4HET,3S30


Conserved Protein Domain Family
PCMD

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pfam13201: PCMD 
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Putative carbohydrate metabolism domain
This domain has been suggested to participate in carbohydrate metabolism. Structural evidence indicates that it might be a carbohydrate binding domain, with or without enzymatic activity. In particular, it has been hypothesized that it might act as a glycoside hydrolase.
Statistics
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PSSM-Id: 433034
Aligned: 80 rows
Threshold Bit Score: 105.511
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4HET_A       114 NFEEllpsndydifyefqpgtsqeiskvlqWSSGNP----GFKLTG------XA-----------NSktdyptvQ-VANG 171 Bacteroides the...
CDE06588     291 sFDQwwlknkkiwc-------pwpengiqfWDTGNT----GAATlgnsn------------vtpsDD-------TpTGTg 340
CCY34968     301 gFDAwnttggvvyp-------nadqnenfwWDSGNT----GARLggktptsqeT-----------SF-------LaTSDE 351
CCZ44264     353 sFDSwymngkapm--------pdiqgepliWDTANP----GSASlgtvptnpeS-----------S--------HvAVPG 401
CDA93756     131 NFDDwsmagkgwypf----gksvpdadkkiWATANK----GTAS-L------Grntt-----epeET-------FvAVPG 183
CDC63616     130 SFDNwamvgkgwypy----aadasdneksiWTTANK----GTADLL------Nrntt-----tpeES-------FvAVPG 183
CCZ43411     129 SFDNwalegkgyfpy----apdasdsdkaiWTTANK----GTSDLL------Gkntt-----ipeEE-------FlAVKG 182
CDD32840     355 NFDLwsesgstiypg----saeeagnttsfWNTSNP----GTTQGI------GaiggavnpttgvQS-------PvHTTG 413
CDE66007     295 gFEEwetidkvvy--------pyladgihfWNSGNK----GASIgnat--ptdK-----------TT-------DvRPGT 342
WP_021987798 225 DFELwinegsksvn------idptpgeglgWATANNsfvqGTKPVL------Y--------------------------- 265 Culturomica mas...
4HET_A       172 fRG-KGVKLETrdtgsfgaxV--K-XY-------IAAGNLFIGTFEVGNAltdp-rkaTNFGFQFYKRPKTLKGHYKFKA 239 Bacteroides the...
CDE06588     341 ----QSACLAT---------RfvG-Igsi---gkLAAGSIYTGTFVrvdg----tngiLDFGRPWSvRPTRVRGFYKFHT 399
CCY34968     352 -GNtSAARLET---------VnaL-Ia-------MAGGNVFSGYFGsiqg----lgaeVFFGRPFEsRPLTLSGYYSYEP 409
CCZ44264     402 -EGkKAAKLESl--------AatMdI--------FAAGNIFTGKFGkaiaslsnpgatLDWGTPFYsRPLALKGYMDYRP 464
CDA93756     184 -PGkKAAKLSS---------QyiV-Mk-------FGSGNIFTGEFCkligm---sgadMAWGVPFTgRPKSLHGYFCYQP 242
CDC63616     184 -PGkYAAKLSS---------QliL-Ik-------FASGNIYTGEFCvlkgt---kgadLAWGIPFTeRPKSLHGYYCYQP 242
CCZ43411     183 -PGkKAAKLTS---------QfiA-Ik-------FASGNIFTGEFCglkgt---kgadLAWGVPFTdRPKSLHGYYCYQP 241
CDD32840     414 -EGaYAAKLQT---------Tnkl--------gvLAAASLYTGSFLglsg----msanMEFGKPFTsRPVALHGYYMYTP 471
CDE66007     343 -SGiYAAQLSS---------KlaG-Lvgv---ykLAAGNLFTGIFYgirnl---thgiVCFGQPFEaRPTALHGWFKYNQ 405
WP_021987798 266 -NGgKAAEMTTg----------lQnLNslgigelITAGTIFTGKFKMKISalnnppamTHFGIPFTLKPISISVDAKYIA 334 Culturomica mas...
4HET_A       240 GDVYSv----E-GKPQE--GV-----------RDKCDIYA-VXYEA-E-N-N--SVXLNGDd------vFT--------- 280 Bacteroides the...
CDE06588     400 EPIn------Y--ASTefkh--------ligrPDSCHIYV-ALADwd--------------------apYQirtnpnnrq 442
CCY34968     410 VTId------NvKPPSG--VElpfdestiagqSDRCHIFV-YVTAwd--------------------gpYRvntteh--r 458
CCZ44264     465 VAIt------HaKSpyte----------lkgrPDTCQIQI-FLTDrt--------------------tmYHidtqkk--q 505
CDA93756     243 KTId------YaDDshka----------mlgkTDIGQIQI-ILAD----WdKnkWSNYPAGaiddqgrfHVinsdsq--f 299
CDC63616     243 VTId------NaDDshkd----------llgkMDIGQVQI-ILAD----WdKnkWSGYPDGaiddkgrfHVvnsdgq--f 299
CCZ43411     242 KAIn------HtDKahes----------mkgqTDIGQIQV-ILAD----WdKhkWDGYPDKaidekgrfHVinsdsq--f 298
CDD32840     472 QVIn---------RVSR--VPegvei-tkdetMDQCAIFI-ALAKk----------------------tFTfnnnkeeey 516
CDE66007     406 GMLt------NvGSTQP--Pgmnl----kvgdPDNGMIYI-AVGT----WtPeeYGISQGEqfgsaenpIAidtrnp-ss 467
WP_021987798 335 GSQLQqsvkeSgKYKLHnlTG-----------TDSGRIWVkILHWGgKgAlEyhEKPVPDL------------------- 384 Culturomica mas...
4HET_A       281 ----S-DKLVSLARIk-pEDVVEs---D-QWTDFEIPFEPvkgrvIDdtklKNGKYK------LGIVLSSSVDGAYFKGA 344 Bacteroides the...
CDE06588     443 lldkNsPAIIAYGEl--iRGSDtn-----gWQEFEVTFNYr---sTS----RKPK-Y------ILVCFAASKYGDYFTGG 501
CCY34968     459 yldiNdPDVLGYGELideVGTGGe------YKQFTINIKYre-snRN----VKPT-Y------CAVVAVASQYADYFTGG 520
CCZ44264     506 fvdiNgSDVIAYGKLesgTVTSTkeglVnGYEPFEIKLEYr---dLT----RKPN-M------IVIVAAASKYGDFFTGG 571
CDA93756     300 vdydNdPAIIGYANFefsNw------mDa-YEEFDIPITYr----sD----RTPT-M------VAIVAASSRHGDFFTGA 357
CDC63616     300 idfdNdPAIIGYGNFefsKw------mDn-YEAFDIPITYr----sD----RTPS-V------VVIVSASSRYGDYFTGG 357
CCZ43411     299 idfeNdPAIIGWGNMefsKw------mDs-YQEFNLPITYr----sD----RTPS-V------VVIISASSRYGDYFTGA 356
CDD32840     517 idyeGdDNIIAYGELpsgAATPgs-----dYTEFTIPLKYke-sqFG----EQPT-H------IIIVCSASKYGDYMTGG 579
CDE66007     468 ffdpTsPAVIGYGQLpltASYSe-------WQEFTIPLKYv---aTD----RKPT-H------IVVVCSASRWGDYFIGS 526
WP_021987798 385 -------TILGEGELifdGKNQT----LkNWHTYTIPIEY------------NSAYNhiepthIAIVMTSSRKGDIFIGA 441 Culturomica mas...
4HET_A       345 VGSTLYVDEVELI 357 Bacteroides thetaiotaomicron VPI-5482
CDE06588     502 TGTTLYVDQVSLD 514
CCY34968     521 IGSLMYVDEFSfg 533
CCZ44264     572 KGTVLYLDEFSFV 584
CDA93756     358 AGTVLYLDEFSfk 370
CDC63616     358 NGTVLYLDEFSFV 370
CCZ43411     357 EGTVLYLDEFEFV 369
CDD32840     580 DNSLLYVDDFSLV 592
CDE66007     527 TSSVLVVDDLELI 539
WP_021987798 442 VGSKLTADNVVIN 454 Culturomica massiliensis
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