Conserved Protein Domain Family
LcnDR2

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COG4403: LcnDR2 
Lantibiotic modifying enzyme [Defense mechanisms]
Statistics
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PSSM-Id: 443528
Aligned: 127 rows
Threshold Bit Score: 110.984
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_083765720  107 SLYSGMPGVVLFYLELHHATGDARYLREAQSGARALVAA-LPpe-----gvGAAGAGLYTGLTGIAYVLQLVQERAPfaa 180 
WP_012789112   29 GLLGGYTGAALFYAYYYQLTEKEEHLNKIHQLLERALHD-LAa--------TALPFSHCNGIAGMVWCIQHLIKAGFag- 98  
WP_012300330   42 NLGDGHAGVSMALFEATLSTGId-fDREAMAHLRSAVQLsn--------taPFTSLGLFDGAAGLAAAMAers------i 106 
WP_013398294  609 DLYSGSIGPALSLAQAAHTLENEEYAQAAYRVFDPIADVvFSedms-felpDEMRDTAFMGEPGIAFALAGAAECLN--- 684 
WP_013398309  638 ELFSGSVGVALNLVRSGVIFEEPAWVSAGESFFQKTLAN-LAngt----dwENIHHGAQSGVESFLWAAMEVFELLG--- 709 
WP_041321664  665 DFYTGSTGAALALTQAARTLGKPEYTQTARRVLDPIAQDvFAdrlf--sipPETCDGISCGETGIAFVLAAAAENLR--- 739 
WP_114901586   28 GVLAGLGGISLFEFYYSKYLDIDDHADIGVEMLTNCIDK-INe--------GYSYPTFCTGIAGAGWVLDHLEQEEFmd- 97  
WP_114904390   34 GVLAGLSGISLFHFYYSRYLNNSEQVEKGSEVLMTCVEK-LNn--------GFSQLAYCNGISGFGWVLDHLKQHDFig- 103 
WP_116111948  223 DLYTGRLGVGLGMARGVRALGSPLFELVACQLFDNTASI-LSdetydpeniGSMGRGAYTGVAGVAWALWTAGRTLE--- 298 
WP_118501120   29 GVLSGISGVALFQFYYSKYIEDDSHADKGAETITRAIDL-INe--------GVIYPTFCTGIAGACWVLEVLKEEEFve- 98  
WP_083765720  181 gQ--TALAQIAERVRGsAswk--------geAAVWQ-DSTDIISGTAGLALALVWLQARDRa-SASp--WRDssrVLRGA 246 
WP_012789112   99 eDelEDIFEEVDEVLGkEmls-----------alQQ-REYDFLHQGLGIALYFLERNHYTA---------AEk--WLPAL 155 
WP_012300330  107 vD--ERLLPSARRFHQvVvtqlgagtpppgsGFADG-SPHDVISGTAGQLLYLSAIPRAVCgpDDRa--------VASGL 175 
WP_013398294  685 -D--PRLKEAAAVLGN-Ria---------erLAQAEhPSPDYLTGQVGAAALLLGYDLADD--REA---LLG---VLDRH 743 
WP_013398309  710 -D--KQGHQKAVRVLAqClsk-------------stlYDLDVSSGYAGIVLAFSPHIDSDS--TGT---LAD---LVAFS 765 
WP_041321664  740 -D--TRFAEAAVKVGD-Rta---------arLAQVEhPMPGYLDHQVGAAALLLGYNLATD--RAA---LLA---VLDRH 798 
WP_114901586   98 aDn-DDLLPELDQYIYtFmvt-----------dmKN-GNYDFLHGAIGYAFYFLNRYRNTK--SDElkeKYRg--FINEF 160 
WP_114904390  104 iDa-DGLLTQFDANLEiFmmk-----------stEN-ENYEFLYGALGTAYYFLNRYENTE--TAAakeQYKi--ILLKF 166 
WP_116111948  299 -R--SDWCDVATTSLAaIvea--------asPERDS-KFLDVIAGVPGLFTVARTIGAPID---------LEp--LRHRV 355 
WP_118501120   99 lDe-DFLSSDLDAYLLqAmka-----------diET-ENYDFLHGAMGYGYYFLKRYQNVT--NSEskkAYKe--YLDLL 161 
WP_083765720  247 ARS---LLDAGVSEgNG-----------TKWAIs--------sSTPR-RYPNFSHGTAGVSYTLATLAMHpaLA-DDRTL 302 
WP_012789112  156 VDN---LQSTAIETpAG-----------ITWKDqltglsdqpaGSRS-FNLGLAHGVPAIIAVLGMIHRKg-IA-VAQTE 218 
WP_012300330  176 MDVladLLQAGTSVtEAftvdrryfmpgSTYEAl--------sTGDf-VDLGTAHGVAGIALALASAAKR--FGaQPVVI 244 
WP_013398294  744 AQD---IIAGrv---------------eEEWw----------------SHSGFAHGISASIFALSRWNRQ--MP-SSERA 786 
WP_013398309  766 VNS---LVQGAQALdVA-----------------------------SlQYSGFAHGVCGLYAALARTKGLe---iENEAT 810 
WP_041321664  799 AQD---IIAGmv---------------eENWw----------------HRSGFAYGISGSIFALARWNRQ--MP-SPERA 841 
WP_114901586  161 IDL---LEGLSEDAgDGk----------LRWESels----ietKERG-YNLSLSHGMSSIVGILTKFHEQd-DF-KEKSE 220 
WP_114904390  167 LSL---LSKTAIQIdDDk----------IVWNSiln----pntNANG-YNLGVAHGISGIIGILSKMHQHn-DF-RTKTQ 226 
WP_116111948  356 MAA---VVDGl-----------------ENYEV-------------N-TQSGFAHGLSGLLFHLATTGPVp--------- 392 
WP_118501120  162 INA---LKNSSLNKdDN-----------VWWETeli----kdeGTMG-CNLSLSHGMSSNINFLSRIAEHs-EF-YDDVK 220 
WP_083765720  303 QrAARegalSGARYLDGITt-tSPSGarki------fhsEPGNESLYYLSWCHGPAGTGRLYRQLERLTGDA-TW--RR- 371 
WP_012789112  219 T-MIR----KGLSWLEACQnqpGEENtslypvl-vdqhhqaLTGKQSRLGWCYGDLGIATTLLNAGNWLQDD-YY--TE- 288 
WP_012300330  245 D-QLR----RMRDWLLDTAv-pDPSGclqwprglevhgsvtMPSTGSVCAWCFGSSGPAVALLRIAELLDDE-SS--AS- 314 
WP_013398294  787 QhAVN----ILLERLREFDngesw-------------esqiSGQGSRNGVWCHGTAGISLALAAVQVWMP---GLstRA- 845 
WP_013398309  811 DsLIK----KLLTFETKFKtadg-------------gyrFGDEGTPEAKGWCHGLPGHHLAHAILHHYATDLsPF--TDa 871 
WP_041321664  842 ReAVE----ILLRRLNDFNtgdewra---------qltehdSGEEHASGTWCSGSAGIALAFAALHLWMP---ELasRT- 904 
WP_114901586  221 P-LLK----GAVKYILNFKt-tKEDPfsifpsw--vtgkeeDENAQSRLAWCYGDLGVAMRFWYASKTLNDE-AL--GK- 288 
WP_114904390  227 P-LLK----QTVNYILSCKn-eEEVVfsyfpn---sikqeeKGTGKSRLAWCYGDLGIGTLLLKASEALQDA-TL--KN- 293 
WP_116111948  393 D-VITe---TLMQRLGSFW---RPAElnw---------stnDTHNRATHGWCHGRAGVTMGVAASg---vDPgTYg-LP- 451 
WP_118501120  221 E-LLK----NASHYILSCKn-kDTTLtatfpn---wvveenADESGSRLAWCYGDLGIGLSLLRVGKQLNDT-KL--YN- 287 
WP_083765720  372 YQPALAKAIVESGvpeqhpdrsgFWNNISQCCGNCGVAEYFVARHAAT-RSADD---LAFAQR-----VMDDVIRRaTPD 442 
WP_012789112  289 SALRIFHHTIRNRnih-----nsFVHDACLCHGSAGIAHIYRRAWLQT-NESFL---LNGATD-----WLQHTLQMnTHK 354 
WP_012300330  315 AMQASIESNVEafi-------stPTTDSSLCHGAAGMLVLHSLTSggT-TVPST---RWAANDa---lLVSRILQS-IDA 379 
WP_013398294  846 DLERAVHHALHEG----------TGRNLTYCHGDLGTLDILEWVVNHV-PDLp---dAEKIRDiltngYSTSLLQEtLED 911 
WP_013398309  872 DLQVESERIRNTC----------FGGNISLCHGDIGNFWVLLDASRLL-NYPEI---GALTKK-----AAADYVERilpv 932 
WP_041321664  905 DLDRAVQHAFRTG----------TRSNLTLCHGDFGTLDALAWIADRI-PDVp---cAEAIRDaiengYSASDIRAvLDD 970 
WP_114901586  289 TALEVLKHAAKRTave-----dsLVRDAGICHGSYGNAQMFLRMYKET-GDQDF---KDAFEF-----WIQDGINRgTFE 354 
WP_114904390  294 EVLDILRHAAKRKtea-----etWVNDAACCHGAFGNALLFKRIYQHT-EETIF---KETADF-----WFETGFNMiHYG 359 
WP_116111948  452 DLTTLVTAIGEDA----------TGYNITHCHGDLGNYDMLRWLV--ThKTPDLghvLEKVQHt----LQAGSLSRkl-- 513 
WP_118501120  288 GALSALKYSTKRRdid-----eaGVMDAGLCHGAYGIMHIYHYLYKTT-NEVVF---KETADF-----WAEKSLELaIHT 353 
WP_083765720  443 AGGLKwvqa-enrTSP-DDViAQTGFMQGAAGVGIALLHMEGALrerRpl-vvLPD 495 
WP_012789112  355 EGPAGfr----flGKD-DYE-NSYGILEGVAGIGLSLIAAIDPDt--------DPA 396 
WP_012300330  380 DAPFGiv----saGLDgRPL-HDPTFLMGAAGTLATIAGRTRDA---------HPI 421 
WP_013398294  912 KSVRY------------S---LTPSYMVGTSGVLSWLSRRIGGT---RlytpiIPD 949 
WP_013398309  933 ----------alkDVN-RHT-ITQSLMVGTGSPLAFLGKLQRHE---------LRS 967 
WP_041321664  971 KSVRY------------S---LTPSFMVGTSGVLSWLTRRADNA---RpysplIPE 1008
WP_114901586  355 DGYAGykq--wkgVDK-SWA-AEVSLLEGIAGIGLSILDYLADY---------DTN 397 
WP_114904390  360 KDDARvre--wkmNAD-HWK-STSSLIEGAAGIGLVIIDFLAED---------DLH 402 
WP_116111948  514 -----------ddPHS-RYS-LNDGLMVGRAGVLLYAAERIDQSls------iSPT 550 
WP_118501120  354 EGYAGymmwrggqKDN-NWK-PSVDLLEGIAGIGLSMISYLASF---------DTK 398 
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