Conserved Protein Domain Family
PIN_12

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pfam16289: PIN_12 
PIN domain
This domain is found on the N-terminal region of uncharacterized proteins. It shows homology to other PIN-like families and contains several acidic residues critical for chelating metal ions that are conserved in other PIN-like domains.
Statistics
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PSSM-Id: 435258
Aligned: 53 rows
Threshold Bit Score: 72.0379
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Npun_F0413   5 IFIDTNIFL------D-----------FYRVrg----gEQKLNL-LKRVDDH---HDRIITTAQVEMEYKKNR-QIVILE 58 
BAJ32530         2 IILDTSALT------K-------------QGpn----sPLWEVF--AALRSG---GVQLAIPEVVLYELLAQR-ERDYR- 51 
jgi:Metho_1994  19 LFMDTNLFYsetvtyD-----------IFELklmtdllAIRDNFnKIFEGYR---TIKILIPKLVLDEIYSIK-TNIIRY 83 
WP_009106638     6 LIFDTNFII-----------------------------EHSKDL-TDVVEKLs-kTYEVFVTQLSIDERISQQ-YLDLKA 53  Treponema sp....
CCZ52136        11 LIFDTNALF------QayekkadfttfSFNStf----eNVIDMI-NQLDIYN---QVTVAIPSVVWSEMEKQIiEKHNEL 76 
KHD05942         3 IYVESNFVL------Ef----------ALRQaq----fQSCENI-ITLCESG---RACLVLPAFCLAEPFDTL-VRRTKD 57 
Q8YXB4           4 LYIETNFFI------------------GFAKsq----dEDSEKL-VTNISPDrntLTKIVTPSMCCMESLSVL-NHEISK 59  Nostoc sp. PC...
WP_015078020     3 IYLETNSIM------------------AIAKgr----nKELEDF--VYHSSG---NLKFVIPSICLMETLVAI-EREEKR 54  Nostocales
EZH73648         3 IILDTNIFR------Sd----------LFFNsk------dFDIL-RDYLHKT---DSRFVLPQIIIEELTGLY-KRTLDE 55 
WP_014553541     3 IFIDTTLLY------Td---------pFLKNny-------nRNL-LQLVDGL---NGKIFISKVVLEESKENL-KKNLEK 55  Halanaerobium...
jgi:Npun_F0413  59 Slnkf--ktpdWGGLTPPAFLSDAQPA----IAITKSKSEIss----qQNKLKKRIEAi---LKNPSTN-DPVFKILQRL 124
BAJ32530        52 ------------SALDAARSAYDTLWAlqftDEDGVAYWPAvpnveqhVDEWEQRYRGs--lTVLPLTL-DAAREGLRRE 116
jgi:Metho_1994  84 E----------FNNFIKKIKKINEKTLiaslNHIYNNIYSNle---ssGNSFISRNKIe---IIPYCDN-TYFPTIIEKS 146
WP_009106638    54 K----------YDKARTLATEIQSFAKlefiKEFDDAFGTTka---gvQNNYIHLFPNki-iPFSKSEE-TY-AEIIDRV 117 Treponema sp....
CCZ52136        77 Lsty----kstISKKRFPEYSIQENPDidypEYIKNKIAEYkkeisvgMNKVIE----------IPIASsNRFESIINRA 142
KHD05942        58 RkelkkkldieFNQLSRTALYTNQLDSl--rEVSQILIQSSleeeqrlHQALLKILKVc---EVIQIVP-SI-LTLAADY 130
Q8YXB4          60 SnrfqdnldleRKKLKGDKNSQYSREIqrclQEVKIKNEARln---eiNNRLVQVLEWa---TMNVELI-QLKPDILSTS 132 Nostoc sp. PC...
WP_015078020    55 SqsfsqtiqieMNEGKRNKGLTNSQSFanylELCLIDYGKVlr---dfRKRFLNILEYl---KNHCELI-EPSIKMLEAT 127 Nostocales
EZH73648        56 N----------QRNYNKARKNLNQGLNyelvDELNINCDEEvk---kyIDFVYNKLGRke-eKNIPYKN-EYLPEIVKRA 120
WP_014553541    56 A----------QNNLLKDIREFNKYSNskidIKNDLKSIDQhv---kdFENYYKNLESrdlvKIVDYKN-SYLPEVVKRA 121 Halanaerobium...
jgi:Npun_F0413 125 FRSKSDFnlsrekkirfkirglawkrfilgyppRKd------KDTSIGDAINWEWIIHCAE----NT--EKd---IILVT 189
BAJ32530       117 AYRLRPArs-----------------------sGK-------TAIGSRDAAIWMTVVEQARr---GG--EP----VHFVS 157
jgi:Metho_1994 147 ITKSLPFkp-----------------------yFDqrknrdvGDNGFKDTVIWYSIMDYVKk---KC--TEntnhIFFLT 198
WP_009106638   118 YKKTAPFi------------------------aRS-------SDKGFKDTILWLSLIEYFSk---NTnfES----VTFVS 159 Treponema sp....
CCZ52136       143 FGKLPPFeg----------------------kdKK-------SDKGFKDALLWESILEFSLt---HC--NLk---IIYYS 185
KHD05942       131 --RLAPF------------------------------------ELDIQDAIVYASIVHHLSi---SKlaSR----KCFIN 165
Q8YXB4         133 LQEQLIA--------------------------------------DQTDNLILHCILDHARihqnTSpdDK----KILLT 170 Nostoc sp. PC...
WP_015078020   128 LTNPLLP-----------------------------------GKNQKRDDFILQVILAHAEn---NLs-IN----KAFFS 164 Nostocales
EZH73648       121 INKQKPF--------------------------KD-------EDKGFRDSIIWLTILDYCQg---CH--EKq---ITFIS 159
WP_014553541   122 IQRKKPFa-------------------------PG-------NKQEFRDCLIWLSYSEIAEr---DN--LDn---CFFIT 161 Halanaerobium...
jgi:Npun_F0413 190 RD-TDY 194
BAJ32530       158 LNsNDF 163
jgi:Metho_1994 199 DNeKDF 204
WP_009106638   160 ND-HGF 164 Treponema sp. JC4
CCZ52136       186 KD-NAF 190
KHD05942       166 RNsRDF 171
Q8YXB4         171 ANsRDF 176 Nostoc sp. PCC 7120
WP_015078020   165 ENtKEF 170 Nostocales
EZH73648       160 NNpKDF 165
WP_014553541   162 NNvSDF 167 Halanaerobium praevalens
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