4IRP


Conserved Protein Domain Family
Glyco_transf_7C

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pfam02709: Glyco_transf_7C 
N-terminal domain of galactosyltransferase
This is the N-terminal domain of a family of galactosyltransferases from a wide range of Metazoa with three related galactosyltransferases activities, all three of which are possessed by one sequence in some cases. EC:2.4.1.90, N-acetyllactosamine synthase; EC:2.4.1.38, Beta-N-acetylglucosaminyl-glycopeptide beta-1,4- galactosyltransferase; and EC:2.4.1.22 Lactose synthase. Note that N-acetyllactosamine synthase is a component of Lactose synthase along with alpha-lactalbumin, in the absence of alpha-lactalbumin EC:2.4.1.90 is the catalyzed reaction.
Statistics
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PSSM-Id: 460659
Aligned: 51 rows
Threshold Bit Score: 65.3255
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4IRP_A       105 GPFHVASPELHPLYHYKTYVG-GILLLSKQHYRLCNGMS-NRFW--GWGREDDEFYRRIKGA-GLQLFRPSG-ITTGYKT 178
XP_002053982 260 PRVLAVEELPEWPYSSPTFAG-GILMISREWFHQLHGFN-PHLE--IWGGESIELAIKLWLC-GGQIEIVPCsRIGHIFR 334
XP_001638687 119 TRLHCGFTP-SIPYGFWELQGyGLFAIYKSDFIRVGGMN-YREFgtQWGGEDWELLDRVLLS-RMEVERL---RIPNFYH 192
XP_001641406 126 LRLRCG-NYPKVPFGYWENLGfGLLALFKSDFDRVGGMNvDGFK--GWGGEDWELLDRVLES-QMEVERL---KIPEFYH 198
Q8R632       164 EKFYNFLYKLKLRSRGAKIVG-LIFSLFKEDFININGLD-EKYI--GYGYEDDDFGNRFFKY-GGETFAFKM--KRYPIH 236 Fusobacterium n...
Q7VI35       413 NASKITSSFFDKKDFIKGIRG-CNMSFFKTDCISINGFN-EAFI--GWGREDSEFVARFLFN-GGEMRRLKF--AGIAYH 485 Helicobacter he...
WP_013186339 156 RIPFLANSYKKEDSRSSKLRG-CNMSFWRDDFIKVNGFN-EGLT--GWGIDDSEMIQRLINI-GVKGKRLKF--KGIVYH 228 Croceibacter at...
Q5LIR3       155 STPVSNFFADRYKKNVSSGLG-CNMSFWRSDFLAINGYD-EFFE--GWGKEDDDLTHRLQRK-GCK-KRSLR-FAGIVYH 227 Bacteroides fra...
CAL92645     107 GHFYRAAADAKGKRDGETF---GTVICERAAFERIGGYD-EAFR--GWGGEDTDLYARLAAQpGLREAGYPA---HFVEP 177
WP_013187216 127 TQRDKEFEHCNIKFESTSEAT-GLTMFPVENLKKIHGFD-EFYH--FWGSEDTDVHVRLKHS-GCDVQFYDK----DILM 197 Croceibacter at...
4IRP_A       179 FR--HL 182
XP_002053982 335 VRhafe 340
XP_001638687 193 FY--HS 196
XP_001641406 199 FY--HT 202
Q8R632       237 MY--HK 240 Fusobacterium nucleatum subsp. nucleatum
Q7VI35       486 LY--HP 489 Helicobacter hepaticus
WP_013186339 229 IY--HK 232 Croceibacter atlanticus
Q5LIR3       228 LW--HG 231 Bacteroides fragilis NCTC 9343
CAL92645     178 IP--HD 181
WP_013187216 198 LHqwHE 203 Croceibacter atlanticus
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