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Spore morphogenesis and germination YwcE The ywcE gene codes for a holin-like protein that localizes to the cell and spore membranes. It is expressed at the onset of sporulation and transcription is repressed during growth by the transition-state regulator AbrB. YwcE is an 83-residue protein with three trans-membrane regions and a highly charged C-terminal tail. Moreover, YwcE has a dual start motif, which plays a role in the regulation of class I or class II holins. It is likely to have the N terminus on the outside of the membrane and the C terminus in the cytoplasm. This family is found in YwcE proteins in Bacilli.
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