YwcE

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pfam17368: YwcE 
Spore morphogenesis and germination YwcE
The ywcE gene codes for a holin-like protein that localizes to the cell and spore membranes. It is expressed at the onset of sporulation and transcription is repressed during growth by the transition-state regulator AbrB. YwcE is an 83-residue protein with three trans-membrane regions and a highly charged C-terminal tail. Moreover, YwcE has a dual start motif, which plays a role in the regulation of class I or class II holins. It is likely to have the N terminus on the outside of the membrane and the C terminus in the cytoplasm. This family is found in YwcE proteins in Bacilli.
Statistics
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PSSM-Id: 407457
Aligned: 5 rows
Threshold Bit Score: 94.0484
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9KB63               1 MDLFFAYMLVASATPLFLWLEHRKIALTSIPFIIIMWVLALSHMFEGfLFDLHHSVFLTAFFVNVIIAHFAALVLYAYPH 80  Alkalihal...
P39603               2 MDMFFAYLLVASATPLFIWLDNKKVALSAIPPIILMWVFFFFYATES-LSPLGHTLMIILFAVNVIVAHIAAFIIYGLPY 80  Bacillus ...
WP_003215279         1 MDMFFAYLCIATATPLFLWLENRKIALASIPPIMIMWIFFGLYMTSS-LSPAGHTFMIAFFAINVILAHIAAFLIYGLPF 79  Bacillus
WP_007200252         1 MDVYVVYLFVATATPLFLWQDHRKLAMIQIPFIAILWGFVGFYLAGA-LNAEMHLLFNILFVTNVVFAHVAAFKIYAIPF 79  Fictibaci...
GENOMsia:BleG1_2122  1 MDMFFAYMFVASATPLFLWLEHRKIAISSIPFILIMWLLAIAFLFEGfLFHITESTFVIAVLINVVIAHVAALILYTSPL 80 
Q9KB63              81 IRPKSR 86  Alkalihalobacillus halodurans C-125
P39603              81 LRRKRS 86  Bacillus subtilis subsp. subtilis str. 168
WP_003215279        80 IRKRFS 85  Bacillus
WP_007200252        80 IRRERE 85  Fictibacillus macauensis
GENOMsia:BleG1_2122 81 VINKAK 86 
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